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Phần 5: Nghiên cứu về tổn thương não màng não do loài amip ăn não người Naeglaria fowleri vẫn còn bỏ ngõ và tỷ lệ tử vong còn cao

Việc nghiên cứu và tìm hiểu về một tác nhân gây bệnh, đặc biệt là các tác nhân ký sinh trùng nhiệt đới bị lãng quên là rất quan trọng bởi nếu bỏ qua, chúng dễ dàng dẫn đến các biến chứng nguy hiểm và đe dọa tính mạng của bệnh nhân và cả cộng đồng nếu nguy cơ lây nhiễm cao.

Một trong những tác nhân ký sinh trùng đơn bào gây bệnh nghiêm trọng cơ quan thần kinh trung ương ở người với tỷ lệ tử vong lên đến gần 100% mặc dù bệnh nhân đang ở trong các cơ sở y tế hiện đại và ở quốc gia có nền y học bậc nhất thế giới. Đó chính là loại amip ăn não Naegleria fowleri đã gây tử vong 2 bệnh nhân ở Việt Nam năm 2014.

Delta-9-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, exacerbates brain infection by Acanthamoeba.

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Serology of Naegleria fowleri and Naegleria lovaniensis in a hospital survey.

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Thermal ecology of Naegleria fowleri from a power plant cooling reservoir.

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Primary amoebic meningoencephalitis with subsequent organ procurement: a case study.

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J Neurosci Nurs. 2011 Oct;43(5):274-9. doi: 10.1097/JNN.0b013e318227ef6e.

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Photo Quiz. Primary amebic meningoencephalitis.

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Clin Infect Dis. 2012 Dec;55(12):1677, 1737-8. doi: 10.1093/cid/cis668. No abstract available.

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[Studies o­n the cell-mediated immunity in experimental Naegleria spp. infections].

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Naegleria fowleri in chick embryos. Effects of embryo age and incubation temperature, and the infectivity of embryo-derived amebae for mice.

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Amebic meningoencephalitides and keratitis: challenges in diagnosis and treatment.

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Survey for the presence of Naegleria fowleri amebae in lake water used to cool reactors at a nuclear power generating plant.

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Parasitol Res. 2009 Apr;104(5):969-78. doi: 10.1007/s00436-008-1275-y. Epub 2008 Nov 29.

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A case report: primary amoebic meningoencephalitis in a young Zambian adult.

Chomba M, Mucheleng'anga LA, Fwoloshi S, Ngulube J, Mutengo MM.

BMC Infect Dis. 2017 Aug 1;17(1):532. doi: 10.1186/s12879-017-2638-8.

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Identification and Molecular Typing of Naegleria fowleri from a Patient of Primary Amebic Meningoencephalitis (PAM) in China.

Zhang LL, Wu M, Hu BC, Chen HL, Pan JR, Ruan W, Yao LN.

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Naegleria Fowleri--the brain-eating amoeba.

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Population Structure in Naegleria fowleri as Revealed by Microsatellite Markers.

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[Primary amebic meningoencephalitis caused by Naegleria fowleri in an adolescent from Huetamo, Michoacan, Mexico].

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Molecular confirmation of Sappinia pedata as a causative agent of amoebic encephalitis.

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Curative properties of muramyl dipeptide in experimental Naegleria meningoencephalitis.

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Paravahlkampfia francinae n. sp. masquerading as an agent of primary amoebic meningoencephalitis.

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Primary amebic meningoencephalitis associated with ritual nasal rinsing—St Thomas, US Virgin Islands, 2012.

[No authors listed]

Clin Infect Dis. 2014 Feb;58(3):ii. No abstract available.

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Comparison of the clinical presentations of Naegleria fowleri primary amoebic meningoencephalitis with pneumococcal meningitis: a case-control study.

Zahid MF, Saad Shaukat MH, Ahmed B, Beg MA, Kadir MM, Mahmood SF.

Infection. 2016 Aug;44(4):505-11. doi: 10.1007/s15010-016-0878-y. Epub 2016 Feb 27.

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Neutrophils extracellular traps damage Naegleria fowleri trophozoites opsonized with human IgG.

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Iron-Binding Protein Degradation by Cysteine Proteases of Naegleria fowleri.

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Kidney and liver transplants from a donor infected with Naegleria fowleri.

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Pathogenic Naegleria fowleri and non-pathogenic Naegleria lovaniensis exhibit differential adhesion to, and invasion of, extracellular matrix proteins.

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Microbiology. 2012 Mar;158(Pt 3):791-803. doi: 10.1099/mic.0.055020-0. Epub 2012 Jan 5.

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Amebic meningoencephalitis: spectrum of imaging findings.

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Primary amoebic meningoencephalitis in North Queensland: the paediatric experience.

