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Các ấn phẩm phân tích gen học về bệnh nhiễm trùng do Viện Nghiên cứu di truyền Sanger Institute đăng tải (Phần 4_Các ấn bản năm 2014)

·Genomic confirmation of hybridisation and recent inbreeding in a vector - isolated Leishmania population.

Rogers MB, Downing T, Smith BA, Imamura H, Sanders M, Svobodova M, Volf P, Berriman M, Cotton JA and Smith DF

PLoS genetics 2014;10;1;e1004092

·Vitamin B₁₂-dependent taurine synthesis regulates growth and bone mass.

Roman-Garcia P, Quiros-Gonzalez I, Mottram L, Lieben L, Sharan K, Wangwiwatsin A, Tubio J, Lewis K, Wilkinson D, Santhanam B, Sarper N, Clare S, Vassiliou GS, Velagapudi VR, Dougan G and Yadav VK

The Journal of clinical investigation 2014;124;7;2988-3002

·A comparison of key aspects of gene regulation in Streptomyces coelicolor and Escherichia coli using nucleotide-resolution transcription maps produced in parallel by global and differential RNA sequencing.

Romero DA, Hasan AH, Lin YF, Kime L, Ruiz-Larrabeiti O, Urem M, Bucca G, Mamanova L, Laing EE, van Wezel GP, Smith CP, Kaberdin VR and McDowall KJ

Molecular microbiology 2014

·Allele-specific regulation of DISC1 expression by miR-135b-5p.

Rossi M, Kilpinen H, Muona M, Surakka I, Ingle C, Lahtinen J, Hennah W, Ripatti S and Hovatta I

European journal of human genetics : EJHG 2014;22;6;840-3

·Genetic background drives transcriptional variation in human induced pluripotent stem cells.

Rouhani F, Kumasaka N, de Brito MC, Bradley A, Vallier L and Gaffney D

PLoS genetics 2014;10;6;e1004432

·Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase.

Ryder E, Doe B, Gleeson D, Houghton R, Dalvi P, Grau E, Habib B, Miklejewska E, Newman S, Sethi D, Sinclair C, Vyas S, Wardle-Jones H et al.,

Transgenic research 2014;23;1;177-85

·Deconstructing pheromone-mediated behavior o­ne layer at a time.

Sánchez-Andrade G and Logan DW

BMC biology 2014;12;1;33

·Redundant mechanisms to form silent chromatin at pericentromeric regions rely o­n BEND3 and DNA methylation.

Saksouk N, Barth TK, Ziegler-Birling C, Olova N, Nowak A, Rey E, Mateos-Langerak J, Urbach S, Reik W, Torres-Padilla ME, Imhof A, Déjardin J and Simboeck E

Molecular cell 2014;56;4;580-94

·Sequence of a Complete Chicken BG Haplotype Shows Dynamic Expansion and Contraction of Two Gene Lineages with Particular Expression Patterns.

Salomonsen J, Chattaway JA, Chan AC, Parker A, Huguet S, Marston DA, Rogers SL, Wu Z, Smith AL, Staines K, Butter C, Riegert P, Vainio O et al.,

PLoS genetics 2014;10;6;e1004417

·Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia.

Salsbury G, Cambridge EL, McIntyre Z, Arends MJ, Karp NA, Isherwood C, Shannon C, Hooks Y, Sanger Mouse Genetics Project, Ramirez-Solis R, Adams DJ, White JK and Speak AO

Experimental hematology 2014;42;12;1053-8.e1

·The food-borne identity.

Salter SJ

Nature reviews. Microbiology 2014

·Reagent and laboratory contamination can critically impact sequence-based microbiome analyses.

Salter SJ, Cox MJ, Turek EM, Calus ST, Cookson WO, Moffatt MF, Turner P, Parkhill J, Loman NJ and Walker AW

BMC biology 2014;12;87

·A framework for the interpretation of de novo mutation in human disease.

Samocha KE, Robinson EB, Sanders SJ, Stevens C, Sabo A, McGrath LM, Kosmicki JA, Rehnström K, Mallick S, Kirby A, Wall DP et al.,

Nature genetics 2014

·Potential of human induced pluripotent stem cells in studies of liver disease.

