Home TRANG CHỦ Thứ 3, ngày 19/03/2024
    Hỏi đáp   Diễn đàn   Sơ đồ site     Liên hệ     English
IMPE-QN
Web Sites & Commerce Giới thiệu
Web Sites & Commerce Tin tức - Sự kiện
Web Sites & Commerce Hoạt động hợp tác
Web Sites & Commerce Hoạt động đào tạo
Web Sites & Commerce Chuyên đề
Web Sites & Commerce Tư vấn sức khỏe
Web Sites & Commerce Tạp chí-Ấn phẩm
Finance & Retail Thư viện điện tử
Công trình nghiên cứu về Ký sinh trùng
Công trình nghiên cứu về Sốt rét & SXH
Công trình nghiên cứu về Côn trùng & véc tơ truyền
Đề tài NCKH đã nghiệm thu
Thông tin-Tư liệu NCKH
Web Sites & Commerce Hoạt động Đảng & Đoàn thể
Web Sites & Commerce Bạn trẻ
Web Sites & Commerce Văn bản pháp quy
Số liệu thống kê
Web Sites & Commerce An toàn thực phẩm & hóa chất
Web Sites & Commerce Thầy thuốc và Danh nhân
Web Sites & Commerce Ngành Y-Vinh dự và trách nhiệm
Web Sites & Commerce Trung tâm dịch vụ
Web Sites & Commerce Thông báo-Công khai
Web Sites & Commerce Góc thư giản

Tìm kiếm

Đăng nhập
Tên truy cập
Mật khẩu

WEBLINKS
Website liên kết khác
 
 
Số lượt truy cập:
5 2 2 0 1 1 4 0
Số người đang truy cập
1 0 0 8
 Thư viện điện tử Công trình nghiên cứu về Sốt rét & SXH
Tổng hợp các nghiên cứu về kháng thuốc sốt rét dưới góc độ phân tử

Trong thời gian qua, với xu hướng giảm thấp của bệnh nhân sốt rét, ký sinh trùng sốt rét tại hâù hết các vùng sốt rét lưu hành trên thế giới, đặc biệt tại khu vực Đông Nam châu Á và Tiểu vùng Sông Mekong (GMS), dù vậy chúng ta vẫn đang đối mặt nhiều thách thức khó khăn trong kiểm soát và loại trừ sốt rét do đang phải đối mặt nhiều vấn đề phức tạp gồm sốt rét trên dân di biến động, ký sinh trùng kháng thuốc, muỗi sốt rét tăng sức chịu đựng và kháng với hóa chất hiện dùng và dẫn giao lưu biên giới, đi rừng ngủ rẫy tại các vùng có sốt rét lưu hành nặng.

Với các biện pháp kiểm soát như hiện nay đã góp phần không nhỏ vào khống chế sót rét, bên cạnh đó vai trò của các công cụ sinh học phân tử cũng đóng vai trò then chốt và có giá trị nhất định để đánh giá tình trạng người mang ký sinh trùng không triệu chứng và ký sinh trùng hay muỗi kháng hóa chất. Dưới đây là một số nghiên cứu được thực hiện trong thời gian qua về vai trò sinh học phân tử trong lĩnh vực sốt rét.

Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant Plasmodium falciparum distributions in Southeast Asia.

Grist EP, Flegg JA, Humphreys G, Mas IS, Anderson TJ, Ashley EA, Day NP, Dhorda M, Dondorp AM, Faiz MA, Gething PW, Hien TT, Hlaing TM, Imwong M, Kindermans JM, Maude RJ, Mayxay M, McDew-White M, Menard D, Nair S, Nosten F, Newton PN, Price RN, Pukrittayakamee S, Takala-Harrison S, Smithuis F, Nguyen NT, Tun KM, White NJ, Witkowski B, Woodrow CJ, Fairhurst RM, Sibley CH, Guerin PJ.

Int J Health Geogr. 2016 Oct 24;15(1):37.

PMID: 27776514 Free PMC Article

Lack of artemisinin resistance in Plasmodium falciparum in northwest Benin after 10 years of use of artemisinin-based combination therapy.