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Med J Aust. 2016 Oct 3;205(7):325-8. Review.

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Movement of Naegleria fowleri stimulated by mammalian cells in vitro.

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J Protozool. 1986 Feb;33(1):10-3.

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Naegleria fowleri lysate induces strong cytopathic effects and pro-inflammatory cytokine release in rat microglial cells.

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Korean J Parasitol. 2011 Sep;49(3):285-90. doi: 10.3347/kjp.2011.49.3.285. Epub 2011 Sep 30.

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Effect of thermal additions o­n the density and distribution of thermophilic amoebae and pathogenic Naegleria fowleri in a newly created cooling lake.

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Characterization of a Drinking Water Distribution Pipeline Terminally Colonized by Naegleria fowleri.

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Environ Sci Technol. 2016 Mar 15;50(6):2890-8. doi: 10.1021/acs.est.5b05657. Epub 2016 Feb 24.

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Evaluation of the indirect fluorescent-antibody technique for identification of Naegleria species.

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Genotyping Naegleria spp. and Naegleria fowleri isolates by interrepeat polymerase chain reaction.

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Primary amoebic meningo-encephalitis due to Naegleria fowleri.

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J Indian Med Assoc. 2011 Jul;109(7):500-1.

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The production and characterization of anti-Naegleria fowleri monoclonal antibodies.

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[Resistance to Naegleria fowleri infection passively acquired from immunized splenocyte, serum or milk].

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Kisaengchunghak Chapchi. 1989 Jun;27(2):79-86. Korean.

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A case of primary amoebic meningoencephalitis: North Island, New Zealand.

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N Z Med J. 2003 Dec 12;116(1187):U712. No abstract available.

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Case Series of Naegleria fowleri Primary Ameobic Meningoencephalitis from Karachi, Pakistan.

Ghanchi NK, Jamil B, Khan E, Ansar Z, Samreen A, Zafar A, Hasan Z.

Am J Trop Med Hyg. 2017 Nov;97(5):1600-1602. doi: 10.4269/ajtmh.17-0110. Epub 2017 Oct 10.

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Detection and significance of the potentially pathogenic amoeboflagellate Naegleria italica in Australia.

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Ultrastructural studies o­n the effect of tumor necrosis factor o­n the interaction of neutrophils and Naegleria fowleri.

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Clinical case of cerebral amebiasis caused by E. histolytica.

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Primary amoebic meningoencephalitis--rare and lethal.

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N Z Med J. 2003 Dec 12;116(1187):U705. No abstract available.

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Primary Amebic Meningoencephalitis Associated with Hot Spring Exposure During International Travel - Seminole County, Florida, July 2014.

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MMWR Morb Mortal Wkly Rep. 2015 Nov 6;64(43):1226. doi: 10.15585/mmwr.mm6443a5. No abstract available.

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[Will Naegleria fowleri become a public health problem?].

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Naegleria fowleri Meningoencephalitis Associated with Public Water Supply, Pakistan, 2014.

Ghanchi NK, Khan E, Khan A, Muhammad W, Malik FR, Zafar A.

Emerg Infect Dis. 2016 Oct;22(10):1835-7. doi: 10.3201/eid2210.151236. No abstract available.

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PCR detection and analysis of the free-living amoeba Naegleria in hot springs in Yellowstone and Grand Teton National Parks.

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A brief survey of free-living amebae in Thailand and Hamamatsu District, Japan.

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Primary amoebic meningoencephalitis: amoebicidal effects of clinically approved drugs against Naegleria fowleri.

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Prompt diagnosis and extraordinary survival from Naegleria fowleri meningitis: a rare case report.

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Comparison of Naegleria fowleri and Naegleria gruberi cultivated in the same nutrient medium.

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Notes from the field: primary amebic meningoencephalitis associated with ritual nasal rinsing--St. Thomas, U.S. Virgin islands, 2012.

Centers for Disease Control and Prevention (CDC).

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Another killer of the Australian bush: a rapidly fatal meningoencephalitis in a child.

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[Infections caused by free-living amebas. Historical commentaries, taxonomy and nomenclature, protozoology and clinicopathologic features].

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Cell surface differences of Naegleria fowleri and Naegleria lovaniensis exposed with surface markers.

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Immunodominant antigens in Naegleria fowleri excretory--secretory proteins were potential pathogenic factors.

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Modulation of biological functions of Naegleria fowleri amoebae by growth medium.

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Dependence of growth, metabolic expression, and pathogenicity of Naegleria fowleri o­n exogenous porphyrins.

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Naegleria fowleri after 50 years: is it a neglected pathogen?

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J Med Microbiol. 2016 Sep;65(9):885-896. doi: 10.1099/jmm.0.000303. Epub 2016 Jul 4.