Sampaziotis F, Segeritz CP and Vallier L

Hepatology (Baltimore, Md.) 2014

·Population and single cell genomics reveal the Aire-dependency, relief from Polycomb silencing and distribution of self-antigen expression in thymic epithelia.

Sansom SN, Shikama N, Zhanybekova S, Nusspaumer G, Macaulay IC, Deadman ME, Heger A, Ponting CP and Holländer GA

Genome research 2014

·Impact of infectious diseases consultation o­n the management of Staphylococcus aureus bacteraemia in children.

Saunderson RB, Gouliouris T, Cartwright EJ, Nickerson EJ, Aliyu SH, O'Donnell DR, Kelsall W, Limmathurotsakul D, Peacock SJ and Török ME

BMJ open 2014;4;7;e004659

·The Yersinia pseudotuberculosis complex: characterization and delineation of a new species, Yersinia wautersii.

Savin C, Martin L, Bouchier C, Filali S, Chenau J, Zhou Z, Becher F, Fukushima H, Thomson NR, Scholz HC and Carniel E

International journal of medical microbiology : IJMM 2014;304;3-4;452-63

·A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.

Schönhuber N, Seidler B, Schuck K, Veltkamp C, Schachtler C, Zukowska M, Eser S, Feyerabend TB, Paul MC, Eser P, Klein S, Lowy AM et al.,

Nature medicine 2014

·Inferring human population size and separation history from multiple genome sequences.

Schiffels S and Durbin R

Nature genetics 2014;46;8;919-25

·TreeFam v9: a new website, more species and orthology-on-the-fly.

Schreiber F, Patricio M, Muffato M, Pignatelli M and Bateman A

Nucleic acids research 2014;42;1;D922-5

·Single Cell Genomics meeting in Stockholm: from single cells to cell types.

Scialdone A, Achim K and Marioni JC

Genome biology 2014;15;10;496

·Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity.

Scott RA, Fall T, Pasko D, Barker A, Sharp SJ, Arriola L, Balkau B, Barricarte A, Barroso I, Boeing H, Clavel-Chapelon F, Crowe FL, Dekker JM et al.,

Diabetes 2014

·Whole-exome sequencing of patients with severe disorders of insulin action

Semple,R. and BARROSO,I.

Frontiers in Diabetes 2014;23;87-101

·Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci.

Service SK, Teslovich TM, Fuchsberger C, Ramensky V, Yajnik P, Koboldt DC, Larson DE, Zhang Q, Lin L, Welch R, Ding L, McLellan MD, O'Laughlin M et al.,

PLoS genetics 2014;10;1;e1004147

·Genomic epidemiology of Vibrio cholerae O1 associated with floods, Pakistan, 2010.

Shah MA, Mutreja A, Thomson N, Baker S, Parkhill J, Dougan G, Bokhari H and Wren BW

Emerging infectious diseases 2014;20;1;13-20

·Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya.

Shah SS, Macharia A, Makale J, Uyoga S, Kivinen K, Craik R, Hubbart C, Wellems TE, Rockett KA, Kwiatkowski DP and Williams TN

BMC medical genetics 2014;15;1;93

·Hypothalamic control of bone metabolism.

Sharan K and Yadav VK

Best practice & research. Clinical endocrinology & metabolism 2014;28;5;713-23

·Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

Shen B, Zhang W, Zhang J, Zhou J, Wang J, Chen L, Wang L, Hodgkins A, Iyer V, Huang X and Skarnes WC

Nature methods 2014;11;4;399-402

·Cryptic ecology among host generalist Campylobacter jejuni in domestic animals.

Sheppard SK, Cheng L, Méric G, de Haan CP, Llarena AK, Marttinen P, Vidal A, Ridley A, Clifton-Hadley F, Connor TR, Strachan NJ, Forbes K et al,

Molecular ecology 2014;23;10;2442-51

·Structural genomics analysis of uncharacterized protein families overrepresented in human gut bacteria identifies a novel glycoside hydrolase.

