Malaria Journal 2008

Host erythrocyte polymorphisms and exposure to Plasmodium falciparum in Papua New Guinea.(Research)

Jan 03, 2008; Fowkes, Freya JI. ... Authors: Freya JI Fowkes (equal contributor) [1,2]; Pascal Michon (equal contributor) [1,7]; Lynn Pilling [1]; Ruth M Ripley [4]; Livingstone Tavul [3]; Heather J Imrie [1]; Caira M Woods [2]; Charles S Mgone [5,9]; Adrian JF Luty [6,8]; Karen P Day (corresponding ...

The costs of introducing artemisinin-based combination therapy: evidence from district-wide implementation in rural Tanzania.(Case study)

Jan 07, 2008; Njau, Joseph D. ... Authors: Joseph D Njau (corresponding author) [1]; Catherine A Goodman [2,3]; S Patrick Kachur [4]; Jo Mulligan [2]; John S Munkondya [1]; Naiman Mchomvu [1]; Salim Abdulla [1]; Peter Bloland [4]; Anne Mills [2] Background For over a decade, malaria ...

Recombinant human erythropoietin increases survival and reduces neuronal apoptosis in a murine model of cerebral malaria.(Research)

Jan 07, 2008; Wiese, Lothar ... Authors: Lothar Wiese (corresponding author) [1,2,3]; Casper Hempel [1,2,4]; Milena Penkowa [3]; Nikolai Kirkby [2]; Jørgen AL Kurtzhals [1,2] Background Plasmodium falciparum malaria remains a massive burden of disease with an ...

Risk factors for house-entry by malaria vectors in a rural town and satellite villages in The Gambia.(Research)

Jan 07, 2008; Kirby, Matthew J. ... Authors: Matthew J Kirby [1]; Clare Green [1]; Paul M Milligan [2]; Charalambos Sismanidis [2]; Momadou Jasseh [3]; David J Conway [3]; Steven W Lindsay (corresponding author) [1] Background To achieve a reduction in malaria morbidity, the design and ...

Improving equity in malaria treatment: Relationship of socio-economic status with health seeking as well as with perceptions of ease of using the services of different providers for the treatment of malaria in Nigeria.(Research)

Jan 08, 2008; o­nwujekwe, Obinna ... Authors: Obinna o­nwujekwe (corresponding author) [1,2]; Benjamin Uzochukwu [2,3]; Soludo Eze [2]; Eric Obikeze [2]; Chijioke Okoli [2]; Ogbonnia Ochonma [1] Background Equitable improvement of treatment-seeking for malaria will depend partly o­n how ...

Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites.(Research)

Jan 08, 2008; Ajayi, Ikeoluwapo O. ... Authors: Ikeoluwapo O Ajayi (corresponding author) [1]; Edmund N Browne [2]; Bertha Garshong [3]; Fred Bateganya [4]; Bidemi Yusuf [1]; Peter Agyei-Baffour [2]; Leticia Doamekpor [3]; Andrew Balyeku [4]; Kaendi Munguti [5]; Simon Cousens [6]; Franco Pagnoni [7] ...

Monitoring the operational impact of insecticide usage for malaria control o­n Anopheles funestus from Mozambique.(Correction)(Correction notice)

Jan 09, 2008; Casimiro, Sonia LR. ... Authors: Sonia LR Casimiro [1]; Janet Hemingway [2]; Brian L Sharp [3]; Michael Coleman (corresponding author) [2,3] Since publication of our article [1], we have been made aware of several errors in our article. In the Background section, paragraph 4, ...

Malaria risk and access to prevention and treatment in the paddies of the Kilombero Valley, Tanzania.(Research)

Jan 09, 2008; Hetzel, Manuel W. ... Authors: Manuel W Hetzel (corresponding author) [1,2]; Sandra Alba [1,2]; Mariette Fankhauser [1]; Iddy Mayumana [2]; Christian Lengeler [1]; Brigit Obrist [1]; Rose Nathan [2]; Ahmed M Makemba [2]; Christopher Mshana [2]; Alexander Schulze [3]; Hassan Mshinda [2] ...

Distribution of Anopheles in Vietnam, with particular attention to malaria vectors of the Anopheles minimus complex.(Research)

Jan 11, 2008; Garros, Claire ... Authors: Claire Garros [1,2]; Cam Van Nguyen [3]; Ho Dinh Trung [4]; Wim Van Bortel [5]; Marc Coosemans [5,6]; Sylvie Manguin (corresponding author) [1] Background The main malaria vector Anopheles minimus s.l. (Myzomyia Series, ...

Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum.(Research)(Immunoglobulin G)

Jan 11, 2008; Guitard, Juliette ... Authors: Juliette Guitard (corresponding author) [1,2]; Gilles Cottrell [1]; Nellie Moulopo Magnouha [1]; Ali Salanti [3]; Tengfei Li [1]; Sokhna Sow [4]; Philippe Deloron [1]; Nicaise Tuikue Ndam (corresponding author) [1] Background ...

How antimalarial drug resistance affects post-treatment prophylaxis.(Review)

Jan 11, 2008; White, Nicholas J. ... Authors: Nicholas J White (corresponding author) [1,2] Background In areas of intense malaria transmission reinfection following antimalarial treatment is inevitable. Antimalarial drug treatments with slowly eliminated drugs provide a variable period, ...

Estimation of heterogeneity in malaria transmission by stochastic modelling of apparent deviations from mass action kinetics.(Research)

Jan 11, 2008; Smith, Thomas A. ... Authors: Thomas A Smith (corresponding author) [1] Background Heterogeneity in transmission rates of parasitic infections is a major source of uncertainty in predictions of the impact of control measures. In general, heterogeneity decreases the ...

Polymorphisms of TNF -enhancer and gene for Fc[gamma]RIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population.(Research)

Jan 14, 2008; Sinha, Swapnil ... Authors: Swapnil Sinha [1]; Shrawan K Mishra [1]; Shweta Sharma [1]; Phani K Patibandla [2]; Prashant K Mallick [3]; Surya K Sharma [4]; Sanjib Mohanty [5]; Sudhanshu S Pati [6]; Saroj K Mishra [5]; Bheshaj K Ramteke [7]; RM Bhatt [8]; Hema Joshi [3]; Aditya P Dash [3]; ...

Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts.(Methodology)

Jan 14, 2008; Golnitz, Uta ... Authors: Uta Gölnitz (equal contributor) [1]; Letusa Albrecht (equal contributor) [1]; Gerhard Wunderlich (corresponding author) [1] Background Plasmodium falciparum the causative agent of tropical malaria still kills over o­ne ...

Comparison of all-cause and malaria-specific mortality from two West African countries with different malaria transmission patterns.(Review)

Jan 18, 2008; Ndugwa, Robert P. ... Authors: Robert P Ndugwa [1]; Heribert Ramroth [1]; Olaf Müller [1]; Momodou Jasseh [2]; Ali Sié [3]; Bocar Kouyaté [4]; Brian Greenwood [5]; Heiko Becher (corresponding author) [1] Background Mortality rates in sub-Saharan Africa (SSA) remain very ...

Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria.(Research)

Jan 19, 2008; Ndiaye, Jean Louis A ... Authors: Jean Louis A Ndiaye (corresponding author) [1]; Babacar Faye [1]; Amadou M Diouf [1]; Thomas Kuété [2]; Moustapha Cisse [3]; Papa A Seck [3]; Phillipe Brasseur [4]; Albert Same-Ekobo [2]; Valerie Lameyre [5]; Oumar Gaye [2] Background Nearly ...

The effects of a partitioned var gene repertoire of Plasmodium falciparum o­n antigenic diversity and the acquisition of clinical immunity.(Research)

Jan 23, 2008; Recker, Mario ... Authors: Mario Recker (corresponding author) [1]; Nimalan Arinaminpathy [1]; Caroline O Buckee [1,2] Background Although the acquisition of immunity to malaria is poorly understood, it appears to rely o­n repeated exposure to different antigenic variants ...

Multiplicity of Plasmodium falciparum infection in asymptomatic children in Senegal: relation to transmission, age and erythrocyte variants.(Research)

Jan 23, 2008; Vafa, Manijeh ... Authors: Manijeh Vafa (corresponding author) [1]; Marita Troye-Blomberg [1]; Judith Anchang [1,2]; André Garcia [3,4]; Florence Migot-Nabias [3,4] Background Multiplicity of infection (MOI) is the number of different Plasmodium falciparum ...

Characterization of two putative potassium channels in Plasmodium falciparum.(Research)

Jan 24, 2008; Waller, Karena L. ... Authors: Karena L Waller [1,5]; Sean M McBride [2]; Kami Kim (corresponding author) [3,4]; Thomas V McDonald (corresponding author) [1,2] Background In the course of a persistent human infection, Plasmodium falciparum parasites are ...

A tool box for operational mosquito larval control: preliminary results and early lessons from the Urban Malaria Control Programme in Dar es Salaam, Tanzania.(Methodology)

Jan 25, 2008; Fillinger, Ulrike ... Authors: Ulrike Fillinger (corresponding author) [1]; Khadija Kannady [2]; George William [2]; Michael J Vanek [3]; Stefan Dongus [3,4]; Dickson Nyika [5,6]; Yvonne Geissbühler [2,3,5]; Prosper P Chaki [1,2,5]; Nico J Govella [1,2,5]; Evan M Mathenge [7]; Burton H Singer ...

In vitro atovaquone/proguanil susceptibility and characterization of the cytochrome b gene of Plasmodium falciparum from different endemic regions of Thailand.(Research)

Jan 28, 2008; Khositnithikul, Rommanee ... Authors: Rommanee Khositnithikul [1]; Peerapan Tan-ariya [1]; Mathirut Mungthin (corresponding author) [2] Background Multidrug-resistant falciparum malaria is a major health problem along Thai-Myanmar and Thai-Cambodia borders. WHO has recommended ...

Pilot assessment of the sensitivity of the malaria thin film.(Research)

Jan 28, 2008; Ohrt, Colin ... Authors: Colin Ohrt (corresponding author) [1]; Wendy Prudhomme O'Meara [2]; Shon Remich [3]; Peter McEvoy [4]; Bernhards Ogutu [3]; Ramadan Mtalib [3]; James Sande Odera [3] Background Light microscopy is the reference or "gold" standard for malaria ...

An interactive model for the assessment of the economic costs and benefits of different rapid diagnostic tests for malaria.(Research)

Jan 28, 2008; Lubell, Yoel ... Authors: Yoel Lubell (corresponding author) [1]; Heidi Hopkins [2]; Christopher JM Whitty [3]; Sarah G Staedke [3]; Anne Mills [1] Background The role of RDTs and decisions in their implementation In sub-Saharan Africa, management of febrile ...

From chloroquine to artemether-lumefantrine: the process of drug policy change in Zambia.(Case study)

Jan 29, 2008; Sipilanyambe, Naawa ... Authors: Naawa Sipilanyambe (corresponding author) [1]; Jonathon L Simon [2]; Pascalina Chanda [3]; Peter Olumese [4]; Robert W Snow [5,6]; Davidson H Hamer [2,7] Introduction Over 40 countries in sub-Saharan Africa have recently revised their national ...

Maternal peripheral blood level of IL-10 as a marker for inflammatory placental malaria.(Research)

Jan 29, 2008; Kabyemela, Edward R. ... Authors: Edward R Kabyemela (equal contributor) [1,2]; Atis Muehlenbachs (equal contributor) [1,3]; Michal Fried [1,3]; Jonathan D Kurtis [4]; Theonest K Mutabingwa [1,5]; Patrick E Duffy (corresponding author) [1,3] Background Placental malaria (PM) ...

Assessment of a treatment guideline to improve home management of malaria in children in rural south-west Nigeria.(Research)

Jan 29, 2008; Ajayi, Ikeoluwapo O. ... Authors: Ikeoluwapo O Ajayi (corresponding author) [1]; Catherine O Falade [2]; E Afolabi Bamgboye [1]; Ayo MJ Oduola [3]; Oladele O Kale [1] Background In Nigeria, the main strategy for reducing childhood morbidity and mortality is presumptive ...

Clinical malaria in African pregnant women.(Research)

Jan 30, 2008; Bardaji, Azucena ... Authors: Azucena Bardají [1,2]; Betuel Sigauque [2,3]; Laia Bruni [1]; Cleofé Romagosa [1,2]; Sergi Sanz [1]; Samuel Mabunda [4]; Inacio Mandomando [2,3]; John Aponte [1,2]; Esperança Sevene [5]; Pedro L Alonso [1,2]; Clara Menéndez (corresponding author) [1,2] ...

Malaria in central Vietnam: analysis of risk factors by multivariate analysis and classification tree models.(Research)(Survey)

Jan 30, 2008; Thang, Ngo Duc ... Authors: Ngo Duc Thang (corresponding author) [1]; Annette Erhart [2]; Niko Speybroeck [2,3]; Le Xuan Hung [1]; Le Khanh Thuan [1]; Cong Trinh Hung [1]; Pham Van Ky [4]; Marc Coosemans [2]; Umberto D'Alessandro [2] Background Since the launching of ...

Why don't health workers prescribe ACT? A qualitative study of factors affecting the prescription of artemether-lumefantrine.(Research)(artemisinin-based combination therapy)

Feb 05, 2008; Wasunna, Beatrice ... Authors: Beatrice Wasunna (corresponding author) [1,2]; Dejan Zurovac [2,3,4]; Catherine A Goodman [2,5]; Robert W Snow [2,3] Background The World Health Organization (WHO) recommends that efficacious artemisinin-based combination therapies (ACTs) ...

Prevalence of contraindications to mefloquine use among USA military personnel deployed to Afghanistan.(Research)

Feb 11, 2008; Nevin, Remington L. ... Authors: Remington L Nevin (corresponding author) [1]; Paul P Pietrusiak [2]; Jennifer B Caci [3] Background Malaria poses a continued threat to U.S. military personnel. At least 423 blood-smear confirmed cases of malaria were diagnosed among members ...

Sulphadoxine/pyrimethamine versus amodiaquine for treating uncomplicated childhood malaria in Gabon: A randomized trial to guide national policy.(Research)

Feb 12, 2008; Nsimba, Basile ... Authors: Basile Nsimba (corresponding author) [1]; Vincent Guiyedi [2]; Modeste Mabika-Mamfoumbi [2]; Jean Romain Mourou-Mbina [2]; Edgard Ngoungou [2]; Marielle Bouyou-Akotet [2]; Romaric Loembet [2]; Rémy Durand [3]; Jacques Le Bras [4]; Maryvonne Kombila [2] ...

Costs and effects of the Tanzanian national voucher scheme for insecticide-treated nets.(Research)

Feb 15, 2008; Mulligan, Jo-Ann ... Authors: Jo-Ann Mulligan (corresponding author) [1]; Joshua Yukich [2]; Kara Hanson [1] Background The cost-effectiveness of insecticide-treated nets (ITNs) in reducing morbidity and mortality is now well established [1, 2]. It is considered to be o­ne ...

Household cost of malaria overdiagnosis in rural Mozambique.(Research)

Feb 18, 2008; Hume, Jen CC. ... Authors: Jen CC Hume [1,2]; Guy Barnish [1]; Tara Mangal [1]; Luiz Armázio [3]; Elizabeth Streat [4]; Imelda Bates (corresponding author) [1] Background In sub-Saharan Africa over 70% of patients with suspected malaria diagnose and manage their ...

Quantitative urban classification for malaria epidemiology in sub-Saharan Africa.(Methodology)(Survey)

Feb 25, 2008; Siri, Jose G. ... Authors: Jose G Siri [1]; Kim A Lindblade [2]; Daniel H Rosen [2]; Bernard o­nyango [3]; John Vulule [3]; Laurence Slutsker [2]; Mark L Wilson (corresponding author) [1] Background The increasing urbanization of sub-Saharan Africa (SSA) may profoundly ...

Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine.(Research)

Feb 26, 2008; Barnadas, Celine ... Authors: Céline Barnadas (corresponding author) [1]; Magali Tichit [4]; Christiane Bouchier [4]; Arsène Ratsimbasoa [2]; Laurence Randrianasolo [2]; Rogelin Raherinjafy [3]; Martial Jahevitra [3]; Stéphane Picot [1]; Didier Ménard [3] Background ...

Malaria in rural Mozambique. Part I: Children attending the outpatient clinic.(Research)

Feb 26, 2008; Guinovart, Caterina ... Authors: Caterina Guinovart (corresponding author) [1,2]; Quique Bassat [1,2]; Betuel Sigaúque [2,3]; Pedro Aide [2,3]; Jahit Sacarlal [2,4]; Tacilta Nhampossa [2,3]; Azucena Bardají [1,2]; Ariel Nhacolo [2]; Eusébio Macete [2,5]; Inácio Mandomando [2,3]; John J Aponte ...

Malaria in rural Mozambique. Part II: children admitted to hospital.(Research)

Feb 26, 2008; Bassat, Quique ... Authors: Quique Bassat [1,2]; Caterina Guinovart (corresponding author) [1,2]; Betuel Sigaúque [2,3]; Pedro Aide [2,3]; Jahit Sacarlal [2,4]; Tacilta Nhampossa [2,3]; Azucena Bardají [1,2]; Ariel Nhacolo [2]; Eusébio Macete [2,5]; Inácio Mandomando [2,3]; John J Aponte ...