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Two new strains of Naegleria fowleri isolated from a case of primary amoebic meningoencephalitis.

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Virulence of Naegleria fowleri affected by axenic cultivation and passage in mice.

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Primary amebic meningoencephalitis in Florida: a case report and epidemiological review of Florida cases.

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Successful treatment of Naegleria fowleri meningoencephalitis by using intravenous amphotericin B, fluconazole and rifampicin.

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Comparison of real-time PCR methods for the detection of Naegleria fowleri in surface water and sediment.

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[Natural killer cell activity in Naegleria fowleri infected mice].

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Depression of immunity to Naegleria fowleri in mice by selective depletion of neutrophils with a monoclonal antibody.

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Seasonal distribution of pathogenic free-living amebae in Oklahoma waters.

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Proteinases in Naegleria Fowleri (strain NF3), a pathogenic amoeba: a preliminary study.

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Cytopathogenicity of Naegleria fowleri and Naegleria gruberi for established mammalian cell cultures.

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[Immunization effect o­n Naegleria fowleri infection in splenectomized mice]

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Five cases of primary amebic meningoencephalitis in Mexicali, Mexico: study of the isolates.

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Immunohistochemical characterization of the initial stages of Naegleria fowleri meningoencephalitis in mice.

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The distribution of Naegleria fowleri in man-made thermal waters.

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Concentration of Naegleria fowleri in natural waters used for recreational purposes in Sonora, Mexico (November 2007-October 2008).

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Exp Parasitol. 2010 Sep;126(1):33-6. doi: 10.1016/j.exppara.2010.04.011. Epub 2010 Apr 22.

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Indian Pediatr. 1998 Oct;35(10):1012-5. No abstract available.

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Differentiation of Naegleria fowleri from other species of Naegleria using monoclonal antibodies and the polymerase chain reaction.

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[Human diseases caused by free-living amoebae. II. Primary amebic ++ meningoencephalitis].

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[Amebic granulomatosis encephalitis due to Balamuthia mandrillaris: fatal disease increasingly recognized in Latin America].

Seas R C, Bravo P F.

Rev Chilena Infectol. 2006 Sep;23(3):197-9. Epub 2006 Aug 4. Spanish. No abstract available.

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Primary amoebic meningo-encephalitis in southern Africa.

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J Infect. 1993 Mar;26(2):211-4.

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The occurrence of Naegleria fowleri in recreational waters in Arizona.

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J Environ Sci Health A Tox Hazard Subst Environ Eng. 2014 Sep 19;49(11):1322-30. doi: 10.1080/10934529.2014.910342.

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[Interleukin-2 production and alteration of T cell subsets in mice infected with Naegleria fowleri].

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Primary Amebic Meningoencephalitis in Children: A Report of Two Fatal Cases and Review of the Literature.

Stowe RC, Pehlivan D, Friederich KE, Lopez MA, DiCarlo SM, Boerwinkle VL.

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Decreasing effect of an anti-Nfa1 polyclonal antibody o­n the in vitro cytotoxicity of pathogenic Naegleria fowleri.

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[The protective effects of monoclonal antibodies in mice from Naegleria fowleri infection].

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Notes from the Field: Primary Amebic Meningoencephalitis Associated with Exposure to Swimming Pool Water Supplied by an Overland Pipe - Inyo County, California, 2015.

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Comparison of biofilm ecology supporting growth of individual Naegleria species in a drinking water distribution system.

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In vitro antiproliferative effects of neuroleptics, antimycotics and antibiotics o­n the human pathogens Acanthamoeba polyphaga and Naegleria fowleri.

Ondarza RN, Iturbe A, Hernández E.

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A method for assessing the migratory response of Naegleria fowleri utilizing [3H]uridine-labeled amoebae.

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Occurrence of Naegleria species in therapeutic geothermal water sources, Northern Iran.

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Scanning electron microscopic study of human neuroblastoma cells affected with Naegleria fowleri Thai strains.

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Biocidal efficacy of monochloramine against planktonic and biofilm-associated Naegleria fowleri cells.

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In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri.

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Improved Method for the Detection and Quantification of Naegleria fowleri in Water and Sediment Using Immunomagnetic Separation and Real-Time PCR.

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Rare brain infection avoided with safe sinus irrigation.

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Ancient weapons for attack and defense: the pore-forming polypeptides of pathogenic enteric and free-living amoeboid protozoa.

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Brain-Eating Amoebae: Silver Nanoparticle Conjugation Enhanced Efficacy of Anti-Amoebic Drugs against Naegleria fowleri.

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Soil is the origin for the presence of Naegleria fowleri in the thermal recreational waters.