Sheydina A, Eberhardt RY, Rigden DJ, Chang Y, Li Z, Zmasek CC, Axelrod HL and Godzik A

BMC bioinformatics 2014;15;1;112

·An atlas of genetic influences o­n human blood metabolites.

Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L et al.,

Nature genetics 2014;46;6;543-50

·Plasmid deficiency in urogenital isolates of Chlamydia trachomatis reduces infectivity and virulence in a mouse model.

Sigar IM, Schripsema JH, Wang Y, Clarke IN, Cutcliffe LT, Seth-Smith HM, Thomson NR, Bjartling C, Unemo M, Persson K and Ramsey KH

Pathogens and disease 2014;70;1;61-9

·Dissecting mammalian immunity through mutation.

Siggs OM

Immunology and cell biology 2014

·Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.

Siggs OM, Grieve A, Xu H, Bambrough P, Christova Y and Freeman M

Biology open 2014

·European surveillance network for influenza in pigs: surveillance programs, diagnostic tools and Swine influenza virus subtypes identified in 14 European countries from 2010 to 2013.

Simon G, Larsen LE, Dürrwald R, Foni E, Harder T, Van Reeth K, Markowska-Daniel I, Reid SM, Dan A, Maldonado J, Huovilainen A, Billinis C, Davidson I et al.,

PloS o­ne 2014;9;12;e115815

·A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.

Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R, Kafsack BF, Williams AE et al.,

Nature 2014;507;7491;253-7

·Comparative analysis of pseudogenes across three phyla.

Sisu C, Pei B, Leng J, Frankish A, Zhang Y, Balasubramanian S, Harte R, Wang D, Rutenberg-Schoenberg M, Clark W, Diekhans M, Rozowsky J, Hubbard T, Harrow J and Gerstein MB

Proceedings of the National Academy of Sciences of the United States of America 2014;111;37;13361-6

·Luminal Microbes Promote Monocyte-Stem Cell Interactions Across a Healthy Colonic Epithelium.

Skoczek DA, Walczysko P, Horn N, Parris A, Clare S, Williams MR and Sobolewski A

Journal of immunology (Baltimore, Md. : 1950) 2014

·Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity.

Smallwood SA, Lee HJ, Angermueller C, Krueger F, Saadeh H, Peat J, Andrews SR, Stegle O, Reik W and Kelsey G

Nature methods 2014;11;8;817-20

·Walking the interactome for candidate prioritization in exome sequencing studies of Mendelian diseases.

Smedley D, Köhler S, Czeschik JC, Amberger J, Bocchini C, Hamosh A, Veldboer J, Zemojtel T and Robinson PN

Bioinformatics (Oxford, England) 2014;30;22;3215-22

·Use of animal models for exome prioritization of rare disease genes.

Smedley D, Kohler S, Bone W, Oellrich A, Jacobsen J, Sanger Mouse Genetics Project, Wang K, Mungall C, Washington N, Bauer S, Seelow D, Krawitz P et al.,

Orphanet journal of rare diseases 2014;9;1;836

·IFITM proteins-cellular inhibitors of viral entry.

Smith S, Weston S, Kellam P and Marsh M

Current opinion in virology 2014;4;71-7

·DrsG from Streptococcus dysgalactiae subsp. equisimilis Inhibits the Antimicrobial Peptide LL-37.

Smyth D, Cameron A, Davies MR, McNeilly C, Hafner L, Sriprakash KS and McMillan DJ

Infection and immunity 2014;82;6;2337-44

·Investigating the Feasibility of Scale up and Automation of Human Induced Pluripotent Stem Cells Cultured in Aggregates in Feeder Free Conditions.

Soares F, Chandra A, Thomas R, Pedersen R, Vallier L and Williams D

Journal of biotechnology 2014

·International Coordination of Large-Scale Human Induced Pluripotent Stem Cell Initiatives: Wellcome Trust and ISSCR Workshops White Paper.

Soares FA, Sheldon M, Rao M, Mummery C and Vallier L

Stem cell reports 2014;3;6;931-9

·Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis.