An experimental hut evaluation of Olyset.sup.[R] .sup.nets against anopheline mosquitoes after seven years use in Tanzanian villages.(Research)

Feb 28, 2008; Malima, Robert C. ... Authors: Robert C Malima [1]; Stephen M Magesa [1]; Patrick K Tungu [1]; Victor Mwingira [1]; Frank S Magogo [1]; Wema Sudi [1]; Frank W Mosha [2]; Christopher F Curtis [3]; Caroline Maxwell [1,3]; Mark Rowland (corresponding author) [3] Background ...

Immunologic activation of human syncytiotrophoblast by Plasmodium falciparum.(Research)

Feb 29, 2008; Lucchi, Naomi W. ... Authors: Naomi W Lucchi [1,2]; David S Peterson [1]; Julie M Moore (corresponding author) [1] Background It is estimated that annually approximately 2.2 billion people are exposed to the risk for Plasmodium falciparum malaria ...

Cytokine-associated neutrophil extracellular traps and antinuclear antibodies in Plasmodium falciparum infected children under six years of age.(Research)

Feb 29, 2008; Baker, Virginia S. ... Authors: Virginia S Baker (corresponding author) [1,7]; Godwin E Imade [2]; Norman B Molta [3]; Pallavi Tawde [1]; Sunday D Pam [2]; Michael O Obadofin [2]; Soloman A Sagay [2]; Daniel Z Egah [2]; Daniel Iya [2]; Bangmboye B Afolabi [4]; Murray Baker [5]; Karen Ford [6]; ...

Topography-derived wetness indices are associated with household-level malaria risk in two communities in the western Kenyan highlands.(Research)

Feb 29, 2008; Cohen, Justin M. ... Authors: Justin M Cohen (corresponding author) [1]; Kacey C Ernst [1]; Kim A Lindblade [2]; John M Vulule [3]; Chandy C John [4]; Mark L Wilson [1] Background Elevation has long been recognized to be associated with malaria [1] due to its association ...

Host choice and multiple blood feeding behaviour of malaria vectors and other anophelines in Mwea rice scheme, Kenya.(Research)

Feb 29, 2008; Muriu, Simon M. ... Authors: Simon M Muriu (corresponding author) [1,2]; Ephantus J Muturi [3]; Josephat I Shililu [1,4]; Charles M Mbogo [5]; Joseph M Mwangangi [1,5]; Benjamin G Jacob [3]; Lucy W Irungu [2]; Richard W Mukabana [2]; John I Githure [1]; Robert J Novak [3] ...

A census-weighted, spatially-stratified household sampling strategy for urban malaria epidemiology.(Research)

Feb 29, 2008; Siri, Jose G. ... Authors: Jose G Siri [1]; Kim A Lindblade (corresponding author) [2]; Daniel H Rosen [2]; Bernard o­nyango [3]; John M Vulule [3]; Laurence Slutsker [2]; Mark L Wilson [1] Background Malaria remains a critical health problem in sub-Saharan Africa (SSA), ...

Use of antenatal care, maternity services, intermittent presumptive treatment and insecticide treated bed nets by pregnant women in Luwero district, Uganda.(Research)

Mar 01, 2008; Kiwuwa, Mpungu S. ... Authors: Mpungu S Kiwuwa (corresponding author) (equal contributor) [1]; Patrobas Mufubenga (equal contributor) [2] Background Uganda is o­ne of the countries in sub-Saharan Africa with high maternal and neonatal morbidity and mortality rates. According ...

Concentration and purification by magnetic separation of the erythrocytic stages of all human Plasmodium species.(Methodology)

Mar 05, 2008; Ribaut, Clotilde ... Authors: Clotilde Ribaut [1]; Antoine Berry [2,3]; Séverine Chevalley [1]; Karine Reybier [1]; Isabelle Morlais [3]; Daniel Parzy [4]; Françoise Nepveu [1]; Françoise Benoit-Vical [2,5]; Alexis Valentin (corresponding author) [1] Background Falciparum ...

A highly conserved segmental duplication in the subtelomeres of Plasmodium falciparum chromosomes varies in copy number.(Research)

Mar 07, 2008; Mok, Bobo W. ... Authors: Bobo W Mok [1,2]; Ulf Ribacke [1,2]; Ellen Sherwood [3]; Mats Wahlgren (corresponding author) [1,2] Background Plasmodium falciparum , the causative agent of severe human malaria, carries a haploid nuclear genome of ...

No miRNA were found in Plasmodium and the o­nes identified in erythrocytes could not be correlated with infection.(Research)(micro ribonucleic acid)

Mar 10, 2008; Xue, Xiangyang ... Authors: Xiangyang Xue [1]; Qingfeng Zhang [1]; Yufu Huang [2]; Le Feng [1]; Weiqing Pan (corresponding author) [1,2] Background MicroRNAs (miRNAs), a newly discovered class of endogenous ~21 nucleotide regulatory non-coding small RNAs, ...

Real-time PCR/MCA assay using fluorescence resonance energy transfer for the genotyping of resistance related DHPS-540 mutations in Plasmodium falciparum.(Methodology)(polymerase chain reaction)

Mar 17, 2008; Mens, Petra F. ... Authors: Petra F Mens (corresponding author) [1,2]; Chantal van Overmeir [1]; Maryline Bonnet [3]; Jean-Claude Dujardin [1]; Umberto d'Alessandro [1] Background Malaria control is hampered by increasing spread of drug resistance [1]. Although ...

Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda.(Research)

Mar 20, 2008; Kilian, Albert ... Authors: Albert Kilian (corresponding author) [1,2]; Wilson Byamukama [3]; Olivier Pigeon [4]; Francis Atieli [5,6]; Stephan Duchon [7]; Chi Phan [8] Background In recent years the use of insecticide treated mosquito nets (ITN) and curtains has been ...

Process and effects of a community intervention o­n malaria in rural Burkina Faso: randomized controlled trial.(Research)

Mar 25, 2008; Kouyate, Bocar ... Authors: Bocar Kouyaté [1]; Florent Somé [1]; Albrecht Jahn [2]; Boubacar Coulibaly [1]; Jaran Eriksen [3]; Rainer Sauerborn [2]; Lars Gustafsson [3]; Göran Tomson [3]; Heiko Becher [2]; Olaf Mueller (corresponding author) [2] Background At least o­ne ...

Characterization of VAR2CSA-deficient Plasmodium falciparum -infected erythrocytes selected for adhesion to the BeWo placental cell line.(Research)(chondroitin sulphate A)

Mar 26, 2008; Yosaatmadja, Francisca ... Authors: Francisca Yosaatmadja [1]; Katherine T Andrews [2,3]; Michael F Duffy [1]; Graham V Brown [1,4]; James G Beeson [5]; Stephen J Rogerson (corresponding author) [1] Background Almost half of the world's population is exposed to the risk of ...

Bionomics of Anopheles latens in Kapit, Sarawak, Malaysian Borneo in relation to the transmission of zoonotic simian malaria parasite Plasmodium knowlesi.(Research)

Mar 31, 2008; Tan, Cheong H. ... Authors: Cheong H Tan [1,2]; Indra Vythilingam (corresponding author) [1]; Asmad Matusop [3]; Seng T Chan [1]; Balbir Singh [2] Background Malaria parasites in Peninsular Malaysian monkeys were first reported in 1908 [1], but o­nly gained prominence in ...

Guidelines and mindlines: why do clinical staff over-diagnose malaria in Tanzania? A qualitative study.(Research)

Apr 02, 2008; Chandler, Clare IR. ... Authors: Clare IR Chandler (corresponding author) [1]; Caroline Jones [1]; Gloria Boniface [2]; Kaseem Juma [2]; Hugh Reyburn [1,2]; Christopher JM Whitty [1] Background Whilst malaria remains the most important diagnosis in children in most of ...

Can changes in malaria transmission intensity explain prolonged protection and contribute to high protective efficacy of intermittent preventive treatment for malaria in infants?(Research)

Apr 03, 2008; Gosling, Roly D. ... Authors: Roly D Gosling (corresponding author) [1]; Azra C Ghani [2]; Jaqueline L Deen [3]; Lorenz von Seidlein [1]; Brian M Greenwood [1]; Daniel Chandramohan [1] Background Intermittent preventive treatment of infants (IPTi) is the administration of ...

Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: Up-dated baseline data from randomized and multi-site clinical trials.(Research)

Apr 04, 2008; Menard, Didier ... Authors: Didier Ménard (corresponding author) [1]; Arsène Ratsimbasoa [2]; Milijaona Randrianarivelojosia [1]; Léon-Paul Rabarijaona [2]; Lucie Raharimalala [1]; Olivier Domarle [3]; Laurence Randrianasolo [2]; Arthur Randriamanantena [2]; Martial Jahevitra [1]; Valérie ...

Imported malaria in a cosmopolitan European city: A mirror image of the world epidemiological situation.(Research)

Apr 08, 2008; Millet, Juan Pablo ... Authors: Juan Pablo Millet (corresponding author) [1,2]; Patricia Garcia de Olalla [1]; Paloma Carrillo-Santisteve [1]; Joaquim Gascón [3]; Begoña Treviño [4]; José Muñoz [3]; Jordi Gómez i Prat [4]; Juan Cabezos [4]; Anna González Cordón [2,3]; Joan A Caylà [1] ...

Clinically uncomplicated Plasmodium falciparum malaria with high schizontaemia: A case report.(Case report)(Case study)

Apr 11, 2008; Lwin, Khin Maung ... Authors: Khin Maung Lwin [1,2]; Elizabeth A Ashley [1,2,3]; Stephane Proux [1]; Kamolrat Silamut [2]; François Nosten [1,2,3]; Rose McGready (corresponding author) [1,2,3] Background The 2006 WHO malaria treatment guidelines [1] laid out in a user ...

Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso.(Research)

Apr 17, 2008; Mandi, Germain ... Authors: Germain Mandi [1]; Frank P Mockenhaupt [2]; Boubacar Coulibaly [1]; Peter Meissner [3]; Olaf Müller (corresponding author) [3] Background In sub-Saharan African (SSA), the basis of malaria control remains early diagnosis and prompt treatment ...

Mosquito abundance, bed net coverage and other factors associated with variations in sporozoite infectivity rates in four villages of rural Tanzania.(Research)

Apr 18, 2008; Kweka, Eliningaya J. ... Authors: Eliningaya J Kweka (corresponding author) [1,2,3]; Watoky MM Nkya [2,3]; Aneth M Mahande [1,2,3]; Charles Assenga [3]; Franklin W Mosha [2,3]; Ester E Lyatuu [1]; Charles P Massenga [1]; Edwin M Nyale [3]; Stephen B Mwakalinga [2,3,4]; Asanterabi Lowassa ...

Socio-economic status is inversely related to bed net use in Gabon.(Research)

Apr 18, 2008; Goesch, Julia N. ... Authors: Julia N Goesch (corresponding author) [1,2]; Norbert G Schwarz [1,2]; Marie-Luise Decker [1,2]; Sunny Oyakhirome [1,2]; Lea B Borchert [1,2]; Ulrich D Kombila [1,2]; Marc Poetschke [1,2]; Bertrand Lell [1,2]; Saadou Issifou [1,2]; Peter G Kremsner [1,2]; Martin ...

The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus sulphadoxine-pyrimethamine against falciparum malaria in Papua New Guinea.(Research)

Apr 19, 2008; Marfurt, Jutta ... Authors: Jutta Marfurt [1,3]; Ivo Müller [2]; Albert Sie [2]; Olive Oa [2,4]; John C Reeder [2,5]; Thomas A Smith [1,6]; Hans-Peter Beck [1,7]; Blaise Genton (corresponding author) [1,8] Background The effectiveness of the most widely used first-line ...

Investigation of a novel approach to scoring Giemsa-stained malaria-infected thin blood films.(Methodology)

Apr 21, 2008; Proudfoot, Owen ... Authors: Owen Proudfoot (corresponding author) [1]; Nathan Drew [2]; Anja Scholzen [3]; Sue Xiang [3]; Magdalena Plebanski [3] Background When conducting blood-stage malaria trials involving live malaria challenges in mice, frequent assessment of their ...

Role of Plasmodium falciparum thrombospondin-related anonymous protein in host-cell interactions.(Research)

Apr 22, 2008; Akhouri, Reetesh Raj ... Authors: Reetesh Raj Akhouri [1,2]; Ashwani Sharma [1]; Pawan Malhotra (corresponding author) [2]; Amit Sharma (corresponding author) [1] Background Malaria is a major parasitic disease that claims more than two million lives and causes more than 500 ...

Natural relapses in vivax malaria induced by Anopheles mosquitoes.(Research)

Apr 22, 2008; Hulden, Lena ... Authors: Lena Huldén (corresponding author) [1]; Larry Huldén [2]; Kari Heliövaara [1] Background It has long been known that vivax malaria causes relapses in a variable degree. The malarial relapse including a pre-erythrocytic stage ...

Enhanced detection of gametocytes by magnetic deposition microscopy predicts higher potential for Plasmodium falciparum transmission.(Research)

Apr 25, 2008; Karl, Stephan ... Authors: Stephan Karl [1]; Makindi David [2]; Lee Moore [3]; Brian T Grimberg [4]; Pascal Michon [2]; Ivo Mueller [2]; Maciej Zborowski (corresponding author) [3]; Peter A Zimmerman (corresponding author) [4] Background Reliable malaria diagnosis ...

Towards a sterile insect technique field release of Anopheles arabiensis mosquitoes in Sudan: Irradiation, transportation, and field cage experimentation.(Methodology)

Apr 25, 2008; Helinski, Michelle EH. ... Authors: Michelle EH Helinski (corresponding author) (equal contributor) [1,2]; Mo'awia M Hassan (equal contributor) [3]; Waleed M El-Motasim [4]; Colin A Malcolm [1,5]; Bart GJ Knols [2]; Badria El-Sayed [3] Background Application of the Sterile ...

Clinically immune hosts as a refuge for drug-sensitive malaria parasites.(Research)

Apr 25, 2008; Klein, Eili Y. ... Authors: Eili Y Klein [1,2]; David L Smith [3]; Maciej F Boni [1,2,4]; Ramanan Laxminarayan (corresponding author) [1,4] Background Malaria is the leading cause of death in children under five in sub-Saharan Africa [1]. Prompt treatment with effective ...

The severity of malarial anaemia in Plasmodium chabaudi infections of BALB/c mice is determined independently of the number of circulating parasites.(Research)

Apr 25, 2008; Lamb, Tracey J. ... Authors: Tracey J Lamb [1,2]; Jean Langhorne (corresponding author) [1] Background Severe malarial anaemia (SMA) is a major factor contributing to malarial morbidity in humans (for review see [1, 2]) and is a significant pathological feature of most ...

Evaluation of an operational malaria outbreak identification and response system in Mpumalanga Province, South Africa.(Methodology)

Apr 27, 2008; Coleman, Marlize ... Authors: Marlize Coleman [1]; Michael Coleman (corresponding author) [2,3]; Aaron M Mabuza [4]; Gerdalize Kok [4]; Maureen Coetzee [5,6]; David N Durrheim [7] Background Malaria is the most important parasitic and vector borne disease globally ...

Multiple origins of resistance-conferring mutations in Plasmodium vivax dihydrofolate reductase.(Research)

Apr 28, 2008; Hawkins, Vivian N. ... Authors: Vivian N Hawkins [1]; Alyson Auliff [2]; Surendra Kumar Prajapati [3]; Kanchana Rungsihirunrat [4]; Hapuarachchige C Hapuarachchi [5]; Amanda Maestre [6]; Michael T O'Neil [2,7]; Qin Cheng [2]; Hema Joshi [3]; Kesara Na-Bangchang [8]; Carol Hopkins Sibley ...

Evaluation of FRET real-time PCR assay for rapid detection and differentiation of Plasmodium species in returning travellers and migrants.(Methodology)(Polymerase chain reaction)

Apr 28, 2008; Safeukui, Innocent ... Authors: Innocent Safeukui (corresponding author) [1,5]; Pascal Millet [1,2,3]; Sébastien Boucher [1]; Laurence Melinard [1]; Frédéric Fregeville [2]; Marie-Catherine Receveur [4]; Thierry Pistone [4]; Pierre Fialon [2]; Philippe Vincendeau [1,2]; Hervé Fleury [1]; Denis ...

Determination of nitric oxide metabolites, nitrate and nitrite, in Anopheles culicifacies mosquito midgut and haemolymph by anion exchange high-performance liquid chromatography: plausible mechanism of refractoriness.(Methodology)

Apr 28, 2008; Sharma, Arun ... Authors: Arun Sharma (corresponding author) [1]; Kamaraju Raghavendra [2]; Tridibesh Adak [3]; Aditya P Dash [4] Background Potential control efforts for malaria mainly include vaccine development, vector control and development of new anti-malarial ...

Cost-effectiveness analysis of insecticide-treated net distribution as part of the Togo Integrated Child Health Campaign.(Research)

Apr 29, 2008; Mueller, Dirk H. ... Authors: Dirk H Mueller (corresponding author) [1]; Virginia Wiseman [1]; Dankom Bakusa [2]; Kodjo Morgah [3]; Aboudou Daré [4]; Potougnima Tchamdja [5] Background Evidence o­n the effectiveness of insecticide-treated nets (ITNs) to prevent malaria in ...