Ogouyèmi-Hounto A, Damien G, Deme AB, Ndam NT, Assohou C, Tchonlin D, Mama A, Hounkpe VO, Moutouama JD, Remoué F, Ndiaye D, Gazard DK.

Parasite. 2016;23:28. doi: 10.1051/parasite/2016028. Epub 2016 Jul 21.

PMID: 27443837 Free PMC Article


Hình 1

Polymorphisms of the artemisinin resistant marker (K13) in Plasmodium falciparum parasite populations of Grande Comore Island 10 years after artemisinin combination therapy.

Huang B, Deng C, Yang T, Xue L, Wang Q, Huang S, Su XZ, Liu Y, Zheng S, Guan Y, Xu Q, Zhou J, Yuan J, Bacar A, Abdallah KS, Attoumane R, Mliva AM, Zhong Y, Lu F, Song J.

Parasit Vectors. 2015 Dec 15;8:634. doi: 10.1186/s13071-015-1253-z.

PMID:

26667053

Free PMC Article

Similar articles

Select item 250646144.

The challenge of artemisinin resistance can o­nly be met by eliminating Plasmodium falciparum malaria across the Greater Mekong subregion.

Smith Gueye C, Newby G, Hwang J, Phillips AA, Whittaker M, MacArthur JR, Gosling RD, Feachem RG.

Malar J. 2014 Jul 27;13:286. doi: 10.1186/1475-2875-13-286.

PMID: 25064614 Free PMC Article

Artemisinin resistance-associated polymorphisms at the K13-propeller locus are absent in Plasmodium falciparum isolates from Haiti.

Carter TE, Boulter A, Existe A, Romain JR, St Victor JY, Mulligan CJ, Okech BA.

Am J Trop Med Hyg. 2015 Mar;92(3):552-4. doi: 10.4269/ajtmh.14-0664. Epub 2015 Feb 2.

PMID: 25646258 Free PMC Article


Hình 2

Artemisinin resistance--the clock is ticking.

White NJ.

Lancet. 2010 Dec 18;376(9758):2051-2. doi: 10.1016/S0140-6736(10)61963-0. No abstract available.

PMID: 21168039 Similar articles

Novel mutations in K13 propeller gene of artemisinin-resistant Plasmodium falciparum.

Isozumi R, Uemura H, Kimata I, Ichinose Y, Logedi J, Omar AH, Kaneko A.

Emerg Infect Dis. 2015 Mar;21(3):490-2. doi: 10.3201/eid2103.140898.

PMID: 25695257 Free PMC Article

The threat of artemisinin resistant malaria in Southeast Asia.

Hanboonkunupakarn B, White NJ.

Travel Med Infect Dis. 2016 Nov - Dec;14(6):548-550. doi: 10.1016/j.tmaid.2016.11.016. Epub 2016 Nov 30. No abstract available.

PMID: 27915001 Free PMC Article


Hình 3

The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread.

Woodrow CJ, White NJ.

FEMS Microbiol Rev. 2017 Jan;41(1):34-48. doi: 10.1093/femsre/fuw037. Epub 2016 Sep 8. Review.

PMID: 27613271 Free PMC Article

Vector control to eliminate artemisinin resistant malaria in the Greater Mekong subregion.

Kolaczinski J, Macdonald M, Meek S.

Lancet Infect Dis. 2014 Jan;14(1):9-11. doi: 10.1016/S1473-3099(13)70320-7. No abstract available.

PMID: 24355026 Similar articles

[Artemisinin resistance in Plasmodium falciparum: global status and basic research].

Zhao SM, Wang MY.

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2014 Oct;32(5):380-4. Review. Chinese.

PMID: 25726605 Similar articles

A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.