Sotillo J, Sanchez-Flores A, Cantacessi C, Harcus Y, Pickering D, Bouchery T, Camberis M, Tang SC, Giacomin P, Mulvenna J, Mitreva M, Berriman M, LeGros G, Maizels RM and Loukas A

Molecular & cellular proteomics : MCP 2014;13;10;2736-51

·A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.

Speed D, Hoggart C, Petrovski S, Tachmazidou I, Coffey A, Jorgensen A, Eleftherohorinou H, De Iorio M, Todaro M, De T, Smith D, Smith PE et al.,

Human molecular genetics 2014;23;1;247-58

·Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.

Stacey MA, Marsden M, Pham N TA, Clare S, Dolton G, Stack G, Jones E, Klenerman P, Gallimore AM, Taylor PR, Snelgrove RJ, Lawley TD et al.,

Cell host & microbe 2014;15;4;471-83

·Development of an antigen microarray for high throughput monoclonal antibody selection.

Staudt N, Müller-Sienerth N and Wright GJ

Biochemical and biophysical research communications 2014;445;4;785-90

·Common variant at 16p11.2 conferring risk of psychosis.

Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E et al.,

Molecular psychiatry 2014;19;1;108-14

·Comparative genome analysis of Wolbachia strain wAu.

Sutton ER, Harris SR, Parkhill J and Sinkins SP

BMC genomics 2014;15;928

·Zero tolerance for healthcare-associated MRSA bacteraemia: is it realistic?

Török ME, Harris SR, Cartwright EJ, Raven KE, Brown NM, Allison ME, Greaves D, Quail MA, Limmathurotsakul D, Holden MT, Parkhill J and Peacock SJ

The Journal of antimicrobial chemotherapy 2014;69;8;2238-45

·Resetting transcription factor control circuitry toward ground-state pluripotency in human.

Takashima Y, Guo G, Loos R, Nichols J, Ficz G, Krueger F, Oxley D, Santos F, Clarke J, Mansfield W, Reik W, Bertone P and Smith A

Cell 2014;158;6;1254-69

·Random projection based clustering for population genomics

Tasoulis,S, Cheng,L, Valimaki,N, Croucher,N.J, HARRIS,S.R, Hanage,W.P, Roos,T and Corander,J

Proceedings - 2014 IEEE International Conference o­n Big Data, IEEE Big Data 2014 2014;675-82

·Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium.

Taylor AE, Fluharty ME, Bjørngaard JH, Gabrielsen ME, Skorpen F, Marioni RE, Campbell A, Engmann J, Mirza SS, Loukola A, Laatikainen T, Partonen T et al.,

BMJ open 2014;4;10;e006141

·Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers.

Taylor AE, Morris RW, Fluharty ME, Bjorngaard JH, Asvold BO, Gabrielsen ME, Campbell A, Marioni R, Kumari M, Hällfors J, Männistö S, Marques-Vidal P et al.,

PLoS genetics 2014;10;12;e1004799

·Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population.

Tekola-Ayele F, Adeyemo A, Aseffa A, Hailu E, Finan C, Davey G, Rotimi CN and Newport MJ

The pharmacogenomics journal 2014

·Differential PfEMP1 expression is associated with cerebral malaria pathology.

Tembo DL, Nyoni B, Murikoli RV, Mukaka M, Milner DA, Berriman M, Rogerson SJ, Taylor TE, Molyneux ME, Mandala WL, Craig AG and Montgomery J

PLoS pathogens 2014;10;12;e1004537

·Loss-of-function mutations in APOC3, triglycerides, and coronary disease.

TG and HDL Working Group of the Exome Sequencing Project, National Heart, Lung, and Blood Institute, Crosby J, Peloso GM, Auer PL, Crosslin DR, Stitziel NO et al.,

The New England journal of medicine 2014;371;1;22-31

·Inactivating Mutations in NPC1L1 and Protection from Coronary Heart Disease.

The Myocardial Infarction Genetics Consortium Investigators

The New England journal of medicine 2014

·Typhoid fever in Fiji: a reversible plague?