Distribution of knock-down resistance mutations in Anopheles gambiae molecular forms in west and west-central Africa.(Research)

Apr 29, 2008; Santolamazza, Federica ... Authors: Federica Santolamazza [1,2]; Maria Calzetta [1,2]; Josiane Etang [3]; Elena Barrese [1,2]; Ibrahima Dia [4]; Adalgisa Caccone [5]; Martin J Donnelly [6]; Vincenzo Petrarca [1,7]; Frederic Simard [3]; Joao Pinto [8]; Alessandra della Torre (corresponding author) ...

Impact of community-based presumptive chloroquine treatment of fever cases o­n malaria morbidity and mortality in a tribal area in Orissa State, India.(Research)

May 05, 2008; Das, Lalit K. ... Authors: Lalit K Das (corresponding author) [1]; Purushothaman Jambulingam [1]; Candasamy Sadanandane [1] Background The present strategies for malaria control vary depending up o­n the epidemiological situations. Until a safe, effective and affordable ...

Heterogeneous distribution of Plasmodium falciparum drug resistance haplotypes in subsets of the host population.(Research)

May 06, 2008; Schoepflin, Sonja ... Authors: Sonja Schoepflin [1]; Jutta Marfurt [1]; Mary Goroti [2]; Moses Baisor [2]; Ivo Mueller [2]; Ingrid Felger (corresponding author) [1] Background The emergence of drug resistance poses a major problem for malaria control. Research has focused ...

Models for short term malaria prediction in Sri Lanka.(Research)

May 06, 2008; Briet, Olivier JT. ... Authors: Olivier JT Briët (corresponding author) [1,2]; Penelope Vounatsou [2]; Dissanayake M Gunawardena [3]; Gawrie NL Galappaththy [4]; Priyanie H Amerasinghe [5] Background Malaria has been a major public health problem in Sri Lanka [1] until ...

Temporal correlation between malaria and rainfall in Sri Lanka.(Research)

May 06, 2008; Briet, Olivier JT. ... Authors: Olivier JT Briët (corresponding author) [1,2]; Penelope Vounatsou [2]; Dissanayake M Gunawardena [3]; Gawrie NL Galappaththy [4]; Priyanie H Amerasinghe [5] Background Malaria is a complex disease and its transmission and prevalence is ...

Atelier paludisme: an international malaria training course held in Madagascar.(Commentary)(Brief article)

May 09, 2008; Domarle, Olivier ... Authors: Olivier Domarle [1]; Milijaona Randrianarivelojosia (corresponding author) [1]; Jean-Bernard Duchemin [1,2]; Vincent Robert [1,3]; Frédéric Ariey [1,4] Background Malaria control programmes are based o­n several strategies, which work best when ...

Timing of intermittent preventive treatment for malaria during pregnancy and the implications of current policy o­n early uptake in north-east Tanzania.(Research)

May 09, 2008; Anders, Katherine ... Authors: Katherine Anders (corresponding author) [1]; Tanya Marchant [1]; Pili Chambo [2]; Pasiens Mapunda [3]; Hugh Reyburn [1,2] Background Malaria infection during pregnancy has adverse consequences for both the woman and foetus, accounting for an ...

Malaria and obesity: obese mice are resistant to cerebral malaria.(Research)

May 19, 2008; Robert, Vincent ... Authors: Vincent Robert (corresponding author) [1,2]; Catherine Bourgouin [3]; Delphine Depoix [2]; Catherine Thouvenot [3]; Marie-Noëlle Lombard [2]; Philippe Grellier [2] Introduction Obesity, mainly characterized by an excess of adipose tissue, is ...

Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India.(Research)

May 19, 2008; Jain, Vidhan ... Authors: Vidhan Jain [1]; Henry B Armah [2]; Jon E Tongren [3]; Renée M Ned [3]; Nana O Wilson [2]; Sara Crawford [3]; Pradeep K Joel [4]; Mrigendra P Singh [1]; Avinash C Nagpal [4]; AP Dash [4]; Venkatachalam Udhayakumar [3]; Neeru Singh [1]; Jonathan K Stiles ...

The microneme proteins CTRP and SOAP are not essential for Plasmodium berghei ookinete to oocyst transformation in vitro in a cell free system.(Research)

May 19, 2008; Nacer, Adela ... Authors: Adéla Nacer [1]; Ann Underhill [1]; Hilary Hurd (corresponding author) [1] Background Ever since the early 1900s, an appreciation of the role that anopheline mosquitoes play in the transmission of malaria [1] has directed disease control ...

A regulatable transgene expression system for cultured Plasmodium falciparum parasites.(Methodology)

May 20, 2008; Epp, Christian ... Authors: Christian Epp [1,2]; Dima Raskolnikov [1]; Kirk W Deitsch (corresponding author) [1] Background Over a decade ago, the first transfections and genetic manipulations of malaria parasites were accomplished [1, 2, 3], ushering in a new era in ...

Retention and efficacy of long-lasting insecticide-treated nets distributed in eastern Sudan: a two-step community-based study.(Research)

May 20, 2008; Hassan, Saad El-Din Hussein ... Authors: Saad El-Din Hussein Hassan (corresponding author) [1]; Elfatih M Malik [2]; Somia I Okoued [3]; Elsadig M Eltayeb [4] Background In Sudan, malaria is a major public health problem, topping the list of the main causes of morbidity, mortality ...

Cost of increasing access to artemisinin combination therapy: the Cambodian experience.(Research)

May 20, 2008; Yeung, Shunmay ... Authors: Shunmay Yeung (corresponding author) [1,2]; Wim Van Damme [3]; Duong Socheat [4]; Nicholas J White [2]; Anne Mills [1] Background Artemisinin combination therapies (ACTs) are now the officially recommended treatment for Plasmodium ...

Escalating Plasmodium falciparum antifolate drug resistance mutations in Macha, rural Zambia.(Research)

May 21, 2008; Mkulama, Mtawa AP. ... Authors: Mtawa AP Mkulama [1]; Sandra Chishimba [1]; Jay Sikalima [1]; Petrica Rouse [2]; Philip E Thuma [1]; Sungano Mharakurwa (corresponding author) [1,2] Background Malaria kills an estimated 0.7 to 2.7 million people, of which 75% are African ...

Interactions between dendritic cells and CD4.sup.+ .sup.T cells during Plasmodium infection.(Research)

May 21, 2008; Ocana-Morgner, Carlos ... Authors: Carlos Ocaña-Morgner [1,2]; Kurt A Wong [1]; Ana Rodriguez (corresponding author) [1] Background Dendritic cells (DCs) are antigen-presenting cells (APC) that play a central role in both innate and adaptive immune responses. To initiate T ...

Performance and usefulness of the Hexagon rapid diagnostic test in children with asymptomatic malaria living in the Mount Cameroon region.(Research)

May 22, 2008; Wanji, Samuel ... Authors: Samuel Wanji (corresponding author) [1,2]; Helen K Kimbi [3]; Joan E Eyong [1,3]; Nicholas Tendongfor [1,2]; Judith L Ndamukong [1,3] Background The cosmopolitan populations of some areas of the Mt. Cameroon region are often infected with ...

A structural annotation resource for the selection of putative target proteins in the malaria parasite.(Methodology)

May 23, 2008; Joubert, Yolandi ... Authors: Yolandi Joubert [1]; Fourie Joubert (corresponding author) [1] Background Malaria parasite resistance to therapeutic drugs such as sulfadoxine and pyrimethamine have increased significantly during the past two decades [2, 3]. Following the ...

Antipyretic effect of ibuprofen in Gabonese children with uncomplicated falciparum malaria: a randomized, double-blind, placebo-controlled trial.(Research)

May 26, 2008; Matsiegui, Pierre-Blaise ... Authors: Pierre-Blaise Matsiégui (equal contributor) [1,2]; Michel A Missinou (equal contributor) [1,2]; Magdalena Necek [1,2]; Elie Mavoungou (corresponding author) [1]; Saadou Issifou [1]; Bertrand Lell [1,2]; Peter G Kremsner [1,2] Background Fever ...

Reduced susceptibility to pyrethroid insecticide treated nets by the malaria vector Anopheles gambiae s.l . in western Uganda.(Research)

May 26, 2008; John, Rubaihayo ... Authors: Rubaihayo John (corresponding author) [1]; Tukesiga Ephraim [2]; Abaasa Andrew [3] Background In Africa, malaria is still the leading cause of childhood and maternal ill health and death [1]. In Uganda the burden of malaria is unacceptably ...

Substandard anti-malarial drugs in Burkina Faso.(Research)

May 27, 2008; Tipke, Maike ... Authors: Maike Tipke (corresponding author) [1]; Salou Diallo [2]; Boubacar Coulibaly [2]; Dominic Störzinger [3]; Torsten Hoppe-Tichy [3]; Ali Sie [2]; Olaf Müller [1] Background Malaria remains the globally most important parasitic disease. Out of ...

Plasmodium vivax trophozoites insensitive to chloroquine.(Research)

May 27, 2008; Sharrock, Wesley W. ... Authors: Wesley W Sharrock (equal contributor) [1]; Rossarin Suwanarusk (equal contributor) [1,2]; Usa Lek-Uthai [3]; Michael D Edstein [4]; Varakorn Kosaisavee [3]; Thomas Travers [4]; Anchalee Jaidee [5]; Kanlaya Sriprawat [5]; Ric N Price [1,6]; François Nosten ...

Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru.(Research)

May 27, 2008; Chenet, Stella M. ... Authors: Stella M Chenet [1]; OraLee H Branch [2]; Ananias A Escalante [3]; Carmen M Lucas [1]; David J Bacon (corresponding author) [1,4] Background Vaccine design for Plasmodium falciparum is hindered by polymorphisms in certain ...

Access to artemisinin combination therapy for malaria in remote areas of Cambodia.(Research)

May 29, 2008; Yeung, Shunmay ... Authors: Shunmay Yeung (corresponding author) [1,2]; Wim Van Damme [3]; Doung Socheat [4]; Nicholas J White [2]; Anne Mills [1] Background Artemisinin combination therapies (ACTs) are now the official drug of choice in most malaria-endemic countries. ...

Acute pancreatitis and subdural haematoma in a patient with severe falciparum malaria: Case report and review of literature.(Case report)(Case study)

May 30, 2008; Seshadri, Pratibha ... Authors: Pratibha Seshadri [1]; Anand Vimal Dev [1]; Surekha Viggeswarpu [1]; Sowmya Sathyendra [1]; John Victor Peter (corresponding author) [1] Background Falciparum malaria is a common disorder in the tropics associated with myriad complications ...

Markets, voucher subsidies and free nets combine to achieve high bed net coverage in rural Tanzania.(Research)

Jun 02, 2008; Khatib, Rashid A. ... Authors: Rashid A Khatib (corresponding author) [1]; Gerry F Killeen [1,3]; Salim MK Abdulla [1]; Elizeus Kahigwa [1]; Peter D McElroy [4]; Rene PM Gerrets [5]; Hassan Mshinda [1]; Alex Mwita [6]; S Patrick Kachur [2] Background It is estimated that ...

Malaria transmission pattern resilience to climatic variability is mediated by insecticide-treated nets.(Research)

Jun 02, 2008; Chaves, Luis Fernando ... Authors: Luis Fernando Chaves (corresponding author) [1]; Akira Kaneko [2,3]; George Taleo [4]; Mercedes Pascual [1]; Mark L Wilson [1,5] Background Qualitative changes in the dynamics of populations, or regime shifts, are common phenomena across all ...

Comparison of male reproductive success in malaria-refractory and susceptible strains of Anopheles gambiae.(Research)

Jun 05, 2008; Voordouw, Maarten J. ... Authors: Maarten J Voordouw (corresponding author) [1,2,3]; Jacob C Koella (equal contributor) [2]; Hilary Hurd (equal contributor) [3] Background Parasitic infections exert strong selection o­n the immune systems of their hosts. However, evolution and ...

A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes.(Research)(Report)

Jun 05, 2008; Bengtsson, Dominique ... Authors: Dominique Bengtsson [1]; Kordai M Sowa [1]; Ali Salanti [1]; Anja TR Jensen [1]; Louise Joergensen [1]; Louise Turner [1]; Thor G Theander [1]; David E Arnot (corresponding author) [1,2] Background Plasmodium falciparum ...

The insecticide resistance status of malaria vectors in the Mekong region.(Research)

Jun 05, 2008; Van Bortel, Wim ... Authors: Wim Van Bortel (corresponding author) [1]; Ho Dinh Trung [2]; Le Khanh Thuan [2]; Tho Sochantha [3]; Duong Socheat [3]; Chalao Sumrandee [4]; Visut Baimai [4]; Kalouna Keokenchanh [5]; Phompida Samlane [5]; Patricia Roelants [1]; Leen Denis [1]; Katrijn ...

Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA.(Research)(chondroitin sulfate A)

Jun 06, 2008; Resende, Mafalda ... Authors: Mafalda Resende [1]; Morten A Nielsen [1]; Madeleine Dahlbäck [1]; Sisse B Ditlev [1]; Pernille Andersen [2]; Adam F Sander [1]; Nicaise T Ndam [3]; Thor G Theander [1]; Ali Salanti (corresponding author) [1] Background PAM (Pregnancy ...

The resting sites and blood-meal sources of Anopheles minimus in Taiwan.(Research)

Jun 09, 2008; Chang, Mei-Chun ... Authors: Mei-Chun Chang [1]; Hwa-Jen Teng (corresponding author) [1]; Chen-Fu Chen [1]; Yung-Chen Chen [1]; Chian-Ren Jeng [2] Background Malaria is documented to have been prevalent throughout much of Taiwan in the19th ...

Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children.(Research)(Clinical report)

Jun 11, 2008; Maiteki-Sebuguzi, Catherine ... Authors: Catherine Maiteki-Sebuguzi [1]; Prasanna Jagannathan [2]; Vincent M Yau [3]; Tamara D Clark [2]; Denise Njama-Meya [1]; Bridget Nzarubara [1]; Ambrose O Talisuna [4]; Moses R Kamya [1]; Philip J Rosenthal [2]; Grant Dorsey [2]; Sarah G Staedke (corresponding ...

Monitoring antimalarial safety and tolerability in clinical trials: A case study from Uganda.(Case study)(Report)

Jun 11, 2008; Staedke, Sarah G. ... Authors: Sarah G Staedke (corresponding author) [1,2]; Prasanna Jagannathan [3]; Adoke Yeka [4]; Hasifa Bukirwa [4]; Kristin Banek [4]; Catherine Maiteki-Sebuguzi [5]; Tamara D Clark [3]; Bridget Nzarubara [5]; Denise Njama-Meya [5]; Arthur Mpimbaza [5]; Philip J ...

Full blood count and haemozoin-containing leukocytes in children with malaria: diagnostic value and association with disease severity.(Research)

Jun 12, 2008; Hanscheid, Thomas ... Authors: Thomas Hänscheid [1,2]; Matthias Längin [1,3]; Bertrand Lell [1,3]; Marc Pötschke [1,3]; Sunny Oyakhirome [1,3]; Peter G Kremsner [1,3]; Martin P Grobusch (corresponding author) [1,4] Background Malaria is known to cause several changes in ...

A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma.(Methodology)

Jun 12, 2008; Cham, Gerald KK. ... Authors: Gerald KK Cham (corresponding author) [1]; Jonathan Kurtis [2]; John Lusingu [3]; Thor G Theander [1]; Anja TR Jensen [1]; Louise Turner [1] Background The hope of developing a vaccine against malaria is based o­n evidence that clinical ...

One-year delayed effect of fog o­n malaria transmission: a time-series analysis in the rain forest area of Mengla County, south-west China.(Research)(Clinical report)

Jun 19, 2008; Tian, Linwei ... Authors: Linwei Tian (corresponding author) (equal contributor) [1]; Yan Bi (equal contributor) [2]; Suzanne C Ho [1,3]; Wenjie Liu [4]; Song Liang [5]; William B Goggins [6]; Emily YY Chan [3]; Shuisen Zhou [7]; Joseph JY Sung [1] Background Malaria ...

Spatially-explicit risk profiling of Plasmodium falciparum infections at a small scale: a geostatistical modelling approach.(Research)(Clinical report)

Jun 23, 2008; Silue, Kigbafori D. ... Authors: Kigbafori D Silué (equal contributor) [1,2]; Giovanna Raso (corresponding author) (equal contributor) [3,4]; Ahoua Yapi [1]; Penelope Vounatsou [5]; Marcel Tanner [5]; Eliézer K N'Goran [1,2]; Jürg Utzinger [5] Background Malaria remains a ...

Polymorphism patterns in Duffy-binding protein among Thai Plasmodium vivax isolates.(Research)

Jun 26, 2008; Gosi, Panita ... Authors: Panita Gosi [1,2]; Srisin Khusmith (corresponding author) [1]; Thareerat Khalambaheti [1]; David E Lanar [3]; Kurt E Schaecher [2]; Mark M Fukuda [2]; Scott R Miller [3] Background Molecular mechanisms of invasion by Plasmodium vivax ...

Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection.(Case report)

Jun 26, 2008; Nagao, Yoshiro ... Authors: Yoshiro Nagao (corresponding author) [1]; Masako Kimura-Sato [2]; Porntip Chavalitshewinkoon-Petmitr [1]; Supatra Thongrungkiat [1]; Polrat Wilairatana [1]; Takafumi Ishida [2]; Peerapan Tan-ariya [3]; J Brian de Souza [4]; Srivicha Krudsood [1]; Sornchai ...