Ménard D, Khim N, Beghain J, Adegnika AA, Shafiul-Alam M, Amodu O, Rahim-Awab G, Barnadas C, Berry A, Boum Y, Bustos MD, Cao J, Chen JH, Collet L, Cui L, Thakur GD, Dieye A, Djallé D, Dorkenoo MA, Eboumbou-Moukoko CE, Espino FE, Fandeur T, Ferreira-da-Cruz MF, Fola AA, Fuehrer HP, Hassan AM, Herrera S, Hongvanthong B, Houzé S, Ibrahim ML, Jahirul-Karim M, Jiang L, Kano S, Ali-Khan W, Khanthavong M, Kremsner PG, Lacerda M, Leang R, Leelawong M, Li M, Lin K, Mazarati JB, Ménard S, Morlais I, Muhindo-Mavoko H, Musset L, Na-Bangchang K, Nambozi M, Niaré K, Noedl H, Ouédraogo JB, Pillai DR, Pradines B, Quang-Phuc B, Ramharter M, Randrianarivelojosia M, Sattabongkot J, Sheikh-Omar A, Silué KD, Sirima SB, Sutherland C, Syafruddin D, Tahar R, Tang LH, Touré OA, Tshibangu-wa-Tshibangu P, Vigan-Womas I, Warsame M, Wini L, Zakeri S, Kim S, Eam R, Berne L, Khean C, Chy S, Ken M, Loch K, Canier L, Duru V, Legrand E, Barale JC, Stokes B, Straimer J, Witkowski B, Fidock DA, Rogier C, Ringwald P, Ariey F, Mercereau-Puijalon O; KARMA Consortium.

N Engl J Med. 2016 Jun 23;374(25):2453-64. doi: 10.1056/NEJMoa1513137.

PMID: 27332904 Free PMC Article

How genomics is contributing to the fight against artemisinin-resistant malaria parasites.

Cravo P, Napolitano H, Culleton R.

Acta Trop. 2015 Aug;148:1-7. doi: 10.1016/j.actatropica.2015.04.007. Epub 2015 Apr 21. Review.

PMID: 25910626

Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study.

Bosman P, Stassijns J, Nackers F, Canier L, Kim N, Khim S, Alipon SC, Chuor Char M, Chea N, Dysoley L, Van den Bergh R, Etienne W, De Smet M, Ménard D, Kindermans JM.

Malar J. 2014 Oct 6;13:394. doi: 10.1186/1475-2875-13-394.

PMID: 25288380 Free PMC Article

Fighting drug-resistant Plasmodium falciparum: the challenge of artemisinin resistance.

Wongsrichanalai C, Sibley CH.

Clin Microbiol Infect. 2013 Oct;19(10):908-16. doi: 10.1111/1469-0691.12316. Epub 2013 Sep 3. Review.

PMID: 24033691 Free Article

K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa.

Kamau E, Campino S, Amenga-Etego L, Drury E, Ishengoma D, Johnson K, Mumba D, Kekre M, Yavo W, Mead D, Bouyou-Akotet M, Apinjoh T, Golassa L, Randrianarivelojosia M, Andagalu B, Maiga-Ascofare O, Amambua-Ngwa A, Tindana P, Ghansah A, MacInnis B, Kwiatkowski D, Djimde AA.

J Infect Dis. 2015 Apr 15;211(8):1352-5. doi: 10.1093/infdis/jiu608. Epub 2014 Nov 2. Erratum in: J Infect Dis. 2016 Jan 15;213(2):327.

PMID: 25367300 Free PMC Article

Absence of putative artemisinin resistance mutations among Plasmodium falciparum in Sub-Saharan Africa: a molecular epidemiologic study.

Taylor SM, Parobek CM, DeConti DK, Kayentao K, Coulibaly SO, Greenwood BM, Tagbor H, Williams J, Bojang K, Njie F, Desai M, Kariuki S, Gutman J, Mathanga DP, Mårtensson A, Ngasala B, Conrad MD, Rosenthal PJ, Tshefu AK, Moormann AM, Vulule JM, Doumbo OK, Ter Kuile FO, Meshnick SR, Bailey JA, Juliano JJ.

J Infect Dis. 2015 Mar 1;211(5):680-8. doi: 10.1093/infdis/jiu467. Epub 2014 Sep 1.

PMID: 25180240 Free PMC Article

Natural selection of K13 mutants of Plasmodium falciparum in response to artemisinin combination therapies in Thailand.