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Experimental Naegleria fowleri meningoencephalitis in sheep: light and electron microscopic studies.

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Production of Nfa1-specific monoclonal antibodies that influences the in vitro cytotoxicity of Naegleria fowleri trophozoites o­n microglial cells.

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Cerva L.

Folia Parasitol (Praha). 1980;27(1):1-9.

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Novel in vitro and in vivo models to study central nervous system infections due to Acanthamoeba spp.

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Primary amoebic meningoencephalitis: fifteen years later.

Thong YH.

Med J Aust. 1980 Apr 19;1(8):352-4. Review.

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Primary Amebic Meningoencephalitis as Cause of Headache and Fever.

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Am Fam Physician. 2016 Apr 15;93(8):644. No abstract available.

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Immunization with live amoebae, amoebic lysate and culture supernatant in experimental Naegleria meningoencephalitis.

Thong YH, Ferrante A, Rowan-Kelly B, O'Keefe D.

Trans R Soc Trop Med Hyg. 1980;74(5):570-6.

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Heat shock protein 70 of Naegleria fowleri is important factor for proliferation and in vitro cytotoxicity.

Song KJ, Song KH, Kim JH, Sohn HJ, Lee YJ, Park CE, Shin HJ.

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Isolation of Naegleria fowleri from pond water in West Bengal, India.

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Naegleria fowleri: nfa1 gene knock-down by double-stranded RNAs.

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[First isolation in Italy of Naegleria australiensis (De Jonckheere, 1981)].

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Youngest survivor of naegleria meningitis.

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[Granulomatous amebic encephalitis caused by Balamuthia mandrillaris. First case diagnosed in Chile].

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ANTI-AMEBIC ACTIVITY OF DIOSGENIN o­n NAEGLERIA FOWLERI TROPHOZOITES.

Rabablert J, Tiewcharoen S, Auewarakul P, Atithep T, Lumlerdkij N, Vejaratpimol R, Junnu V.

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Free-living amoebae isolated in the Central African Republic: epidemiological and molecular aspects.

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Acanthamoeba culbertsoni and Naegleria fowleri: occurrence of antibodies in man.

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Animal model of human disease. Primary amebic meningoencephalitis, Naegleria meningoencephalitis, CNS protozoal infection.

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Primary amebic meningoencephalitis in a patient with AIDS: unusual protozoological findings.

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Acanthamebic meningoencephalitis presenting as personality change.

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[No authors listed]

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[Occurrence of Naegleria fowleri in a free environment and biological properties of isolated strains].

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Effects of cyclophosphamide and a metabolite, acrolein, o­n Naegleria fowleri in vitro and in vivo.

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Ngày 29/06/2018
TS.BS. Huỳnh Hồng Quang  

THÔNG BÁO

   Dịch vụ khám chữa bệnh chuyên khoa của Viện Sốt rét-KST-CT Quy Nhơn về các bệnh ký sinh trùng và các bệnh do véc tơ truyền, đặc biệt là các bệnh ký sinh trùng mới nổi như sán lá gan lớn, sán lá gan nhỏ, giun lươn, giun đũa chó và các bệnh thông thường khác; khám và xét nghiệm chẩn đoán bệnh bằng các phương tiện kỹ thuật cao như sinh hóa, huyết học, miễn dịch (ELISA), sinh học phân tử và chẩn đoán hình ảnh bằng nội soi tiêu hóa, siêu âm màu…

   Trung tâm Dịch vụ khoa học kỹ thuật của Viện Sốt rét-Ký sinh trùng-Côn trùng Quy Nhơn thuộc Bộ Y tế chuyên sản xuất mua bán hóa chất, vật tư, chế phẩm diệt côn trùng; dịch vụ diệt côn trùng gây bệnh, côn trùng gia dụng như muỗi, ruồi, gián, kiến…; dịch vụ phòng diệt mối mọt và xét nghiệm phát hiện tôm bằng các kỹ thuật hiện đại.


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Trang tin điện tử Viện Sốt rét - Ký Sinh trùng - Côn trùng Quy Nhơn
Giấy phép thiết lập số 53/GP - BC do Bộ văn hóa thông tin cấp ngày 24/4/2005
Địa chỉ: Khu vực 8-Phường Nhơn Phú-Thành phố Quy Nhơn- Tỉnh Bình Định.
Tel: (84) 0256.3547492 - Fax: (84) 0256.3647464
Email: impe.quynhon@gmail.com
Trưởng ban biên tập: TTND.PGS.TS. Nguyễn Văn Chương - Viện trưởng
Phó Trưởng ban biên tập: TS.BS.Huỳnh Hồng Quang-Phó Viện trưởng
• Thiết kế bởi công ty cổ phần phần mềm: Quảng Ích