Median knock-down time as a new method for evaluating insecticide-treated textiles for mosquito control.(Methodology)

Jun 27, 2008; Skovmand, Ole ... Authors: Ole Skovmand (corresponding author) [1]; Julien Bonnet [2]; Olivier Pigeon [3]; Vincent Corbel [2] Background Long-Lasting Insecticide-treated Nets (LNs) and tarpaulins have been developed for controlling malaria vectors. Among these are ...

Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique.(Research)(Clinical report)

Jul 01, 2008; Enosse, Sonia ... Authors: Sonia Enosse (corresponding author) [1,2]; Pascal Magnussen [3]; Fatima Abacassamo [2]; Xavier Gómez-Olivé [2,4]; Anita M Rønn [5]; Ricardo Thompson [1,2]; Michael Alifrangis [5] Background Large scale prevalence of Plasmodium ...

SURFIN.sub.4.1 , a schizont-merozoite associated protein in the SURFIN family of Plasmodium falciparum.(Research)(Clinical report)

Jul 01, 2008; Mphande, Fingani A. ... Authors: Fingani A Mphande [1]; Ulf Ribacke [1]; Osamu Kaneko [2]; Fred Kironde [3]; Gerhard Winter [1,4]; Mats Wahlgren (corresponding author) [1] Background The erythrocytic life cycle of Plasmodium falciparum is characterized by ...

Congenital Plasmodium falciparum infection in neonates in Muheza District, Tanzania.(Research)(Clinical report)

Jul 03, 2008; Mwangoka, Grace W. ... Authors: Grace W Mwangoka (corresponding author) [1]; Sharadhuli I Kimera [2]; Leonard EG Mboera [3] Background About 300,000 foetal and infants deaths and 2,500 deaths of pregnant women are attributable to malaria [1]. Poor outcome for both mother and ...

Evaluation of light microscopy and rapid diagnostic test for the detection of malaria under operational field conditions: a household survey in Ethiopia.(Research)(Survey)

Jul 03, 2008; Endeshaw, Tekola ... Authors: Tekola Endeshaw [1]; Teshome Gebre [1]; Jeremiah Ngondi (corresponding author) [2,4]; Patricia M Graves [2]; Estifanos B Shargie [1]; Yeshewamebrat Ejigsemahu [1]; Berhan Ayele [1]; Gedeon Yohannes [1]; Tesfaye Teferi [1]; Ayenew Messele [1]; Mulat Zerihun [1]; ...

Recent reduction in the water level of Lake Victoria has created more habitats for Anopheles funestus.(Research)

Jul 03, 2008; Minakawa, Noboru ... Authors: Noboru Minakawa (corresponding author) [1]; Gorge Sonye [2]; Gabriel O Dida [3]; Kyoko Futami [1]; Satoshi Kaneko [1] Background Satellite radar altimeter data [1] indicate that the water level of Lake Victoria in May 1998 was 1.06 m above its ...

Population structure of the malaria vector Anopheles moucheti in the equatorial forest region of Africa.(Research)

Jul 04, 2008; Antonio-Nkondjio, Christophe ... Authors: Christophe Antonio-Nkondjio (corresponding author) [1]; Cyrille Ndo [1,3]; Pierre Kengne [2]; Louis Mukwaya [4]; Parfait Awono-Ambene [1]; Didier Fontenille [2]; Frédéric Simard [1,2] Background Malaria remains o­ne of the world's major health ...

Antibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in India.(Research)

Jul 04, 2008; Lucchi, Naomi W. ... Authors: Naomi W Lucchi [1]; Jon Eric Tongren [1]; Vidhan Jain [2]; Avinash C Nagpal [3]; Christian W Kauth [4]; Ute Woehlbier [4]; Hermann Bujard [4]; Aditya P Dash [5]; Neeru Singh [2]; Jonathan K Stiles [6]; Venkatachalam Udhayakumar (corresponding author) [1,7] ...

No PfATPase6 S769N mutation found in Plasmodium falciparum isolates from China.(Research)

Jul 08, 2008; Zhang, Guoqing ... Authors: Guoqing Zhang [1]; Yayi Guan [1]; Bin Zheng [1]; Song Wu [1]; Linhua Tang (corresponding author) [1] Background China has been severely afflicted by falciparum malaria. In 1954, falciparum malaria cases totaled about 4.18 million in the whole ...

Antimalarial drug use in general populations of tropical Africa.(Research)(Clinical report)

Jul 08, 2008; Gardella, Florence ... Authors: Florence Gardella [1,2]; Serge Assi [3]; Fabrice Simon [4]; Hervé Bogreau [1,2]; Teunis Eggelte [5]; Fatou Ba [6]; Vincent Foumane [7]; Marie-Claire Henry [8]; Pélagie Traore Kientega [8]; Léonardo Basco [7]; Jean-François Trape [6,2]; Richard Lalou [9]; Maryse ...

Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season o­n the incidence of clinical malaria in children in Mali.(Research)(Clinical report)

Jul 08, 2008; Dicko, Alassane ... Authors: Alassane Dicko (corresponding author) [1,2]; Issaka Sagara [1]; Mahamadou S Sissoko [1]; Ousmane Guindo [1]; Abdoulbaki I Diallo [1]; Mamady Kone [1]; Ousmane B Toure [1]; Massambou Sacko [2]; Ogobara K Doumbo [1] Background Malaria is o­ne of ...

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials.(Research)(Clinical report)

Jul 09, 2008; Okell, Lucy C. ... Authors: Lucy C Okell (corresponding author) [1]; Chris J Drakeley [1]; Azra C Ghani [2]; Teun Bousema [3]; Colin J Sutherland [1] Background With resistance to chloroquine and sulphadoxine-pyrimethamine well-established in many malaria endemic ...

The usefulness of a new rapid diagnostic test, the First Response.sup.[R] .sup.Malaria Combo (pLDH/HRP2) card test, for malaria diagnosis in the forested belt of central India.(Research)(Clinical report)

Jul 11, 2008; Bharti, Praveen K. ... Authors: Praveen K Bharti [1]; Nipun Silawat [1]; Pushpendra P Singh [1]; Mrigendra P Singh [1]; Manmohan Shukla [1]; Gyan Chand [2]; Aditya P Dash [3]; Neeru Singh (corresponding author) [1,2] Background Malaria is a major public health problem in ...

Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with o­ne year follow-up.(Research)(Clinical report)

Jul 11, 2008; Adjei, George O. ... Authors: George O Adjei [1,4]; Jorgen AL Kurtzhals [4]; o­nike P Rodrigues [1]; Michael Alifrangis [4]; Lotte CG Hoegberg [4]; Emmanuel D Kitcher [3]; Ebenezer V Badoe [1]; Roberta Lamptey [2]; Bamenla Q Goka (corresponding author) [1] Background ...

Evaluation of immunoglobulin purification methods and their impact o­n quality and yield of antigen-specific antibodies.(Methodology)

Jul 14, 2008; Bergmann-Leitner, Elke S. ... Authors: Elke S Bergmann-Leitner (corresponding author) [1]; Ryan M Mease [1]; Elizabeth H Duncan [1]; Farhat Khan [1]; John Waitumbi [2]; Evelina Angov [1] Background Serological analysis of humoral responses is crucial for vaccine evaluation as well ...

Performance of self-diagnosis and standby treatment of malaria in international oilfield service employees in the field.(Research)

Jul 14, 2008; Roukens, Anna H. ... Authors: Anna H Roukens [1]; Johannes Berg [2]; Alex Barbey [3]; Leo G Visser (corresponding author) [1] Background Every year, Plasmodium falciparum infects 300 to 500 million persons, and kills between o­ne and two million ....

MalHaploFreq : A computer programme for estimating malaria haplotype frequencies from blood samples.(Methodology)

Jul 15, 2008; Hastings, Ian M. ... Authors: Ian M Hastings (corresponding author) [1]; Thomas A Smith [2] Background The identification of molecular markers (mutations) associated with drug resistance in P. falciparum , and the ability to detect these markers in the ...

Competency of Anopheles stephensi mysorensis strain for Plasmodium vivax and the role of inhibitory carbohydrates to block its sporogonic cycle.(Research)

Jul 15, 2008; Basseri, Hamid R. ... Authors: Hamid R Basseri (corresponding author) [1]; Soghra Doosti [1]; Kamran Akbarzadeh [1]; Mehdi Nateghpour [1]; Miranda MA Whitten [2]; Hossein Ladoni [1] Background Malaria remains the most devastating vector-borne disease despite a century of ...

Presumptive treatment of fever cases as malaria: help or hindrance for malaria control?(Opinion)

Jul 16, 2008; Gosling, Roly D. ... Authors: Roly D Gosling (corresponding author) [1]; Christopher J Drakeley [1]; Alex Mwita [2]; Daniel Chandramohan [1] Background There is an increasing body of evidence suggesting that the burden of malaria in sub-Saharan Africa has been decreasing ...

Malaria in pregnant women in an area with sustained high coverage of insecticide-treated bed nets.(Research)

Jul 21, 2008; Kabanywanyi, Abdunoor M. ... Authors: Abdunoor M Kabanywanyi (corresponding author) [1,3]; John R MacArthur [2]; Wilma A Stolk [3]; J Dik F Habbema [3]; Hassan Mshinda [1]; Peter B Bloland [2]; Salim Abdulla [1]; S Patrick Kachur [1,2] Background Malaria infection during ...

Prospects, achievements, challenges and opportunities for scaling-up malaria chemoprevention in pregnancy in Tanzania: the perspective of national level officers.(Case study)

Jul 22, 2008; Mubyazi, Godfrey M. ... Authors: Godfrey M Mubyazi (corresponding author) [1,2]; Ib C Bygbjerg [3]; Pascal Magnussen [4]; Øystein Olsen [4]; Jens Byskov [4]; Kristian S Hansen [5]; Paul Bloch [4] Background The consequences of malaria effects in pregnant women are widely ...

The impact of HIV-1 o­n the malaria parasite biomass in adults in sub-Saharan Africa contributes to the emergence of antimalarial drug resistance.(Research)

Jul 22, 2008; Van geertruyden, Jean-Pierre ... Authors: Jean-Pierre Van geertruyden (corresponding author) [1]; Joris Menten [2]; Robert Colebunders [3]; Eline Korenromp [4,5]; Umberto D'Alessandro [1] Background Since the 1980s, the epidemiological overlap of HIV-1/AIDS and malaria in tropical ...

Dynamics of transmission of Plasmodium falciparum by Anopheles arabiensis and the molecular forms M and S of Anopheles gambiae in Dielmo, Senegal.(Research)

Jul 23, 2008; Ndiath, Mamadou Ousmane ... Authors: Mamadou Ousmane Ndiath (corresponding author) [1]; Cécile Brengues [2]; Lassana Konate [3]; Cheikh Sokhna [1]; Christian Boudin [1]; Jean François Trape [1]; Didier Fontenille [2] Background The Anopheles gambiae complex ...

Efficacy of local neem extracts for sustainable malaria vector control in an African village.(Research)

Jul 23, 2008; Gianotti, Rebecca L. ... Authors: Rebecca L Gianotti (corresponding author) (equal contributor) [1]; Arne Bomblies (equal contributor) [1]; Mustafa Dafalla [1]; Ibrahim Issa-Arzika [2]; Jean-Bernard Duchemin [2]; Elfatih AB Eltahir [1] Background Malaria continues to place a ...

Plasmodium falciparum variant STEVOR antigens are expressed in merozoites and possibly associated with erythrocyte invasion.(Research)

Jul 23, 2008; Khattab, Ayman ... Authors: Ayman Khattab (corresponding author) [1,3]; Insa Bonow [1]; Nadine Schreiber [1]; Michaela Petter [1]; Christel Schmetz [2]; Mo-Quen Klinkert [1] Background Of the four species causing human malaria, Plasmodium falciparum is ...

Establishment of the 1.sup.st .sup.World Health Organization International Standard for Plasmodium falciparum DNA for nucleic acid amplification technique (NAT)-based assays.(Research)

Jul 24, 2008; Padley, David J. ... Authors: David J Padley (corresponding author) [1]; Alan B Heath [1]; Colin Sutherland [2]; Peter L Chiodini [2]; Sally A Baylis [1] Background Each year there are an estimated 300 million acute cases of malaria worldwide, accounting for more than o­ne ...

Epochal changes in the association between malaria epidemics and El Nino in Sri Lanka.(Research)

Jul 24, 2008; Zubair, Lareef ... Authors: Lareef Zubair (corresponding author) [1]; Gawrie N Galappaththy [2]; Hyemin Yang [3]; Janaki Chandimala [4]; Zeenas Yahiya [4]; Priyanie Amerasinghe [5]; Neil Ward [1]; Stephen J Connor [1] Background While many factors play a role in the ...

A physiological time analysis of the duration of the gonotrophic cycle of Anopheles pseudopunctipennis and its implications for malaria transmission in Bolivia.(Research)

Jul 26, 2008; Lardeux, Frederic J. ... Authors: Frédéric J Lardeux (corresponding author) [1,2]; Rosenka H Tejerina [2]; Vicente Quispe [2]; Tamara K Chavez [2] Background In mosquito females, the blood meal is essentially used to provide energy for the maturation of eggs. Therefore, ...

Early home treatment of childhood fevers with ineffective antimalarials is deleterious in the outcome of severe malaria.(Research)

Jul 29, 2008; Orimadegun, Adebola E. ... Authors: Adebola E Orimadegun [1]; Olukemi K Amodu (corresponding author) [1]; Peter E Olumese [2]; Olayemi O Omotade Background Malaria remains a significant cause of morbidity and mortality among children and creates enormous social, economic and ...

Cohort study of the association of antibody levels to AMA1, MSP1.sub.19 , MSP3 and GLURP with protection from clinical malaria in Ghanaian children.(Research)

Jul 29, 2008; Dodoo, Daniel ... Authors: Daniel Dodoo (corresponding author) [1]; Anastasia Aikins [1]; Kwadwo Asamoah Kusi [1,2]; Helena Lamptey [1]; Ed Remarque [2]; Paul Milligan [3]; Samuel Bosomprah [4]; Roma Chilengi [5]; Yaa Difie Osei [6]; Bartholomew Dicky Akanmori [1]; Michael Theisen ...

Evaluation of the genetic polymorphism of Plasmodium falciparum P126 protein (SERA or SERP) and its influence o­n naturally acquired specific antibody responses in malaria-infected individuals living in the Brazilian Amazon.(Research)

Jul 30, 2008; Pratt-Riccio, Lilian Rose ... Authors: Lilian Rose Pratt-Riccio [1]; Selma Sallenave-Sales [1]; Joseli de Oliveira-Ferreira [1]; Bruno T da Silva [1]; Monick Lindenmeyer Guimarães [2]; Fátima Santos [3]; Thatiane S de Simone [4]; Mariza G Morgado [2]; Salvatore G de Simone [4]; Maria de Fátima ...

Utilization of insecticide-treated nets by under-five children in Nigeria: Assessing progress towards the Abuja targets.(Research)

Jul 30, 2008; Oresanya, Olusola B. ... Authors: Olusola B Oresanya (corresponding author) [1]; Moshe Hoshen [2]; Olayemi T Sofola [3] Background Malaria represents about 1.4% of the global burden of disease [1] and in Africa, it is the primary cause of disease burden as measured by ...

Malaria vector control practices in an irrigated rice agro-ecosystem in central Kenya and implications for malaria control.(Research)

Jul 31, 2008; Ng'ang'a, Peter N. ... Authors: Peter N Ng'ang'a (corresponding author) [1]; Josephat Shililu [1,2]; Gayathri Jayasinghe [3]; Violet Kimani [4]; Charity Kabutha [1]; Lucy Kabuage [5]; Ephantus Kabiru [6]; John Githure [1]; Clifford Mutero [7] Background Malaria continues to ...

A quantitative risk assessment approach for mosquito-borne diseases: malaria re-emergence in southern France.(Research)

Aug 01, 2008; Poncon, Nicolas ... Authors: Nicolas Ponçon [1]; Annelise Tran [2,3]; Céline Toty [1]; Adrian JF Luty [4]; Didier Fontenille (corresponding author) [1] Background In the past, malaria was endemic and constituted a major health issue in France in marshy areas, ...

The relationship between the haemoglobin concentration and the haematocrit in Plasmodium falciparum malaria.(Methodology)(Clinical report)

Aug 02, 2008; Lee, Sue J. ... Authors: Sue J Lee [1]; Kasia Stepniewska [1]; Nicholas Anstey [2]; Elizabeth Ashley [3]; Karen Barnes [4]; Tran Quang Binh [5]; Umberto D'Alessandro [6]; Nicholas PJ Day [1,7]; Peter J de Vries [8]; Grant Dorsey [9,10,11]; Jean-Paul Guthmann [12]; Mayfong Mayxay ...

Malaria morbidity in Papua Indonesia, an area with multidrug resistant Plasmodium vivax and Plasmodium falciparum.(Research)

Aug 02, 2008; Karyana, Muhammad ... Authors: Muhammad Karyana [1]; Lenny Burdarm [2]; Shunmay Yeung [3]; Enny Kenangalem [2,4]; Noah Wariker [4,5]; Rilia Maristela [5]; Ketut Gde Umana [5]; Ram Vemuri [6]; Maurits J Okoseray [2]; Pasi M Penttinen [5]; Peter Ebsworth [5]; Paulus Sugiarto [7]; Nicholas M ...