Putaporntip C, Kuamsab N, Kosuwin R, Tantiwattanasub W, Vejakama P, Sueblinvong T, Seethamchai S, Jongwutiwes S, Hughes AL.

Clin Microbiol Infect. 2016 Mar;22(3):285.e1-8. doi: 10.1016/j.cmi.2015.10.027. Epub 2015 Nov 5.

PMID: 26548510 Free Article

Plasmodium falciparum malaria: Convergent evolutionary trajectories towards delayed clearance following artemisinin treatment.

Wilairat P, Kümpornsin K, Chookajorn T.

Med Hypotheses. 2016 May;90:19-22. doi: 10.1016/j.mehy.2016.02.022. Epub 2016 Mar 4.

PMID: 27063079 Similar articles

The spread of artemisinin-resistant Plasmodium falciparum in the Greater Mekong subregion: a molecular epidemiology observational study.

Imwong M, Suwannasin K, Kunasol C, Sutawong K, Mayxay M, Rekol H, Smithuis FM, Hlaing TM, Tun KM, van der Pluijm RW, Tripura R, Miotto O, Menard D, Dhorda M, Day NPJ, White NJ, Dondorp AM.

Lancet Infect Dis. 2017 May;17(5):491-497. doi: 10.1016/S1473-3099(17)30048-8. Epub 2017 Feb 2.

PMID: 28161569 Free PMC Article

Limited polymorphisms in k13 gene in Plasmodium falciparum isolates from Dakar, Senegal in 2012-2013.

Torrentino-Madamet M, Fall B, Benoit N, Camara C, Amalvict R, Fall M, Dionne P, Ba Fall K, Nakoulima A, Diatta B, Diemé Y, Ménard D, Wade B, Pradines B.

Malar J. 2014 Dec 4;13:472. doi: 10.1186/1475-2875-13-472.

PMID: 25471113 Free PMC Article

Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates.

Straimer J, Gnädig NF, Witkowski B, Amaratunga C, Duru V, Ramadani AP, Dacheux M, Khim N, Zhang L, Lam S, Gregory PD, Urnov FD, Mercereau-Puijalon O, Benoit-Vical F, Fairhurst RM, Ménard D, Fidock DA.

Science. 2015 Jan 23;347(6220):428-31. doi: 10.1126/science.1260867. Epub 2014 Dec 11.

PMID: 25502314 Free PMC Article

Assessing the asymptomatic reservoir and dihydroartemisinin-piperaquine effectiveness in a low transmission setting threatened by artemisinin resistant Plasmodium falciparum.

Falq G, Van Den Bergh R, De Smet M, Etienne W, Nguon C, Rekol H, Imwong M, Dondorp A, Kindermans JM.

Malar J. 2016 Sep 1;15(1):446. doi: 10.1186/s12936-016-1487-z.

PMID: 27585957 Free PMC Article

Insight into k13-propeller gene polymorphism and ex vivo DHA-response profiles from Cameroonian isolates.

Menard S, Tchoufack JN, Maffo CN, Nsango SE, Iriart X, Abate L, Tsapi MT, Awono-Ambéné PH, Abega Mekongo FA, Morlais I, Berry A.

Malar J. 2016 Nov 26;15(1):572.

PMID: 27887614 Free PMC Article

Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance.

Mita T, Tanabe K.

Jpn J Infect Dis. 2012;65(6):465-75. Review.

PMID: 23183197 Free Article

Plasmodium falciparum kelch 13: a potential molecular marker for tackling artemisinin-resistant malaria parasites.

Mita T, Tachibana S, Hashimoto M, Hirai M.

Expert Rev Anti Infect Ther. 2016;14(1):125-35. doi: 10.1586/14787210.2016.1106938. Epub 2015 Nov 4. Review.

PMID: 26535806 Similar articles

Selection and spread of artemisinin-resistant alleles in Thailand prior to the global artemisinin resistance containment campaign.

Talundzic E, Okoth SA, Congpuong K, Plucinski MM, Morton L, Goldman IF, Kachur PS, Wongsrichanalai C, Satimai W, Barnwell JW, Udhayakumar V.