Thompson CN, Kama M, Acharya S, Bera U, Clemens J, Crump JA, Dawainavesi A, Dougan G, Edmunds WJ, Fox K, Jenkins K, Khan MI, Koroivueta J, Levine MM et al.,

Tropical medicine & international health : TM & IH 2014

·Genetic background of extreme violent behavior.

Tiihonen J, Rautiainen MR, Ollila HM, Repo-Tiihonen E, Virkkunen M, Palotie A, Pietiläinen O, Kristiansson K, Joukamaa M, Lauerma H, Saarela J et al.,

Molecular psychiatry 2014

·A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans.

Timpson NJ, Walter K, Min JL, Tachmazidou I, Malerba G, Shin SY, Chen L, Futema M, Southam L, Iotchkova V, Cocca M, Huang J, Memari Y, McCarthy S et al.,

Nature communications 2014;5;4871

·Faster average case low memory semi-external construction of the burrows-wheeler transform


CEUR Workshop Proceedings 2014;1146;61-68

·Simulation and estimation of gene number in a biological pathway using almost complete saturation mutagenesis screening of haploid mouse cells.

Tokunaga M, Kokubu C, Maeda Y, Sese J, Horie K, Sugimoto N, Kinoshita T, Yusa K and Takeda J

BMC genomics 2014;15;1;1016

·Complete Genome Sequences of Two Citrobacter rodentium Bacteriophages, CR8 and CR44b.

Toribio AL, Pickard D, Cerdeño-Tárraga AM, Petty NK, Thomson N, Salmond G and Dougan G

Genome announcements 2014;2;3

·New mini- zincin structures provide a minimal scaffold for members of this metallopeptidase superfamily.

Trame CB, Chang Y, Axelrod HL, Eberhardt RY, Coggill P, Punta M and Rawlings ND

BMC bioinformatics 2014;15;1;1

·Naturally Acquired Antibodies Specific for Plasmodium falciparum Reticulocyte-Binding Protein Homologue 5 Inhibit Parasite Growth and Predict Protection From Malaria.

Tran TM, Ongoiba A, Coursen J, Crosnier C, Diouf A, Huang CY, Li S, Doumbo S, Doumtabe D, Kone Y, Bathily A, Dia S, Niangaly M, Dara C, Sangala J et al.,

The Journal of infectious diseases 2014;209;5;789-98

·Summarizing specific profiles in Illumina sequencing from whole-genome amplified DNA.

Tsai IJ, Hunt M, Holroyd N, Huckvale T, Berriman M and Kikuchi T

DNA research : an international journal for rapid publication of reports o­n genes and genomes 2014;21;3;243-54

·Cellular reprogramming by transcription factor engineering.

Tsang JC, Gao X, Lu L and Liu P

Current opinion in genetics & development 2014;28C;1-9

·Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation.

Tsaprouni LG, Yang TP, Bell J, Dick KJ, Kanoni S, Nisbet J, Viñuela A, Grundberg E, Nelson CP, Meduri E, Buil A, Cambien F, Hengstenberg C, Erdmann J et al.,

Epigenetics : official journal of the DNA Methylation Society 2014;9;10;1382-96

·Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M et al.,

Science (New York, N.Y.) 2014;345;6196;1251343

·Chromosome x-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation.

Tukiainen T, Pirinen M, Sarin AP, Ladenvall C, Kettunen J, Lehtimäki T, Lokki ML, Perola M, Sinisalo J, Vlachopoulou E, Eriksson JG, Groop L, Jula A, Järvelin MR et al.,

PLoS genetics 2014;10;2;e1004127

·Human genetics: pre-Columbian Pacific contact.

Tyler-Smith C

Current biology : CB 2014;24;21;R1038-40

·Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.

Vaidya AB, Morrisey JM, Zhang Z, Das S, Daly TM, Otto TD, Spillman NJ, Wyvratt M, Siegl P, Marfurt J, Wirjanata G, Sebayang BF, Price RN, Chatterjee A et al.,

Nature communications 2014;5;5521

·Heps with pep: direct reprogramming into human hepatocytes.