Consanguineous marriages and endemic malaria: can inbreeding increase population fitness?(Research)

Aug 02, 2008; Denic, Srdjan ... Authors: Srdjan Denic (corresponding author) [1]; Nicolas Nagelkerke [2,4]; Mukesh M Agarwal [3] Background Marriages between close biological relatives account for up to 60% of all marriages in many parts of Asia, Middle East and Africa [1]. A common ...

Impact of urban agriculture o­n malaria vectors in Accra, Ghana.(Research)

Aug 04, 2008; Klinkenberg, Eveline ... Authors: Eveline Klinkenberg (corresponding author) [1,2,5]; PJ McCall [2]; Michael D Wilson [3]; Felix P Amerasinghe [4]; Martin J Donnelly [2] Background There has been a resurgence of interest in the problem of urban malaria in sub-Saharan Africa ...

Ethnobotanical study of some of mosquito repellent plants in north-eastern Tanzania.(Research)

Aug 07, 2008; Kweka, Eliningaya J. ... Authors: Eliningaya J Kweka (corresponding author) [1,2]; Franklin Mosha [2]; Asanterabi Lowassa [3]; Aneth M Mahande [1,2]; Jovin Kitau [2]; Johnson Matowo [2]; Michael J Mahande [2]; Charles P Massenga [1]; Filemoni Tenu [4]; Emmanuel Feston [4]; Ester E Lyatuu [2]; ...

Gains in awareness, ownership and use of insecticide-treated nets in Nigeria, Senegal, Uganda and Zambia.(Research)

Aug 07, 2008; Baume, Carol A. ... Authors: Carol A Baume (corresponding author) [1]; M Celeste Marin [1] Background o­ne of the most effective tools for malaria prevention is the insecticide-treated mosquito net (ITN). Consistent use of ITNs can reduce malaria transmission by up to 90% ...

Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.(Methodology)(Clinical report)

Aug 09, 2008; Ashley, Elizabeth A. ... Authors: Elizabeth A Ashley (corresponding author) [1]; Loretxu Pinoges [1]; Eleanor Turyakira [1]; Grant Dorsey [2]; Francesco Checchi [3]; Hasifa Bukirwa [4]; Ingrid van den Broek [5,6]; Issaka Zongo [7]; Pedro Pablo Palma Urruta [8]; Michel van Herp [9]; Suna Balkan ...

Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1.(Research)

Aug 16, 2008; Mackintosh, Claire L. ... Authors: Claire L Mackintosh (corresponding author) [1,2,3]; Zoe Christodoulou [2]; Tabitha W Mwangi [1]; Moses Kortok [1]; Robert Pinches [2]; Thomas N Williams [1,3,4]; Kevin Marsh [1,2,3]; Christopher I Newbold [2,3] Background Maintaining ...

Phagocytosis of haemozoin (malarial pigment) enhances metalloproteinase-9 activity in human adherent monocytes: Role of IL-1beta and 15-HETE.(Research)

Aug 18, 2008; Prato, Mauro ... Authors: Mauro Prato [1]; Valentina Gallo [1]; Giuliana Giribaldi [1]; Paolo Arese (corresponding author) [1] Background Phagocytosis of haemozoin (HZ, malarial pigment) or HZ-containing trophozoites alters functionality of human monocytes and ...

Dry season ecology of Anopheles gambiae complex mosquitoes in The Gambia.(Research)

Aug 18, 2008; Jawara, Musa ... Authors: Musa Jawara [1]; Margaret Pinder [1]; Chris J Drakeley [2]; Davis C Nwakanma [1]; Ebrima Jallow [1]; Claus Bogh [3]; Steve W Lindsay [4]; David J Conway (corresponding author) [1,2] Background Malaria transmission in The Gambia occurs mainly ...

Establishment of a large semi-field system for experimental study of African malaria vector ecology and control in Tanzania.(Methodology)

Aug 20, 2008; Ferguson, Heather M. ... Authors: Heather M Ferguson (corresponding author) [1,2]; Kija R Ng'habi [2,5]; Thomas Walder [3]; Demetrius Kadungula [3]; Sarah J Moore [2,4]; Issa Lyimo [1,2]; Tanya L Russell [2,4]; Honorathy Urassa [2]; Hassan Mshinda [2]; Gerry F Killeen [2,4]; Bart GJ Knols ...

Spatial prediction of Plasmodium falciparum prevalence in Somalia.(Research)

Aug 21, 2008; Noor, Abdisalan M. ... Authors: Abdisalan M Noor (corresponding author) [1,2]; Archie CA Clements [3]; Peter W Gething [4]; Grainne Moloney [5]; Mohammed Borle [5]; Tanya Shewchuk [6]; Simon I Hay [1,7]; Robert W Snow [1,2] Background Maps of disease distribution are an ...

The M18 aspartyl aminopeptidase of Plasmodium falciparum binds to human erythrocyte spectrin in vitro.(Research)

Aug 22, 2008; Lauterbach, Sonja B. ... Authors: Sonja B Lauterbach [1]; Theresa L Coetzer (corresponding author) [1] Background Malaria, caused by an Apicomplexan of the genus Plasmodium , is o­ne of the most prevalent and lethal diseases affecting the human race. Yearly ...

Improving community health worker use of malaria rapid diagnostic tests in Zambia: package instructions, job aid and job aid-plus-training.(Research)

Aug 22, 2008; Harvey, Steven A. ... Authors: Steven A Harvey (corresponding author) [1]; Larissa Jennings [1]; Masela Chinyama [2]; Fred Masaninga [3]; Kurt Mulholland [1]; David R Bell [4] Background Widespread introduction of artemisinin combination therapy (ACT) has generated renewed ...

Malaria incidence in Limpopo Province, South Africa, 1998-2007.(Research)(Clinical report)

Aug 25, 2008; Gerritsen, Annette AM. ... Authors: Annette AM Gerritsen (corresponding author) [1]; Philip Kruger [2]; Maarten F Schim van der Loeff [3]; Martin P Grobusch [4] Background South Africa is at the southern extreme of malaria distribution in Africa. Malaria is endemic in the ...

Insertion polymorphisms of SINE200 retrotransposons within speciation islands of Anopheles gambiae molecular forms.(Research)

Aug 25, 2008; Santolamazza, Federica ... Authors: Federica Santolamazza (equal contributor) [1]; Emiliano Mancini (equal contributor) [1]; Frédéric Simard [2]; Yumin Qi [3]; Zhijian Tu [3]; Alessandra della Torre (corresponding author) [1] Background Anopheles gambiae ...

Unforeseen misuses of bed nets in fishing villages along Lake Victoria.(Research)

Aug 27, 2008; Minakawa, Noboru ... Authors: Noboru Minakawa (corresponding author) [1]; Gabriel O Dida [2]; Gorge O Sonye [3]; Kyoko Futami [1]; Satoshi Kaneko [1] Background The World Health Organization (WHO) announced the Roll Back Malaria (RBM) movement in 1998, with the goal of ...

The economic burden of malaria o­n the household in south-central Vietnam.(Research)

Aug 27, 2008; Morel, Chantal M. ... Authors: Chantal M Morel (corresponding author) [1]; Ngo Duc Thang [2]; Nguyen Xuan Xa [2]; Le Xuan Hung [2]; Le Khan Thuan [2]; Pham Van Ky [3]; Annette Erhart [4]; Anne J Mills [5]; Umberto D'Alessandro [4] Background Thousands of cases of malaria ...

Integrated vector management: The Zambian experience.(Case study)

Aug 27, 2008; Chanda, Emmanuel ... Authors: Emmanuel Chanda (corresponding author) [1]; Fred Masaninga [2]; Michael Coleman [3,8]; Chadwick Sikaala [1]; Cecilia Katebe [1]; Michael MacDonald [4]; Kumar S Baboo [5]; John Govere [6]; Lucien Manga [7] Background In 1992, the Global ...

Reduced paediatric hospitalizations for malaria and febrile illness patterns following implementation of community-based malaria control programme in rural Rwanda.(Research)(Report)

Aug 27, 2008; Sievers, Amy C. ... Authors: Amy C Sievers (corresponding author) [1,2]; Jenifer Lewey [2,3]; Placide Musafiri [2,4]; Molly F Franke [2]; Blaise J Bucyibaruta [2]; Sara N Stulac [1,2]; Michael L Rich [1,2]; Corine Karema [4]; Johanna P Daily [1] Background Combating ...

Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka.(Research)

Aug 28, 2008; Perera, M Devika B ... Authors: M Devika B Perera [1]; Janet Hemingway [2]; SHP Parakrama Karunaratne (corresponding author) [3] Background Malaria has been a major public health problem in Sri Lanka since ancient times. Several major malaria epidemics have occurred o­n the ...

Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine.(Research)

Sep 02, 2008; Sowunmi, Akintunde ... Authors: Akintunde Sowunmi (corresponding author) [1]; Sulayman T Balogun [1]; Grace O Gbotosho [1]; Christian T Happi [1] Background Amodiaquine, a Manic base related to chloroquine, is considered a safe drug for the treatment of acute, ...

Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites.(Research)(chondroitin sulfate A)

Sep 04, 2008; Fernandez, Pablo ... Authors: Pablo Fernandez [1]; Nicola KViebig [1]; Sébastien Dechavanne [2]; Catherine Lépolard [2]; Jürg Gysin [2,3]; Artur Scherf [1]; Benoit Gamain (corresponding author) [1] Background Pregnancy-associated malaria (PAM) has serious adverse outcomes ...

Dynamics of positional warfare malaria: Finland and Korea compared.(Opinion)

Sep 08, 2008; Hulden, Lena ... Authors: Lena Huldén (corresponding author) [1]; Larry Huldén [2] Background Indigenous vivax malaria was a common cause of death in the 18th and 19th century in Finland [1] ....

Efficacy, safety and tolerability of artesunate-mefloquine in the treatment of uncomplicated Plasmodium falciparum malaria in four geographic zones of Nigeria.(Research)

Sep 09, 2008; Agomo, Philip U. ... Authors: Philip U Agomo (corresponding author) [1]; Martin M Meremikwu [2]; Ismaila M Watila [3]; Innocent J Omalu [4]; Friday A Odey [2]; Stephen Oguche [4]; Valentine I Ezeiru [5]; Olugbenga O Aina [1] Background Malaria remains o­ne of the greatest ...

Antibody response dynamics to the Plasmodium falciparum conserved vaccine candidate antigen, merozoite surface protein-1 C-terminal 19kD (MSP1-19kD), in Peruvians exposed to hypoendemic malaria transmission.(Research)(Report)

Sep 09, 2008; Torres, Katherine J. ... Authors: Katherine J Torres [1]; Eva H Clark [2]; Jean N Hernandez [2]; Katherine E Soto-Cornejo [1]; Dionicia Gamboa [1]; OraLee H Branch (corresponding author) [2] Background The prospect of decreasing millions of Plasmodium falciparum ...

Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing.(Research)

Sep 11, 2008; Culleton, Richard L. ... Authors: Richard L Culleton (corresponding author) [1,12]; Toshihiro Mita [2]; Mathieu Ndounga [3]; Holger Unger [4]; Pedro VL Cravo [5]; Giacomo M Paganotti [7]; Nobuyuki Takahashi [2]; Akira Kaneko [6]; Hideaki Eto [2]; Halidou Tinto [10]; Corine Karema [11]; Umberto ...

Differences in Fcgamma receptor IIa genotypes and IgG subclass pattern of anti-malarial antibodies between sympatric ethnic groups in Mali.(Research)

Sep 15, 2008; Israelsson, Elisabeth ... Authors: Elisabeth Israelsson [1]; Manijeh Vafa [1]; Bakary Maiga [1,2]; Anna Lysén [1]; Nnaemeka C Iriemenam [1,3]; Amagana Dolo [2]; Ogobara K Doumbo [2]; Marita Troye-Blomberg [1]; Klavs Berzins (corresponding author) [1] Background Malaria remains ...

PCR-based detection of Plasmodium in Anopheles mosquitoes: a comparison of a new high-throughput assay with existing methods.(Methodology)(Clinical report)

Sep 15, 2008; Bass, Chris ... Authors: Chris Bass (corresponding author) [1]; Dimitra Nikou [2]; Andrew M Blagborough [3]; John Vontas [4]; Robert E Sinden [3]; Martin S Williamson [1]; Linda M Field [1] Background A principal component in malaria vector control and monitoring ...

Should countries implementing an artemisinin-based combination malaria treatment policy also introduce rapid diagnostic tests?(Research)(Report)

Sep 15, 2008; Zikusooka, Charlotte M. ... Authors: Charlotte M Zikusooka (corresponding author) [1]; Diane McIntyre [1]; Karen I Barnes [2] Background Malaria is a complex disease that varies in epidemiology and public health impact in different parts of the world. Estimates by the World ...

Malaria transmission in Dakar: a two-year survey.(Research)(Report)

Sep 16, 2008; Pages, Frederic ... Authors: Frederic Pagès (corresponding author) [1]; Gaetan Texier [1]; Bruno Pradines [2]; Libasse Gadiaga [3]; Vanessa Machault [1]; Fanny Jarjaval [1]; Kristell Penhoat [2]; Franck Berger [4]; Jean-François Trape [3]; Christophe Rogier [2]; Cheikh Sokhna [3] ...

Ototoxicity of artemether/lumefantrine in the treatment of falciparum malaria: a randomized trial.(Research)(Report)

Sep 16, 2008; Gurkov, Robert ... Authors: Robert Gürkov (corresponding author) [1]; Teferi Eshetu [2,3]; Isabel Barreto Miranda [3]; Nicole Berens-Riha [3]; Yoseph Mamo [4]; Tsinuel Girma [5]; Eike Krause [1]; Michael Schmidt [6]; John-Martin Hempel [1]; Thomas Löscher [3] Background ...

A community effectiveness trial of strategies promoting intermittent preventive treatment with sulphadoxine-pyrimethamine in pregnant women in rural Burkina Faso.(Research)(Report)

Sep 18, 2008; Gies, Sabine ... Authors: Sabine Gies (corresponding author) [1]; Sheick Oumar Coulibaly [2,3]; Florence Tiemegna Ouattara [4]; Clotilde Ky [3]; Bernard John Brabin [5,6]; Umberto D'Alessandro [1] Background Each year, about 50 million women living in malaria endemic ...

Malaria case-management under artemether-lumefantrine treatment policy in Uganda.(Research)(Clinical report)

Sep 19, 2008; Zurovac, Dejan ... Authors: Dejan Zurovac (corresponding author) [1,2,3]; James K Tibenderana [4,5]; Joan Nankabirwa [4]; James Ssekitooleko [6]; Julius N Njogu [1]; John B Rwakimari [7]; Sylvia Meek [8]; Ambrose Talisuna [9]; Robert W Snow [1,2] Background Forty-one ...

Transformation of the rodent malaria parasite Plasmodium chabaudi and generation of a stable fluorescent line PcGFP.sub.CON.(Methodology)(Report)

Sep 22, 2008; Reece, Sarah E. ... Authors: Sarah E Reece (corresponding author) (equal contributor) [1,2]; Joanne Thompson (corresponding author) (equal contributor) [1] Background The development of transfection technologies in Plasmodium have led to substantial ...

Anopheles gambiae complex along The Gambia river, with particular reference to the molecular forms of An. gambiae s.s.(Research)(Report)

Sep 22, 2008; Caputo, Beniamino ... Authors: Beniamino Caputo (equal contributor) [1]; Davis Nwakanma (equal contributor) [2]; Musa Jawara (equal contributor) [2]; Majidah Adiamoh [2]; Ibrahima Dia [3]; Lassana Konate [4]; Vincenzo Petrarca [5]; David J Conway (corresponding author) [2]; Alessandra della ...

Distinction of Plasmodium falciparum recrudescence and re-infection by MSP2 genotyping: a caution about unstandardized classification criteria.(Research)(Report)

Sep 23, 2008; Rouse, Petrica ... Authors: Petrica Rouse [1]; Mtawa AP Mkulama [2]; Philip E Thuma [2]; Sungano Mharakurwa (corresponding author) [1,2] Background Increasing resistance to antimalarial therapy is o­ne of the major obstacles for malaria control worldwide [1, 2, 3]. ...

MalVac: Database of malarial vaccine candidates.(Commentary)(Report)

Sep 23, 2008; Chaudhuri, Rupanjali ... Authors: Rupanjali Chaudhuri (equal contributor) [1]; Shakil Ahmed (equal contributor) [1]; Faraz Alam Ansari (equal contributor) [1]; Harinder Vir Singh [1]; Srinivasan Ramachandran (corresponding author) [1] Background Malaria is a major killer ...

Pattern of humoral immune response to Plasmodium falciparum blood stages in individuals presenting different clinical expressions of malaria.(Research)(Report)

Sep 24, 2008; Leoratti, Fabiana MS. ... Authors: Fabiana MS Leoratti [1]; Rui R Durlacher [1]; Marcus VG Lacerda [2]; Maria G Alecrim [2]; Antonio W Ferreira [1]; Maria CA Sanchez [1]; Sandra L Moraes (corresponding author) [1] Background The acquisition of natural immunity to malaria is ...

Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon.(Research)(Report)

Sep 24, 2008; Kreidenweiss, Andrea ... Authors: Andrea Kreidenweiss [1,2]; Peter G Kremsner [1,2]; Benjamin Mordmüller (corresponding author) [1,2] Background Treatment and control of Plasmodium falciparum infections in highly endemic regions strongly rely o­n chemotherapy ...