PLoS Pathog. 2015 Apr 2;11(4):e1004789. doi: 10.1371/journal.ppat.1004789. eCollection 2015 Apr. Erratum in: PLoS Pathog. 2015 Apr;11(4):e1004862.

PMID: 25836766 Free PMC Article

How to Contain Artemisinin- and Multidrug-Resistant Falciparum Malaria.

Dondorp AM, Smithuis FM, Woodrow C, Seidlein LV.

Trends Parasitol. 2017 May;33(5):353-363. doi: 10.1016/j.pt.2017.01.004. Epub 2017 Feb 7. Review.

PMID: 28187990 Free Article

The threat of artemisinin-resistant malaria.

Dondorp AM, Fairhurst RM, Slutsker L, Macarthur JR, Breman JG, Guerin PJ, Wellems TE, Ringwald P, Newman RD, Plowe CV.

N Engl J Med. 2011 Sep 22;365(12):1073-5. doi: 10.1056/NEJMp1108322. No abstract available.

PMID: 21992120 Free PMC Article

Artemisinin Resistance-Associated K13 Polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010-2015.

Tacoli C, Gai PP, Bayingana C, Sifft K, Geus D, Ndoli J, Sendegeya A, Gahutu JB, Mockenhaupt FP.

Am J Trop Med Hyg. 2016 Nov 2;95(5):1090-1093. Epub 2016 Aug 29.

PMID: 27573632 Free PMC Article

Mekong malaria. Malaria, multi-drug resistance and economic development in the greater Mekong subregion of Southeast Asia.

Singhasivanon P.

Southeast Asian J Trop Med Public Health. 1999;30 Suppl 4:i-iv, 1-101.

PMID: 10935286 Similar articles

Genomic epidemiology of artemisinin resistant malaria.

MalariaGEN Plasmodium falciparum Community Project.

Elife. 2016 Mar 4;5. pii: e08714. doi: 10.7554/eLife.08714.

PMID:

26943619

Free PMC Article

Similar articles

Select item 2680190933.

Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children.

Muwanguzi J, Henriques G, Sawa P, Bousema T, Sutherland CJ, Beshir KB.

Malar J. 2016 Jan 22;15:36. doi: 10.1186/s12936-016-1095-y.

PMID: 26801909 Free PMC Article

Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011-2013.

Hawkes M, Conroy AL, Opoka RO, Namasopo S, Zhong K, Liles WC, John CC, Kain KC.

Emerg Infect Dis. 2015 Jul;21(7):1237-9. doi: 10.3201/eid2107.150213.

PMID: 26079933 Free PMC Article

Artemisinin derivatives and malaria: useful, in combination with other antimalarials.

[No authors listed]

Prescrire Int. 2008 Aug;17(96):162-8.

PMID: 19492494 Similar articles

Polymorphisms in K13 and falcipain-2 associated with artemisinin resistance are not prevalent in Plasmodium falciparum isolated from Ugandan children.

Conrad MD, Bigira V, Kapisi J, Muhindo M, Kamya MR, Havlir DV, Dorsey G, Rosenthal PJ.

PLoS o­ne. 2014 Aug 21;9(8):e105690. doi: 10.1371/journal.pone.0105690. eCollection 2014.

PMID: 25144768 Free PMC Article

Artemisinin resistance at the China-Myanmar border and association with mutations in the K13 propeller gene.

Wang Z, Wang Y, Cabrera M, Zhang Y, Gupta B, Wu Y, Kemirembe K, Hu Y, Liang X, Brashear A, Shrestha S, Li X, Miao J, Sun X, Yang Z, Cui L.

Antimicrob Agents Chemother. 2015 Nov;59(11):6952-9. doi: 10.1128/AAC.01255-15. Epub 2015 Aug 31.

PMID: 26324266 Free PMC Article

An outbreak of artemisinin resistant falciparum malaria in Eastern Thailand.

Imwong M, Jindakhad T, Kunasol C, Sutawong K, Vejakama P, Dondorp AM.

Sci Rep. 2015 Nov 30;5:17412. doi: 10.1038/srep17412.