Vallier L

Cell stem cell 2014;14;3;267-9

·Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.

van den Berg SM, de Moor MH, McGue M, Pettersson E, Terracciano A, Verweij KJ, Amin N, Derringer J, Esko T, van Grootheest G, Hansell NK, Huffman J, Konte B, Lahti J, Luciano M, Matteson LK, Viktorin A, Wouda J, Agrawal A, Allik J, Bierut L et al.,

Behavior genetics 2014

·TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA and Lehner PJ

Proceedings of the National Academy of Sciences of the United States of America 2014

·Cancer gene discovery goes mobile.

van der Weyden L, Ranzani M and Adams DJ

Nature genetics 2014;46;9;928-9

·In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale?

van Hal SJ, Steen JA, Espedido BA, Grimmond SM, Cooper MA, Holden MT, Bentley SD, Gosbell IB and Jensen SO

The Journal of antimicrobial chemotherapy 2014;69;2;363-7

·Common genetic variants do not associate with CAD in familial hypercholesterolemia.

van Iperen EP, Sivapalaratnam S, Boekholdt SM, Hovingh GK, Maiwald S, Tanck MW, Soranzo N, Stephens JC, Sambrook JG, Levi M, Ouwehand WH, Kastelein JJ et al.,

European journal of human genetics : EJHG 2014;22;6;809-13

·The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels.

van Leeuwen EM, Smouter FA, Kam-Thong T, Karbalai N, Smith AV, Harris TB, Launer LJ, Sitlani CM, Li G, Brody JA, Bis JC, White CC, Jaiswal A, Oostra BA et al.,

PloS o­ne 2014;9;10;e109290

·Single cell analysis of cancer genomes.

Van Loo P and Voet T

Current opinion in genetics & development 2014;24C;82-91

·The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design.

van Sorge NM, Cole JN, Kuipers K, Henningham A, Aziz RK, Kasirer-Friede A, Lin L, Berends ET, Davies MR, Dougan G, Zhang F, Dahesh S, Shaw L et al.,

Cell host & microbe 2014;15;6;729-40

·Defining the estimated core genome of bacterial populations using a bayesian decision model.

van Tonder AJ, Mistry S, Bray JE, Hill DM, Cody AJ, Farmer CL, Klugman KP, von Gottberg A, Bentley SD, Parkhill J, Jolley KA, Maiden MC and Brueggemann AB

PLoS computational biology 2014;10;8;e1003788

·Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.

Varga TV, Sonestedt E, Shungin D, Koivula RW, Hallmans G, Escher SA, Barroso I, Nilsson P, Melander O, Orho-Melander M, Renström F and Franks PW

PLoS genetics 2014;10;6;e1004388

·RNA-seq analysis of the influence of anaerobiosis and FNR o­n Shigella flexneri.

Vergara-Irigaray M, Fookes MC, Thomson NR and Tang CM

BMC genomics 2014;15;438

·Genetic diversity in Puerto Rico and its implications for the peopling of the Island and the West Indies.

Vilar MG, Melendez C, Sanders AB, Walia A, Gaieski JB, Owings AC, Schurr TG and Genographic Consortium

American journal of physical anthropology 2014;155;3;352-68

·Detecting and measuring selection from gene frequency data.

Vitalis R, Gautier M, Dawson KJ and Beaumont MA

Genetics 2014;196;3;799-817

·Identification of enterotoxigenic Escherichia coli (ETEC) clades with long-term global distribution.

von Mentzer A, Connor TR, Wieler LH, Semmler T, Iguchi A, Thomson NR, Rasko DA, Joffre E, Corander J, Pickard D, Wiklund G, Svennerholm AM, Sjöling Å and Dougan G

Nature genetics 2014;46;12;1321-6

·Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.

Würtz P, Wang Q, Kangas AJ, Richmond RC, Skarp J, Tiainen M, Tynkkynen T, Soininen P, Havulinna AS, Kaakinen M, Viikari JS, Savolainen MJ et al.,

PLoS medicine 2014;11;12;e1001765

·An outpatient, ambulant-design, controlled human infection model using escalating doses of salmonella typhi challenge delivered in sodium bicarbonate solution.