Evidence of increasing Leu-Phe knockdown resistance mutation in Anopheles gambiae from Niger following a nationwide long-lasting insecticide-treated nets implementation.(Research)(Clinical report)

Sep 25, 2008; Czeher, Cyrille ... Authors: Cyrille Czeher (corresponding author) [1]; Rabiou Labbo [1]; Ibrahim Arzika [1]; Jean-Bernard Duchemin [1] Background Plasmodium falciparum , o­ne of the deadliest pathogens circulating in Niger and many other sub-Saharan ...

Dynamics of multiple insecticide resistance in the malaria vector Anopheles gambiae in a rice growing area in South-Western Burkina Faso.(Research)(Report)

Sep 25, 2008; Dabire, Kounbobr Roch ... Authors: Kounbobr Roch Dabiré (corresponding author) [1]; Abdoulaye Diabaté [1,2]; Luc Djogbenou [3,4]; Ali Ouari [1]; Raphaël N'Guessan [4]; Jean-Bosco Ouédraogo [1]; Jean-Marc Hougard [3]; Fabrice Chandre [3]; Thierry Baldet [3,4,5] Background ...

Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: a report from three study sites in sub-Saharan Africa.(Research)(Report)

Sep 27, 2008; Ajayi, Ikeoluwapo O. ... Authors: Ikeoluwapo O Ajayi (corresponding author) [1]; Edmund N Browne [2]; Fred Bateganya [3]; Denis Yar [2]; Christian Happi [1]; Catherine O Falade [1]; Grace O Gbotosho [1]; Bidemi Yusuf [1]; Samuel Boateng [2]; Kefas Mugittu [4]; Simon Cousens [5]; Miriam Nanyunja ...

A pre-intervention study of malaria vector abundance in Rio Muni, Equatorial Guinea: Their role in malaria transmission and the incidence of insecticide resistance alleles.(Research)

Sep 29, 2008; Ridl, Frances C. ... Authors: Frances C Ridl (corresponding author) [1]; Chris Bass [2]; Miguel Torrez [3]; Dayanandan Govender [1]; Varsha Ramdeen [1]; Lee Yellot [3]; Amado Edjang Edu [4]; Christopher Schwabe [5]; Peter Mohloai [6]; Rajendra Maharaj [1]; Immo Kleinschmidt [7] ...

Insecticide resistance in Anopheles gambiae from south-western Chad, Central Africa.(Research)(Report)

Sep 29, 2008; Kerah-Hinzoumbe, Clement ... Authors: Clément Kerah-Hinzoumbé (corresponding author) [1,2,3]; Mallaye Péka [4]; Philippe Nwane [2,3]; Issa Donan-Gouni [1]; Josiane Etang [2,5]; Albert Samè-Ekobo [5]; Frédéric Simard [2,6] Background Vector control is a major component of the ...

Development of behaviour change communication strategy for a vaccination-linked malaria control tool in southern Tanzania.(Research)(Report)

Sep 29, 2008; Mushi, Adiel K. ... Authors: Adiel K Mushi [1,2]; Joanna Schellenberg (corresponding author) [2,3]; Mwifadhi Mrisho [2]; Fatuma Manzi [2]; Conrad Mbuya [2]; Haji Mponda [2]; Hassan Mshinda [2]; Marcel Tanner [4]; Pedro Alonso [5]; Robert Pool [3,5]; David Schellenberg [2,3] ...

Relation between Plasmodium falciparum asymptomatic infection and malaria attacks in a cohort of Senegalese children.(Research)(Report)

Sep 29, 2008; Le Port, Agnes ... Authors: Agnès Le Port (corresponding author) [1]; Michel Cot [1]; Jean-François Etard [2]; Oumar Gaye [3]; Florence Migot-Nabias [4]; André Garcia [4] Background Plasmodium falciparum asymptomatic carriers (ACs), i.e., ...

Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya.(Research)

Sep 30, 2008; Temperley, Matilda ... Authors: Matilda Temperley [1]; Dirk H Mueller [1]; J Kiambo Njagi [2]; Willis Akhwale [2]; Siân E Clarke [1]; Matthew CH Jukes [3]; Benson BA Estambale [4]; Simon Brooker (corresponding author) [1,5] Introduction In Africa, there is increasing ...

Dried blood spots as a source of anti-malarial antibodies for epidemiological studies.(Methodology)(Clinical report)

Sep 30, 2008; Corran, Patrick H. ... Authors: Patrick H Corran (corresponding author) [1,2]; Jackie Cook [1]; Caroline Lynch [1]; Heleen Leendertse [3]; Alphaxard Manjurano [1,3]; Jamie Griffin [4]; Jonathan Cox [1]; Tarekegn Abeku [1]; Teun Bousema [3,5]; Azra C Ghani [4]; Chris Drakeley [1,3]; Eleanor ...

Heterologous expression of plasmodial proteins for structural studies and functional annotation.(Review)

Oct 01, 2008; Birkholtz, Lyn-Marie ... Authors: Lyn-Marie Birkholtz [1]; Gregory Blatch [2]; Theresa L Coetzer [3]; Heinrich C Hoppe [1,4]; Esmaré Human [1]; Elizabeth J Morris [1,5]; Zoleka Ngcete [1]; Lyndon Oldfield [4]; Robyn Roth [4]; Addmore Shonhai [6]; Linda Stephens [2]; Abraham I Louw (corresponding ...

Therapeutic and prophylactic effect of intermittent preventive anti-malarial treatment in infants (IPTi) from Ghana and Gabon.(Research)(Clinical report)

Oct 01, 2008; May, Jurgen ... Authors: Jürgen May (corresponding author) [1,2]; Samuel Adjei [2,3]; Wibke Busch [1]; Julian J Gabor [4,5]; Saadou Issifou [4,5]; Robin Kobbe [1]; Benno Kreuels [1,6]; Bertrand Lell [4,5]; Norbert G Schwarz [4,5]; Ohene Adjei [2]; Peter G Kremsner [4,5]; Martin P ...

Impact of training in clinical and microscopy diagnosis of childhood malaria o­n antimalarial drug prescription and health outcome at primary health care level in Tanzania: A randomized controlled trial.(Research)(Clinical report)

Oct 02, 2008; Ngasala, Billy ... Authors: Billy Ngasala (corresponding author) [1,2]; Marycelina Mubi [1,2]; Marian Warsame [3,7]; Max G Petzold [3,4]; Amos Y Massele [5]; Lars L Gustafsson [6]; Goran Tomson [3]; Zul Premji [2]; Anders Bjorkman [1] Background The annual burden of ...

Predicting Global Fund grant disbursements for procurement of artemisinin-based combination therapies.(Research)(Report)

Oct 02, 2008; Cohen, Justin M. ... Authors: Justin M Cohen (corresponding author) [1]; Inder Singh [2]; Megan E O'Brien [1] Background Since the 1970s, the rise of global resistance to the cheap, ubiquitous antimalarial chloroquine (CQ) has made it imperative to find new, effective ...

Implementation of home based management of malaria in children reduces the work load for peripheral health facilities in a rural district of Burkina Faso.(Research)(Report)

Oct 03, 2008; Tiono, Alfred B. ... Authors: Alfred B Tiono [1]; Youssouf Kaboré [1]; Abdoulaye Traoré [1]; Nathalie Convelbo [1]; Franco Pagnoni [3]; Sodiomon B Sirima (corresponding author) [1,2] Background Malaria remains the leading cause of child mortality and morbidity in ...

Determinants of the accuracy of rapid diagnostic tests in malaria case management: evidence from low and moderate transmission settings in the East African highlands.(Research)(Report)

Oct 03, 2008; Abeku, Tarekegn A. ... Authors: Tarekegn A Abeku (corresponding author) [1]; Mojca Kristan [1]; Caroline Jones [1]; James Beard [1]; Dirk H Mueller [1]; Michael Okia [2]; Beth Rapuoda [3,4]; Brian Greenwood [1]; Jonathan Cox [1] Background Most countries in sub-Saharan ...

Effect of the haematocrit layer geometry o­n Plasmodium falciparum static thin-layer in vitro cultures.(Methodology)(Report)

Oct 08, 2008; Ferrer, Jordi ... Authors: Jordi Ferrer (corresponding author) (equal contributor) [1]; Marina D Rosal [2]; Jaume M Vidal (equal contributor) [2]; Clara Prats [1]; Joaquim Valls [1]; Esperanza A Herreros [2]; Daniel López [1]; Domingo Gargallo [2] Background Malaria ...

CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression.(Research)(Report)

Oct 09, 2008; Magistrado, Pamela A. ... Authors: Pamela A Magistrado (corresponding author) [1]; Trine Staalsoe [2]; Thor G Theander [1]; Lars Hviid [2]; Anja TR Jensen [1] Background Variant surface antigens (VSA) o­n the Plasmodium falciparum -infected red blood cells ...

Spatial analysis of malaria in Anhui province, China.(Research)(Report)

Oct 10, 2008; Zhang, Wenyi ... Authors: Wenyi Zhang (equal contributor) [1]; Liping Wang (equal contributor) [2]; Liqun Fang (equal contributor) [1]; Jiaqi Ma [2]; Youfu Xu [1]; Jiafu Jiang [1]; Fengming Hui [1]; Jianjun Wang [3]; Song Liang [4]; Hong Yang [1]; Wuchun Cao (corresponding author) ...

Complement factors C1q, C3 and C5 in brain and serum of mice with cerebral malaria.(Research)(Report)

Oct 10, 2008; Lackner, Peter ... Authors: Peter Lackner (corresponding author) (equal contributor) [1]; Christian Hametner (equal contributor) [1]; Ronny Beer [1]; Christoph Burger [1]; Gregor Broessner [1]; Raimund Helbok [1]; Cornelia Speth [2]; Erich Schmutzhard [1] Background ...

Spatial distribution of the chromosomal forms of anopheles gambiae in Mali.(Research)(Report)

Oct 10, 2008; Sogoba, Nafomon ... Authors: Nafomon Sogoba (corresponding author) [1,2]; Penelope Vounatsou [2]; Magaran M Bagayoko [3]; Seydou Doumbia [1]; Guimogo Dolo [1]; Laura Gosoniu [2]; Sékou F Traoré [1]; Thomas A Smith [2]; Yéya T Touré [4] Background Malaria remains o­ne of ...

Sickness behaviour pushed too far - the basis of the syndrome seen in severe protozoal, bacterial and viral diseases and post-trauma.(Review)(Report)

Oct 14, 2008; Clark, Ian A. ... Authors: Ian A Clark (corresponding author) [1]; Alison C Budd [1]; Lisa M Alleva [1] Common ground in inflammatory disease, sickness behaviour and hibernation The idea of acute infectious illness being caused by rampant overproduction of inflammatory ...

Thrombocytopaenia in pregnant women with malaria o­n the Thai-Burmese border.(Research)(Report)

Oct 15, 2008; Tan, Saw Oo ... Authors: Saw Oo Tan [1]; Rose McGready [1,2,3]; Julien Zwang [1]; Mupawjay Pimanpanarak [1]; Kanlaya Sriprawat [1]; Kyaw Lai Thwai [1]; Yoe Moo [1]; Elizabeth A Ashley [1]; Bridget Edwards [1]; Pratap Singhasivanon [2]; Nicholas J White [2,3]; François Nosten ...

Artemisinin derivatives versus quinine in treating severe malaria in children: a systematic review.(Research)(Report)

Oct 17, 2008; PrayGod, George ... Authors: George PrayGod (corresponding author) [1]; Albie de Frey [2]; Michael Eisenhut [3] Background Malaria remains a major public health problem globally. It is estimated that each year there are about 350-500 million clinical cases of malaria, ...

Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins.(Research)(Report)

Oct 20, 2008; Vignali, Marissa ... Authors: Marissa Vignali [1]; Anastasia McKinlay [1,2]; Douglas J LaCount [1,2]; Rakesh Chettier [3]; Russell Bell [3]; Sudhir Sahasrabudhe [3]; Robert E Hughes [3]; Stanley Fields (corresponding author) [1,2] Background Malaria is a devastating ...

Differences in genetic population structures of Plasmodium falciparum isolates from patients along Thai-Myanmar border with severe or uncomplicated malaria.(Research)(Report)

Oct 21, 2008; Susomboon, Pannapa ... Authors: Pannapa Susomboon [1,2]; Moritoshi Iwagami [1]; Noppadon Tangpukdee [2]; Srivicha Krusood [2]; Sornchai Looareesuwan [2]; Shigeyuki Kano (corresponding author) [1] Background Plasmodium falciparum is the most pathogenic ...

The acceptability of intermittent preventive treatment of malaria in infants (IPTi) delivered through the expanded programme of immunization in southern Tanzania.(Research)(Report)

Oct 21, 2008; Pool, Robert ... Authors: Robert Pool (corresponding author) [1,2]; Adiel Mushi [1,3,5]; Joanna Armstrong Schellenberg [1,3]; Mwifadhi Mrisho [3]; Pedro Alonso [2]; Catherine Montgomery [1]; Marcel Tanner [4]; Hassan Mshinda [3]; David Schellenberg [1,3] Background ...

Intra-specific variation of sperm length in the malaria vector Anopheles gambiae : males with shorter sperm have higher reproductive success.(Research)

Oct 21, 2008; Voordouw, Maarten J. ... Authors: Maarten J Voordouw (corresponding author) [1,2,3]; Jacob C Koella (equal contributor) [2]; Hilary Hurd (equal contributor) [3] Background Malaria kills up to three million people each year and is o­ne of the most pressing health concerns in ...

A country-wide malaria survey in Mozambique. I. Plasmodium falciparum infection in children in different epidemiological settings.(Research)(Report)

Oct 24, 2008; Mabunda, Samuel ... Authors: Samuel Mabunda (corresponding author) [1,2]; Sónia Casimiro [1,2]; Llorenç Quinto [3,4]; Pedro Alonso [3,4] Background Malaria, especially that caused by Plasmodium falciparum , remains o­ne of the most important causes of ...

Trends in malaria morbidity following the introduction of artesunate plus amodiaquine combination in M'lomp village dispensary, south-western Senegal.(Research)(Report)

Oct 24, 2008; Sarrassat, Sophie ... Authors: Sophie Sarrassat (corresponding author) [1]; Paul Senghor [2]; Jean Yves Le Hesran [1] Background Since 2001, in the face of the extension of Plasmodium falciparum resistance to commonly used antimalarials, the WHO has ...

History of malaria control in Tajikistan and rapid malaria appraisal in an agro-ecological setting.(Research)(Report)

Oct 26, 2008; Matthys, Barbara ... Authors: Barbara Matthys (corresponding author) [1]; Tohir Sherkanov [2]; Saifudin S Karimov [2]; Zamonidin Khabirov [3]; Till Mostowlansky [4]; Jürg Utzinger [5]; Kaspar Wyss [1] Background Country background The Republic of Tajikistan is a ...

Human population, urban settlement patterns and their impact o­n Plasmodium falciparum malaria endemicity.(Research)(Report)

Oct 27, 2008; Tatem, Andrew J. ... Authors: Andrew J Tatem (corresponding author) [1,2]; Carlos A Guerra [1,2]; Caroline W Kabaria [2]; Abdisalan M Noor [2,3]; Simon I Hay [1,2] Background The public health burden posed by malaria has put its control high o­n the international ...

Country-wide assessment of the genetic polymorphism in Plasmodium falciparum and Plasmodium vivax antigens detected with rapid diagnostic tests for malaria.(Research)(Report)

Oct 28, 2008; Mariette, Natacha ... Authors: Natacha Mariette (equal contributor) [1]; Céline Barnadas (equal contributor) [1]; Christiane Bouchier [2]; Magali Tichit [2]; Didier Ménard (corresponding author) [1] Background Since the emergence and spread of Plasmodium falciparum ...

Chloroquine-resistant Plasmodium vivax malaria in Debre Zeit, Ethiopia.(Research)(Report)

Oct 29, 2008; Teka, Hiwot ... Authors: Hiwot Teka (corresponding author) [1,2]; Beyene Petros [1]; Lawrence Yamuah [2]; Gezahegn Tesfaye [3]; Ibrahim Elhassan [6]; Simon Muchohi [4]; Gilbert Kokwaro [4,5]; Abraham Aseffa [2]; Howard Engers [2] Background Plasmodium ...

Operational accuracy and comparative persistent antigenicity of HRP2 rapid diagnostic tests for Plasmodium falciparum malaria in a hyperendemic region of Uganda.(Research)(Report)

Oct 29, 2008; Kyabayinze, Daniel J. ... Authors: Daniel J Kyabayinze (corresponding author) [1]; James K Tibenderana [1,2]; George W Odong [3]; John B Rwakimari [4]; Helen Counihan [5] Background Prompt and accurate diagnosis of malaria is the key to effective case management and a major ...

A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking.(Methodology)(Clinical report)

Oct 29, 2008; Daniels, Rachel ... Authors: Rachel Daniels (equal contributor) [1]; Sarah K Volkman (equal contributor) [2,3]; Danny A Milner (equal contributor) [3,4]; Nira Mahesh [2]; Daniel E Neafsey [1]; Daniel J Park [1]; David Rosen [2]; Elaine Angelino [5]; Pardis C Sabeti [1]; Dyann F Wirth [2]; ...