PMID: 26616851 Free PMC Article

Monitoring for Plasmodium falciparum drug resistance to artemisinin and artesunate in Binh Phuoc Province, Vietnam: 1998-2009.

Thanh NV, Toan TQ, Cowman AF, Casey GJ, Phuc BQ, Tien NT, Hung NM, Biggs BA.

Malar J. 2010 Jun 24;9:181. doi: 10.1186/1475-2875-9-181.

PMID: 20573274 Free PMC Article

The last man standing is the most resistant: eliminating artemisinin-resistant malaria in Cambodia.

Maude RJ, Pontavornpinyo W, Saralamba S, Aguas R, Yeung S, Dondorp AM, Day NP, White NJ, White LJ.

Malar J. 2009 Feb 20;8:31. doi: 10.1186/1475-2875-8-31.

PMID: 19228438 Free PMC Article

Plasmodium falciparum Resistance to Artemisinin Derivatives and Piperaquine: A Major Challenge for Malaria Elimination in Cambodia.

Duru V, Witkowski B, Ménard D.

Am J Trop Med Hyg. 2016 Dec 7;95(6):1228-1238. Epub 2016 Oct 17. Review.

PMID: 27928074 Free PMC Article

K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar.

Win AA, Imwong M, Kyaw MP, Woodrow CJ, Chotivanich K, Hanboonkunupakarn B, Pukrittayakamee S.

Malar J. 2016 Feb 24;15:110. doi: 10.1186/s12936-016-1147-3. Erratum in: Malar J. 2016;15(1):297.

PMID: 26911145 Free PMC Article

Monitoring antimalarial drug efficacy in the Greater Mekong Subregion: an overview of in vivo results from 2008 to 2010.

Bustos MD, Wongsrichanalai C, Delacollette C, Burkholder B.

Southeast Asian J Trop Med Public Health. 2013;44 Suppl 1:201-30; discussion 306-7. Review.

PMID: 24159833 Similar articles

Detection of artemisinin-resistant Plasmodium falciparum in malarial infection: a brief review of methods.

Quashie NB.

J Trop Pediatr. 2010 Apr;56(2):119-21. doi: 10.1093/tropej/fmp074. Epub 2009 Aug 5. Review.

PMID: 19656841 Similar articles

Challenges and prospects for malaria elimination in the Greater Mekong Subregion.

Cui L, Yan G, Sattabongkot J, Chen B, Cao Y, Fan Q, Parker D, Sirichaisinthop J, Su XZ, Yang H, Yang Z, Wang B, Zhou G.

Acta Trop. 2012 Mar;121(3):240-5. doi: 10.1016/j.actatropica.2011.04.006. Epub 2011 Apr 14.

PMID: 21515238 Free PMC Article

Rapid and effective malaria control in Cambodia through mass administration of artemisinin-piperaquine.

Song J, Socheat D, Tan B, Dara P, Deng C, Sokunthea S, Seila S, Ou F, Jian H, Li G.

Malar J. 2010 Feb 23;9:57. doi: 10.1186/1475-2875-9-57.

PMID: 20175930 Free PMC Article

The emerging threat of artemisinin resistance in malaria: focus o­n artemether-lumefantrine.

Djimde AA, Makanga M, Kuhen K, Hamed K.

Expert Rev Anti Infect Ther. 2015 Aug;13(8):1031-45. doi: 10.1586/14787210.2015.1052793. Epub 2015 Jun 16. Review.

PMID: 26081265 Similar articles

Molecular assessment of artemisinin resistance markers, polymorphisms in the k13 propeller, and a multidrug-resistance gene in the eastern and western border areas of Myanmar.

Nyunt MH, Hlaing T, Oo HW, Tin-Oo LL, Phway HP, Wang B, Zaw NN, Han SS, Tun T, San KK, Kyaw MP, Han ET.

Clin Infect Dis. 2015 Apr 15;60(8):1208-15. doi: 10.1093/cid/ciu1160. Epub 2014 Dec 23.

PMID: 25537878 Similar articles

Current status of artemisinin-resistant falciparum malaria in South Asia: a randomized controlled artesunate monotherapy trial in Bangladesh.