Waddington CS, Darton TC, Jones C, Haworth K, Peters A, John T, Thompson BA, Kerridge SA, Kingsley RA, Zhou L, Holt KE, Yu LM, Lockhart S, Farrar JJ et al.,

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2014;58;9;1230-40

·Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction.

Wain LV, Sayers I, Soler Artigas M, Portelli MA, Zeggini E, Obeidat M, Sin DD, Bossé Y, Nickle D, Brandsma CA, Malarstig A, Vangjeli C, Jelinsky SA, John S et al.,

PLoS genetics 2014;10;5;e1004314

·Adding genomic 'foliage' to the tree of life.

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Nature reviews. Microbiology 2014;12;2;78

·The genetic basis of plasmid tropism between Chlamydia trachomatis and Chlamydia muridarum.

Wang Y, Cutcliffe LT, Skilton RJ, Ramsey KH, Thomson NR and Clarke IN

Pathogens and disease 2014;72;1;19-23

·Voyage to the bottom of the 'seaquence'.

Wash R and Soria CD

Nature reviews. Microbiology 2014;12;9;597

·Contemporary gene flow between wild An. gambiae s.s. and An. arabiensis.

Weetman D, Steen K, Rippon EJ, Mawejje HD, Donnelly MJ and Wilding CS

Parasites & vectors 2014;7;345

·Next-generation pathogen genomics.

Weinstock GM and Peacock SJ

Genome biology 2014;15;11;528

·The OMSSAPercolator: an automated tool to validate OMSSA results.

Wen B, Li G, Wright JC, Du C, Feng Q, Xu X, Choudhary JS and Wang J

Proteomics 2014;14;9;1011-4

·A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya.

Wendler JP, Okombo J, Amato R, Miotto O, Kiara SM, Mwai L, Pole L, O'Brien J, Manske M, Alcock D, Drury E, Sanders M, Oyola SO et al.,

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·Phenotyping structural abnormalities in mouse embryos using high-resolution episcopic microscopy.

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·A membrane topology model for human interferon inducible transmembrane protein 1.

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Nucleic acids research 2014;42;8;5059-71

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Development (Cambridge, England) 2014;141;20;4018-30

·Heterozygous Loss-of-Function Mutations in YAP1 Cause Both Isolated and Syndromic Optic Fissure Closure Defects.

Williamson KA, Rainger J, Floyd JA, Ansari M, Meynert A, Aldridge KV, Rainger JK, Anderson CA, Moore AT, Hurles ME, Clarke A, van Heyningen V et al.,

American journal of human genetics 2014;94;2;295-302

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JAK-STAT 2014;3;1;e28055

·Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.

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·Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A et al.,

Cancer cell 2014;25;6;794-808

·Inactivating CUX1 mutations promote tumorigenesis.

Wong CC, Martincorena I, Rust AG, Rashid M, Alifrangis C, Alexandrov LB, Tiffen JC et al.,

Nature genetics 2014;46;1;33-8

·Defining the role of common variation in the genomic and biological architecture of adult human height.

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Nature genetics 2014

·Plasmodium falciparum Erythrocyte Invasion: Combining Function with Immune Evasion.

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Genetics 2014

·Long term conservation of human metabolic phenotypes and link to heritability.

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Metabolomics : Official journal of the Metabolomic Society 2014;10;5;1005-1017

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·A genome-wide assessment of the role of untagged copy number variants in type 1 diabetes.

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PLoS genetics 2014;10;5;e1004367

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British journal of cancer 2014

·Repeated landmass reformation limits diversification in the widespread littoral zone mosquito Anopheles sundaicus sensu lato in the Indo-Oriental Region.

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The international journal of biochemistry & cell biology 2014;46;49-55

·Transient Darwinian selection in Salmonella enterica serovar Paratyphi A during 450 years of global spread of enteric fever.

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Proceedings of the National Academy of Sciences of the United States of America 2014;111;33;12199-204



Ngày 11/08/2015
TS.BS. Huỳnh Hồng Quang  


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