A highly sensitive, PCR-based method for the detection of Plasmodium falciparum clones in microtiter plates.(Methodology)(polymerase chain reaction)(Report)

Oct 29, 2008; Maher, Steven P. ... Authors: Steven P Maher (equal contributor) [1]; Bharath Balu (equal contributor) [1]; Doug A Shoue [2]; Matthew E Weissenbach [1]; John H Adams (corresponding author) [1] Background Isolating clones of Plasmodium falciparum is a ...

Social and cultural aspects of 'malaria' and its control in central Cote d'Ivoire.(Research)

Oct 30, 2008; Esse, Clemence ... Authors: Clémence Essé [1,2]; Jürg Utzinger [3]; Andres B Tschannen [2]; Giovanna Raso [4,5]; Constanze Pfeiffer [3]; Stefanie Granado [3]; Benjamin G Koudou [2,6]; Eliézer K N'Goran [2,6]; Guéladio Cissé [2]; Olivier Girardin [7]; Marcel Tanner [3]; Brigit Obrist ...

The effect of a single blood meal o­n the phenotypic expression of insecticide resistance in the major malaria vector Anopheles funestus.(Research)(Report)

Oct 31, 2008; Spillings, Belinda L. ... Authors: Belinda L Spillings [1,2]; Maureen Coetzee [1,2,3]; Lizette L Koekemoer [1,2]; Basil D Brooke (corresponding author) [1,2] Background Malaria is the most prevalent vector borne disease worldwide, and predominantly affects third world and ...

Spatio-seasonal modeling of the incidence rate of malaria in Mozambique.(Research)(Clinical report)

Oct 31, 2008; Abellana, Rosa ... Authors: Rosa Abellana (corresponding author) [1]; Carlos Ascaso [1,2]; John Aponte [2,3]; Francisco Saute [3]; Delino Nhalungo [3]; Ariel Nhacolo [3]; Pedro Alonso [2,3] Background Malaria has been and still is the cause of much human morbidity and ...

Willingness and ability to pay for artemisinin-based combination therapy in rural Tanzania.(Research)(Report)

Oct 31, 2008; Saulo, Eleonor C. ... Authors: Eleonor C Saulo [1]; Birger C Forsberg (corresponding author) [2]; Zul Premji [3]; Scott M Montgomery [4]; Anders Björkman [1] Background Malaria constitutes a major burden o­n individuals and o­n the community in low-income countries. In ...

Assessment of the pharmacokinetics and dynamics of two combination regimens of fosmidomycin-clindamycin in patients with acute uncomplicated falciparum malaria.(Research)(Clinical report)

Oct 31, 2008; Ruangweerayut, Ronnatrai ... Authors: Ronnatrai Ruangweerayut [1]; Sornchai Looareesuwan [2]; David Hutchinson [3]; Anurak Chauemung [4]; Vick Banmairuroi [4]; Kesara Na-Bangchang (corresponding author) [4] Background The increasing devastation of malarial infections is currently ...

Spread of anti-malarial drug resistance: mathematical model with implications for ACT drug policies.(artemisinin-based combination therapy)(Research)(Clinical report)

Nov 02, 2008; Pongtavornpinyo, Wirichada ... Authors: Wirichada Pongtavornpinyo (corresponding author) [1]; Shunmay Yeung [1,2,4]; Ian M Hastings [3]; Arjen M Dondorp [1,4]; Nicholas PJ Day [1,4]; Nicholas J White [1,4] Background For the past half-century, the malaria parasites of humans have ...

Evaluation of two counterflow traps for testing behaviour-mediating compounds for the malaria vector Anopheles gambiae s.s. under semi-field conditions in Tanzania.(Research)(Report)

Nov 03, 2008; Schmied, Wolfgang H. ... Authors: Wolfgang H Schmied [1,2]; Willem Takken [3]; Gerry F Killeen [2,4]; Bart GJ Knols [3]; Renate C Smallegange (corresponding author) [3] Background Due to the role of mosquitoes in disease transmission and their impact o­n human well-being ...

Variations in entomological indices in relation to weather patterns and malaria incidence in East African highlands: implications for epidemic prevention and control.(Research)(Report)

Nov 04, 2008; Kristan, Mojca ... Authors: Mojca Kristan (corresponding author) [1]; Tarekegn A Abeku [1]; James Beard [1]; Michael Okia [2]; Beth Rapuoda [3]; James Sang [3]; Jonathan Cox [1] Background The highlands of East Africa are characterized by unstable malaria transmission ...

Overuse of artemisinin-combination therapy in Mto wa Mbu ( river of mosquitoes ), an area misinterpreted as high endemic for malaria.(Research)(Clinical report)

Nov 05, 2008; Mwanziva, Charles ... Authors: Charles Mwanziva [1,2]; Seif Shekalaghe [1,3]; Arnold Ndaro [2]; Bianca Mengerink [1]; Simon Megiroo [4]; Frank Mosha [3]; Robert Sauerwein [1]; Chris Drakeley [5,6]; Roly Gosling [6]; Teun Bousema (corresponding author) [1] Background ...

Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate o­n the north-western border of Thailand.(Research)(Clinical report)

Nov 06, 2008; Carrara, Verena I. ... Authors: Verena I Carrara (equal contributor) [1]; Aung P Phyo (equal contributor) [1]; Paw Nwee [1]; Ma Soe [1]; Hsar Htoo [1]; Jaruwan Arunkamomkiri [1]; Pratap Singhasivanon [2]; François Nosten (corresponding author) [1,2,3] Background Artemisinin ...

Implementation of intermittent preventive treatment in pregnancy with sulphadoxine/pyrimethamine (IPTp-SP) at a district health centre in rural Senegal.(Research)(Clinical report)

Nov 07, 2008; Olliaro, Piero L. ... Authors: Piero L Olliaro (corresponding author) [1]; Henriette Delenne [2]; Moustafa Cisse [3]; Malick Badiane [3]; Alberto Olliaro [4]; Michel Vaillant [5]; Philippe Brasseur [6] Background Acquiring malaria during pregnancy contributes to maternal ...

Declining incidence of malaria imported into the UK from West Africa.(Research)

Nov 10, 2008; Behrens, Ron H. ... Authors: Ron H Behrens (corresponding author) [1,3]; Bernadette Carroll [1]; Valerie Smith [2]; Neal Alexander [3] Background Malaria remains a threat to travellers visiting endemic regions. Since 1987, approximately 39,000 cases of malaria have been ...

Prevalence of pfmdr1 , pfcrt , pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola.(Research)(Clinical report)

Nov 17, 2008; Figueiredo, Paula ... Authors: Paula Figueiredo (corresponding author) [1]; Carla Benchimol [2]; Dinora Lopes [1]; Luís Bernardino [2]; Virgílio E do Rosário [1]; Luís Varandas [3]; Fátima Nogueira [1] Background Malaria is endemic throughout much of the Angolan territory, ...

A randomized trial to monitor the efficacy and effectiveness by QT-NASBA of artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment and transmission control of uncomplicated Plasmodium falciparum malaria in western Kenya.(Research)(Quantitative nucleic sequence based amplification)(Clinical report)

Nov 18, 2008; Mens, Petra F. ... Authors: Petra F Mens (corresponding author) [1,2]; Patrick Sawa [3]; Sandra M van Amsterdam [1]; Inge Versteeg [1]; Sabah A Omar [4]; Henk DFH Schallig [1]; Piet A Kager [2] Background In response to widespread resistance of Plasmodium ...

Alterations o­n peripheral B cell subsets following an acute uncomplicated clinical malaria infection in children.(Research)(Clinical report)

Nov 18, 2008; Asito, Amolo S. ... Authors: Amolo S Asito [1,2]; Ann M Moormann [3]; Chelimo Kiprotich [2]; Zipporah W Ng'ang'a [1]; Robert Ploutz-Snyder [4,6]; Rosemary Rochford (corresponding author) [5] Background There are over 500 million episodes of clinical Plasmodium ...

Dispensary level pilot implementation of rapid diagnostic tests: an evaluation of RDT acceptance and usage by providers and patients - Tanzania, 2005.(Research)(rapid diagnostic tests)(Report)

Nov 19, 2008; Williams, Holly Ann ... Authors: Holly Ann Williams (corresponding author) [1]; Louise Causer [2]; Emmy Metta [3]; Aggrey Malila [3]; Terrence O'Reilly [4]; Salim Abdulla [2]; S Patrick Kachur [4]; Peter B Bloland [4] Background Clinical diagnosis of malaria is sensitive but ...

Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil.(Research)(Report)

Nov 20, 2008; Sutherland, Colin J. ... Authors: Colin J Sutherland (corresponding author) [1,2]; Matt Laundy [1]; Nicholas Price [3]; Martina Burke [2]; Quinton L Fivelman [2]; Geoffrey Pasvol [4]; John L Klein [3]; Peter L Chiodini [1,2] Background The hydroxynaphthoquinone compound ...

Extensive dynamics of Plasmodium falciparum densities, stages and genotyping profiles.(Research)(Clinical report)

Nov 21, 2008; Farnert, Anna ... Authors: Anna Färnert (corresponding author) [1]; Marianne Lebbad [2]; Lea Faraja [3]; Ingegerd Rooth [3] Background Longitudinal studies with repeated genotyping of Plasmodium falciparum infections in partially immune individuals in ...

Sublingual sugar for hypoglycaemia in children with severe malaria: A pilot clinical study.(Research)(Clinical report)

Nov 23, 2008; Graz, Bertrand ... Authors: Bertrand Graz [1,2]; Moussa Dicko [3,4]; Merlin L Willcox [1,5]; Bernard Lambert [6]; Jacques Falquet [1]; Mathieu Forster [7]; Sergio Giani [8]; Chiaka Diakite [3]; Eugène M Dembele [4]; Drissa Diallo [3]; Hubert Barennes (corresponding author) [9,10] ...

Experimental conditions affect the outcome of Plasmodium falciparum platelet-mediated clumping assays.(Research)

Nov 24, 2008; Arman, Monica ... Authors: Mònica Arman [1]; J Alexandra Rowe (corresponding author) [1] Background Plasmodium parasites causing malaria are responsible for 300-500 million infections annually. Among the four species that infect humans, ...

The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence.(Review)(Clinical report)

Nov 25, 2008; Premji, Zulfiqarali G. ... Authors: Zulfiqarali G Premji (corresponding author) [1]; Salim Abdulla [2]; Bernhards Ogutu [3]; Alice Ndong [4]; Catherine O Falade [5]; Issaka Sagara [6]; Nathan Mulure [7]; Obiyo Nwaiwu [8]; Gilbert Kokwaro [9,10] Background Progress in the o­ntrol ...

Malaria treatment-seeking behaviour and recovery from malaria in a highland area of Kenya.(Research)

Nov 26, 2008; Sumba, Peter O. ... Authors: Peter O Sumba [1]; S Lindsey Wong [2]; Hemal K Kanzaria [3]; Kelsey A Johnson [4]; Chandy C John (corresponding author) [4] Background Malaria is a leading cause of death in children under the age of five years in sub-Saharan Africa [1]. The ...

Evaluation of the efficacy and safety of artemether-lumefantrine in the treatment of acute uncomplicated Plasmodium falciparum malaria in Nigerian infants and children.(Research)(Report)

Nov 27, 2008; Falade, Catherine O. ... Authors: Catherine O Falade (corresponding author) [1,2]; Oluwatoyin O Ogunkunle [3]; Hannah O Dada-Adegbola [4]; Adegoke G Falade [3]; Patricia Ibarra de Palacios [5]; Philip Hunt [6]; Mailis Virtanen [5]; Ayoade M Oduola [2]; Lateef A Salako [1] ...

Pyrethroid resistance in the major malaria vector Anopheles arabiensis from Gwave, a malaria-endemic area in Zimbabwe.(Research)(Report)

Nov 28, 2008; Munhenga, Givemore ... Authors: Givemore Munhenga [1,2,3]; Hieronymo T Masendu [4]; Basil D Brooke [2,5]; Richard H Hunt [2,3]; Lizette K Koekemoer (corresponding author) [2,5] Background Malaria remains the most important parasitic disease in Zimbabwe causing significant ...

Evaluation and optimization of membrane feeding compared to direct feeding as an assay for infectivity.(Methodology)(Report)

Dec 02, 2008; Diallo, Mouctar ... Authors: Mouctar Diallo (corresponding author) [1]; Abdoulaye M Touré [1,6]; Sekou F Traoré [1]; Oumou Niaré [1]; Lalla Kassambara [1]; Awa Konaré [2]; Mamadou Coulibaly [1]; Magaran Bagayogo [3]; John C Beier [4,7]; Richard K Sakai [1]; Yéya T Touré [5]; Ogobara K ...

Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity.(Research)(Report)

Dec 03, 2008; Stepniewska, Kasia ... Authors: Kasia Stepniewska (corresponding author) [1,2]; Ric N Price [2,3]; Colin J Sutherland [4]; Chris J Drakeley [4]; Lorenz von Seidlein [1,4,5]; Francois Nosten [1,2,6]; Nicholas J White [1,2] Background Malaria control rests traditionally o­n ...

Variations in host genes encoding adhesion molecules and susceptibility to falciparum malaria in India.(Research)(Clinical report)

Dec 04, 2008; Sinha, Swapnil ... Authors: Swapnil Sinha [1]; Tabish Qidwai [1]; Kanika Kanchan [1]; Prerna Anand [2]; Ganga N Jha [1]; Sudhanshu S Pati [3]; Sanjib Mohanty [3]; Saroj K Mishra [3]; Prajesh K Tyagi [4]; Surya K Sharma [4]; [5]; Vimala Venkatesh [2]; Saman Habib (corresponding author) ...

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.(Research)(neutrophil cytosolic factor 1)(Report)

Dec 11, 2008; Greve, Bernhard ... Authors: Bernhard Greve (corresponding author) (equal contributor) [1]; Peter Hoffmann (equal contributor) [1]; Reinhard Vonthein [2]; Jürgen Kun [3]; Bertrand Lell [3,4]; Marcin P Mycko [5]; Krysztof W Selmaj [5]; Klaus Berger [6]; Robert Weissert [1,7]; Peter G ...

A Plasmodium yoelii soluble factor inhibits the phenotypic maturation of dendritic cells.(Research)(Clinical report)

Dec 15, 2008; Orengo, Jamie M. ... Authors: Jamie M Orengo [1,2]; Kurt A Wong [1]; Carlos Ocaña-Morgner [1,3]; Ana Rodriguez (corresponding author) [1] Background The interactions of the Plasmodium parasite with the immune system of the host are complex in many ...

Falciparum malaria and HIV-1 in hospitalized adults in Maputo, Mozambique: does HIV-infection obscure the malaria diagnosis?(Research)(Clinical report)

Dec 15, 2008; Berg, Aase ... Authors: Aase Berg (corresponding author) [1,2]; Sam Patel [2]; Nina Langeland [3]; Bjorn Blomberg [3] Background The number of studies o­n prevalence and clinical manifestations of HIV 1 and falciparum malaria in Mozambique is limited, especially in ...

Opposed circulating plasma levels of endothelin-1 and C-type natriuretic peptide in children with Plasmodium falciparum malaria.(Research)(Clinical report)

Dec 15, 2008; Dietmann, Anelia ... Authors: Anelia Dietmann (corresponding author) [1,3]; Peter Lackner [1]; Raimund Helbok [1,3]; Katharina Spora [1,3]; Saadou Issifou [3]; Bertrand Lell [3]; Markus Reindl [1]; Peter G Kremsner [2,3]; Erich Schmutzhard [1] Background Malaria, beside ...

Survival and haematological recovery of children with severe malaria transfused in accordance to WHO guidelines in Kilifi, Kenya.(Research)

Dec 16, 2008; Akech, Samuel O. ... Authors: Samuel O Akech (corresponding author) [1]; Oliver Hassall [1,2]; Allan Pamba [1]; Richard Idro [1,3]; Thomas N Williams [1,4]; Charles RJC Newton [1,5,6]; Kathryn Maitland [1,7] Background Annually approximately two billion people are exposed ...

Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy.(Review)(Report)

Dec 16, 2008; Chico, R Matthew ... Authors: R Matthew Chico (corresponding author) [1]; Rudiger Pittrof [2]; Brian Greenwood [1]; Daniel Chandramohan [1] Background Each year, 30 million pregnancies are at risk of malaria infection in sub-Saharan Africa, representing a major public ...

Does the drug sensitivity of malaria parasites depend o­n their virulence?(Research)(Report)

Dec 16, 2008; Schneider, Petra ... Authors: Petra Schneider (corresponding author) [1,2]; Brian HK Chan [1,3]; Sarah E Reece [1,2]; Andrew F Read [1,3] Background Patients in endemic areas often carry malaria parasites while having levels of antimalarial drugs in their blood that fail ...

Costs and consequences of large-scale vector control for malaria.(Research)(Report)

Dec 17, 2008; Yukich, Joshua O. ... Authors: Joshua O Yukich [1]; Christian Lengeler (corresponding author) [1]; Fabrizio Tediosi [1,2]; Nick Brown [1,3]; Jo-Ann Mulligan [4]; Des Chavasse [5]; Warren Stevens [6]; John Justino [7]; Lesong Conteh [1,4]; Rajendra Maharaj [8]; Marcy Erskine [9]; Dirk H ...

Individual, facility and policy level influences o­n national coverage estimates for intermittent preventive treatment of malaria in pregnancy in Tanzania.(Research)(Clinical report)

Dec 18, 2008; Marchant, Tanya ... Authors: Tanya Marchant (corresponding author) [1]; Rose Nathan [3]; Caroline Jones [2]; Hadji Mponda [3]; Jane Bruce [2]; Yovitha Sedekia [3]; Joanna Schellenberg [2]; Hassan Mshinda [3]; Kara Hanson [1] Background Over the last decade a number of ...

Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodium falciparum malaria.(Research)(Report)

Dec 18, 2008; Taylor, Walter RJ. ... Authors: Walter RJ Taylor (corresponding author) [1,2]; Hendra Widjaja [1]; Hasan Basri [1]; Colin Ohrt [3]; Taufik [4]; Emiliana Tjitra [5]; Samuel Baso [6]; David Fryauff [1]; Stephen L Hoffman [7]; Thomas L Richie [1] Background The malaria induced ...

A randomized trial o­n effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children.(Research)(Clinical report)

Dec 19, 2008; Kobbe, Robin ... Authors: Robin Kobbe (corresponding author) [1,6]; Philipp Klein [1]; Samuel Adjei [2,3]; Solomon Amemasor [4]; William Nana Thompson [4]; Hanna Heidemann [1]; Maja V Nielsen [1]; Julia Vohwinkel [1]; Benedikt Hogan [1]; Benno Kreuels [1,7]; Martina Bührlen [4]; Wibke ...

A randomized, open-label, comparative efficacy trial of artemether-lumefantrine suspension versus artemether-lumefantrine tablets for treatment of uncomplicated Plasmodium falciparum malaria in children in western Kenya.(Research)(Report)

Dec 22, 2008; Juma, Elizabeth A. ... Authors: Elizabeth A Juma (corresponding author) [1]; Charles O Obonyo [1]; Willis S Akhwale [2]; Bernhards R Ogutu [3] Background Resistance to the commonly used anti-malarial drugs has probably contributed substantially to the increased morbidity ...

Improving the cost-effectiveness of IRS with climate informed health surveillance systems.(Research)(indoor residual spraying)(Report)

Dec 24, 2008; Worrall, Eve ... Authors: Eve Worrall (corresponding author) [1]; Stephen J Connor [2]; Madeleine C Thomson [2] Background Quantifying the burden of malaria remains a major challenge as many infections may be asymptomatic, inadequate diagnosis and reporting and the ...

Malaria Journal back issues from January 2009

Identification and bioinformatic characterization of a multidrug resistance associated protein (ABCC) gene in Plasmodium berghei.(Research)(Clinical report)

Jan 02, 2009; Gonzalez-Pons, Maria ... Authors: María González-Pons (equal contributor) [1]; Ada C Szeto (equal contributor) [1,3]; Ricardo González-Méndez [2]; Adelfa E Serrano (corresponding author) [1] Background The ATP-binding cassette (ABC) superfamily is o­ne of the largest ...

Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy.(Research)(Report)

Jan 05, 2009; Dodoo, Alexander NO. ... Authors: Alexander NO Dodoo (corresponding author) [1]; Carole Fogg [2,3]; Alex Asiimwe [3]; Edmund T Nartey [1]; Augustina Kodua [1]; Ofori Tenkorang [1]; David Ofori-Adjei [1] Background Artemisinin combination therapy (ACT) is becoming first-line ...

Rapid decrease of malaria morbidity following the introduction of community-based monitoring in a rural area of central Vietnam.(Research)(Report)

Jan 05, 2009; Thang, Ngo Duc ... Authors: Ngo Duc Thang (corresponding author) [1]; Annette Erhart [2]; Le Xuan Hung [1]; Le Khanh Thuan [1]; Nguyen Xuan Xa [1]; Nguyen Ngoc Thanh [1]; Pham Van Ky [3]; Marc Coosemans [2]; Nico Speybroeck [2,4]; Umberto D'Alessandro [2] Background In ...

Age patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensity.(Review)(Clinical report)

Jan 07, 2009; Okiro, Emelda A. ... Authors: Emelda A Okiro (corresponding author) [1]; Abdullah Al-Taiar [2]; Hugh Reyburn [3,4]; Richard Idro [5,6]; James A Berkley [6,7]; Robert W Snow [1,7] Background During the 1980's and 1990's a series of epidemiological observations were ...

Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali.(Research)(Report)

Jan 07, 2009; Kayentao, Kassoum ... Authors: Kassoum Kayentao (corresponding author) [1]; Hamma Maiga [1]; Robert D Newman [2]; Meredith L McMorrow [2]; Annett Hoppe [2]; Oumar Yattara [1]; Hamidou Traore [1]; Younoussou Kone [1]; Etienne A Guirou [1]; Renion Saye [1]; Boubacar Traore [1]; Abdoulaye Djimde ...

Seasonal prevalence of malaria in West Sumba district, Indonesia.(Research)(Clinical report)

Jan 09, 2009; Syafruddin, Din ... Authors: Din Syafruddin [1]; Krisin [2]; Puji Asih [1]; Sekartuti [3]; Rita M Dewi [3]; Farah Coutrier [1]; Ismail E Rozy [1]; Augustina I Susanti [2]; Iqbal RF Elyazar [2]; Awalludin Sutamihardja [2]; Agus Rahmat [2]; Michael Kinzer [2]; William O Rogers (corresponding ...

Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women.(Research)(Report)

Jan 09, 2009; Mayor, Alfredo ... Authors: Alfredo Mayor (corresponding author) [1,2]; Elisa Serra-Casas [1,2]; Azucena Bardají [1,2]; Sergi Sanz [1]; Laura Puyol [1]; Pau Cisteró [1]; Betuel Sigauque [2,3]; Inacio Mandomando [1,2,3]; John J Aponte [1,2]; Pedro L Alonso [1,2]; Clara Menéndez [1,2] ...

Complement consumption in children with Plasmodium falciparum malaria.(Research)(Report)

Jan 09, 2009; Nyakoe, Nancy K. ... Authors: Nancy K Nyakoe [1]; Ronald P Taylor [2]; Joseph N Makumi [3]; John N Waitumbi (corresponding author) [1] Background There is ample evidence to indicate that malaria antigens, either o­n infected erythrocytes (iE), or as free antigens released ...

Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia.(Research)(Clinical report)

Jan 12, 2009; Lim, Pharath ... Authors: Pharath Lim (corresponding author) [1]; Alisa P Alker [2]; Nimol Khim [1]; Naman K Shah [2]; Sandra Incardona [1]; Socheat Doung [3]; Poravuth Yi [3]; Denis Mey Bouth [4]; Christiane Bouchier [5]; Odile Mercereau Puijalon [6]; Steven R Meshnick [2]; Chansuda ...

Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia.(Research)(Clinical report)

Jan 12, 2009; Rogers, William O. ... Authors: William O Rogers (corresponding author) [1]; Rithy Sem [2,3]; Thong Tero [4]; Pheaktra Chim [3]; Pharath Lim [3]; Sinuon Muth [2]; Duong Socheat [2]; Frédéric Ariey [3]; Chansuda Wongsrichanalai [1,5] Background The spread of drug resistant ...

Prevalence of Plasmodium spp. in malaria asymptomatic African migrants assessed by nucleic acid sequence based amplification.(Research)(Report)

Jan 12, 2009; Marangi, Marianna ... Authors: Marianna Marangi [1]; Rocco Di Tullio [2]; Pètra F Mens [3]; Domenico Martinelli [4]; Vincenzina Fazio [5]; Gioacchino Angarano [2]; Henk DFH Schallig [3]; Annunziata Giangaspero [1]; Gaetano Scotto (corresponding author) [2] Background ...

Social and environmental malaria risk factors in urban areas of Ouagadougou, Burkina Faso.(Research)(Report)

Jan 13, 2009; Baragatti, Meili ... Authors: Meili Baragatti [1]; Florence Fournet [2]; Marie-Claire Henry [3]; Serge Assi [4,1]; Herman Ouedraogo [5]; Christophe Rogier (corresponding author) [1]; Gérard Salem [6] Background According to the UN Population Fund's State of World ...

Initial evidence of reduction of malaria cases and deaths in Rwanda and Ethiopia due to rapid scale-up of malaria prevention and treatment.(Research)(Report)

Jan 14, 2009; Otten, Mac ... Authors: Mac Otten (corresponding author) [1]; Maru Aregawi [1]; Wilson Were [1]; Corine Karema [2]; Ambachew Medin [1]; Worku Bekele [3]; Daddi Jima [4]; Khoti Gausi [5]; Ryuichi Komatsu [6]; Eline Korenromp [6]; Daniel Low-Beer [6]; Mark Grabowsky [6] ...

Swedish traveller with Plasmodium knowlesi malaria after visiting Malaysian Borneo.(Case report)(Clinical report)

Jan 16, 2009; Bronner, Ulf ... Authors: Ulf Bronner [1]; Paul CS Divis [2]; Anna Färnert [1]; Balbir Singh (corresponding author) [2] Background Plasmodium knowlesi occurs in nature in long-tailed and pig-tailed macaques (Macaca fascicularis ...

Sickle cell trait (HbAS) and stunting in children below two years of age in an area of high malaria transmission.(Research)(Report)

Jan 16, 2009; Kreuels, Benno ... Authors: Benno Kreuels (corresponding author) [1,2,3]; Stephan Ehrhardt [3]; Christina Kreuzberg [1]; Samuel Adjei [4]; Robin Kobbe [5]; Gerd D Burchard [1,3]; Christa Ehmen [6]; Matilda Ayim [7]; Ohene Adjei [7]; Jürgen May [2] Background There is ...

Costs of early detection systems for epidemic malaria in highland areas of Kenya and Uganda.(Research)(Report)

Jan 16, 2009; Mueller, Dirk H. ... Authors: Dirk H Mueller (corresponding author) [1]; Tarekegn A Abeku [2]; Michael Okia [3]; Beth Rapuoda [4]; Jonathan Cox [2] Background Despite continuing research o­n the epidemiology and control of malaria epidemics, little is known about the ...

Malaria transmission in two localities in north-western Argentina.(Research)(Report)

Jan 19, 2009; Dantur Juri, Maria J. ... Authors: María J Dantur Juri (corresponding author) [1]; Mario Zaidenberg [2]; Guillermo L Claps [1]; Mirta Santana [3]; Walter R Almirón [4] Background Malaria, o­ne of the most important human parasitic diseases, seemed to be under control in the ...

The multiplicity of malaria transmission: a review of entomological inoculation rate measurements and methods across sub-Saharan Africa.(Review)(Report)

Jan 23, 2009; Kelly-Hope, Louise A. ... Authors: Louise A Kelly-Hope (corresponding author) [1,2]; F Ellis McKenzie [2] Background Malaria is the most common, serious mosquito-borne disease in the world [1], yet the tools and methods used to measure the intensity of its transmission are ...

Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East.(Research)(Report)

Jan 28, 2009; Zakeri, Sedigheh ... Authors: Sedigheh Zakeri (corresponding author) [1]; Shadi Rabiei Motmaen [1,2]; Mandana Afsharpad [1]; Navid Dinparast Djadid [1] Background Plasmodium vivax remains the most widespread malaria parasite in areas outside of ...

Malaria and water resource development: the case of Gilgel-Gibe hydroelectric dam in Ethiopia.(Research)(Report)

Jan 29, 2009; Yewhalaw, Delenasaw ... Authors: Delenasaw Yewhalaw [1]; Worku Legesse [2]; Wim Van Bortel [3]; Solomon Gebre-Selassie [4]; Helmut Kloos [5]; Luc Duchateau [6]; Niko Speybroeck (corresponding author) [7,8] Background Malaria is o­ne of the most important causes of morbidity ...

Malaria Journal 2009

Clinical trials to estimate the efficacy of preventive interventions against malaria in paediatric populations: a methodological review.(Review)(Report)

Feb 10, 2009; Moorthy, Vasee S. ... Authors: Vasee S Moorthy (corresponding author) [1,2]; Zarifah Reed [2]; Peter G Smith [3] Background The development and deployment of new and improved intervention methods for malaria control shows promising signs of reducing significantly the ...

Quality of anti-malarial drugs provided by public and private healthcare providers in south-east Nigeria.(Research)

Feb 10, 2009; o­nwujekwe, Obinna ... Authors: Obinna o­nwujekwe (corresponding author) [1,2]; Harparkash Kaur [3]; Nkem Dike [2,4]; Elvis Shu [2]; Benjamin Uzochukwu [2,5]; Kara Hanson [3]; Viola Okoye [6]; Paul Okonkwo [2] Background People seek treatment for malaria from public sector ...

Estimating the burden of malaria in pregnancy: a case study from rural Madhya Pradesh, India.(Research)(Clinical report)

Feb 12, 2009; Diamond-Smith, Nadia ... Authors: Nadia Diamond-Smith (corresponding author) [1]; Neeru Singh [2]; RK Das Gupta [3]; Aditya Dash [4]; Krongthong Thimasarn [5]; Oona MR Campbell [1]; Daniel Chandramohan [1] Background In high malaria-transmission settings such as much of ...

Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin.(Research)(Report)

Feb 12, 2009; Mishra, Kirti ... Authors: Kirti Mishra [1]; Aditya P Dash [2]; Bijay K Swain [3]; Nrisingha Dey (corresponding author) [1] Background The effective anti-malarial activity of the two plant-based drugs, quinine and artemisinin, has generated much interest to explore ...

Micro-geographic risk factors for malarial infection.(Research)(Report)

Feb 13, 2009; Myers, Ward P. ... Authors: Ward P Myers (corresponding author) [1,2]; Andrea P Myers [2]; Janet Cox-Singh [3]; Hui C Lau [3]; Benny Mokuai [4]; Richard Malley [1] Background Knowledge of geography is integral to the study of disease within populations. This is ...

Community knowledge, attitudes and practices (KAP) o­n malaria in Swaziland: A country earmarked for malaria elimination.(Research)(Report)

Feb 19, 2009; Hlongwana, Khumbulani W. ... Authors: Khumbulani W Hlongwana (corresponding author) [1]; Musawenkosi LH Mabaso [1]; Simon Kunene [2]; Dayanandan Govender [1]; Rajendra Maharaj [1] Background Malaria remains a major cause of morbidity and mortality in tropical and subtropical ...

Household possession, use and non-use of treated or untreated mosquito nets in two ecologically diverse regions of Nigeria - Niger Delta and Sahel Savannah.(Research)(Report)

Feb 19, 2009; Afolabi, Bamgboye M. ... Authors: Bamgboye M Afolabi (corresponding author) [1]; Olayemi T Sofola [2]; Bayo S Fatunmbi [3]; William Komakech [3]; Festus Okoh [2]; Oladele Saliu [4]; Peju Otsemobor [2]; Olusola B Oresanya [2]; Chioma N Amajoh [2]; David Fasiku [5]; Inuwa Jalingo [5] ...

Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in Niger.(Research)(Polymerase chain reactions/re)(restriction fragment length polymorphism )(Report)

Feb 23, 2009; Ibrahim, Maman Laminou ... Authors: Maman Laminou Ibrahim (corresponding author) [1]; Nicolas Steenkeste [2]; Nimol Khim [2]; Hadiza Hassane Adam [1]; Lassana Konaté [3]; Jean-Yves Coppée [4]; Fredéric Ariey [2]; Jean-Bernard Duchemin [1] Background Malaria drug resistance is a ...

Physical and chemical stability of expired fixed dose combination artemether-lumefantrine in uncontrolled tropical conditions.(Research)

Feb 25, 2009; Bate, Roger ... Authors: Roger Bate (corresponding author) [1,2]; Richard Tren [1]; Kimberly Hess [1]; Amir Attaran [3] Background Improving access to effective anti-malarial treatment is a priority of most donors, United Nations agencies and national governments. In ...

Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali.(Research)(Report)

Feb 26, 2009; Tekete, Mamadou ... Authors: Mamadou Tekete [1]; Abdoulaye A Djimde (corresponding author) [1]; Abdoul H Beavogui [1]; Hamma Maiga [1]; Issaka Sagara [1]; Bakary Fofana [1]; Dinkorma Ouologuem [1]; Souleymane Dama [1]; Aminatou Kone [1]; Demba Dembele [1]; Mamadou Wele [1]; Alassane Dicko ...

Glatiramer acetate reduces the risk for experimental cerebral malaria: a pilot study.(Research)(Report)

Feb 27, 2009; Lackner, Peter ... Authors: Peter Lackner (corresponding author) [1]; Andrea Part [1]; Christoph Burger [1]; Anelia Dietmann [1]; Gregor Broessner [1]; Raimund Helbok [1]; Markus Reindl [1]; Erich Schmutzhard [1]; Ronny Beer [1] Background A major cause of morbidity and ...

Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria o­n the Benin coast, West Africa.(Research)(Report)

Mar 03, 2009; Nahum, Alain ... Authors: Alain Nahum (corresponding author) [1]; Annette Erhart [2]; Daniel Ahounou [1]; Désiré Bonou [1]; Chantal Van Overmeir [2]; Joris Menten [2]; Martin Akogbeto [1]; Marc Coosemans [2]; Achille Massougbodji [3]; Umberto D'Alessandro [2] Background ...

Utilization of public or private health care providers by febrile children after user fee removal in Uganda.(Research)

Mar 14, 2009; Rutebemberwa, Elizeus ... Authors: Elizeus Rutebemberwa (corresponding author) [1,2]; George Pariyo [1]; Stefan Peterson [1,2,3]; Goran Tomson [2]; Karin Kallander [2,4] Background Infant and child mortality rates due to febrile illnesses are high in resource poor countries, ...

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