Starzengruber P, Swoboda P, Fuehrer HP, Khan WA, Hofecker V, Siedl A, Fally M, Graf O, Teja-Isavadharm P, Haque R, Ringwald P, Noedl H.

PLoS o­ne. 2012;7(12):e52236. doi: 10.1371/journal.pone.0052236. Epub 2012 Dec 18.

PMID: 23272227 Free PMC Article

Artemisinin resistance: how can we find it?

Noedl H.

Trends Parasitol. 2005 Sep;21(9):404-5. No abstract available.

PMID: 16046187 Similar articles

Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum.

O'Brien C, Henrich PP, Passi N, Fidock DA.

Curr Opin Infect Dis. 2011 Dec;24(6):570-7. doi: 10.1097/QCO.0b013e32834cd3ed. Review.

PMID: 22001944 Free PMC Article

Independent Emergence of the Plasmodium falciparum Kelch Propeller Domain Mutant Allele C580Y in Guyana.

Chenet SM, Akinyi Okoth S, Huber CS, Chandrabose J, Lucchi NW, Talundzic E, Krishnalall K, Ceron N, Musset L, Macedo de Oliveira A, Venkatesan M, Rahman R, Barnwell JW, Udhayakumar V.

J Infect Dis. 2016 May 1;213(9):1472-5. doi: 10.1093/infdis/jiv752. Epub 2015 Dec 21.

PMID: 26690347

Molecular surveillance of antimalarial drug resistance related genes in Plasmodium falciparum isolates from Eritrea.

Menegon M, Nurahmed AM, Talha AA, Nour BY, Severini C.

Acta Trop. 2016 May;157:158-61. doi: 10.1016/j.actatropica.2016.02.007. Epub 2016 Feb 11.

PMID: 26875763 Similar articles

Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure.

Ménard S, Ben Haddou T, Ramadani AP, Ariey F, Iriart X, Beghain J, Bouchier C, Witkowski B, Berry A, Mercereau-Puijalon O, Benoit-Vical F.

Emerg Infect Dis. 2015 Oct;21(10):1733-41. doi: 10.3201/eid2110.150682.

PMID: 26401601 Free PMC Article

Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based o­n Parasitological and Molecular Assays.

Cooper RA, Conrad MD, Watson QD, Huezo SJ, Ninsiima H, Tumwebaze P, Nsobya SL, Rosenthal PJ.

Antimicrob Agents Chemother. 2015 Aug;59(8):5061-4. doi: 10.1128/AAC.00921-15. Epub 2015 Jun 1.

PMID: 26033725 Free PMC Article

Artemisinin resistance containment project in Thailand. (I): Implementation of electronic-based malaria information system for early case detection and individual case management in provinces along the Thai-Cambodian border.

Khamsiriwatchara A, Sudathip P, Sawang S, Vijakadge S, Potithavoranan T, Sangvichean A, Satimai W, Delacollette C, Singhasivanon P, Lawpoolsri S, Kaewkungwal J.

Malar J. 2012 Jul 29;11:247. doi: 10.1186/1475-2875-11-247.

PMID: 22839508 Free PMC Article

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa.

Lu F, Culleton R, Zhang M, Ramaprasad A, von Seidlein L, Zhou H, Zhu G, Tang J, Liu Y, Wang W, Cao Y, Xu S, Gu Y, Li J, Zhang C, Gao Q, Menard D, Pain A, Yang H, Zhang Q, Cao J.

N Engl J Med. 2017 Mar 9;376(10):991-3. doi: 10.1056/NEJMc1612765. Epub 2017 Feb 22. No abstract available.

PMID: 28225668 Free Article

Is the A578S Single-Nucleotide Polymorphism in K13-propeller a Marker of Emerging Resistance to Artemisinin Among Plasmodium falciparum in Africa?

Maïga-Ascofaré O, May J.

J Infect Dis. 2016 Jan 1;213(1):165-6. doi: 10.1093/infdis/jiv414. Epub 2015 Aug 12. No abstract available.

PMID: 26268852 Similar articles

The benefits of artemisinin combination therapy for malaria extend beyond the individual patient.

Garner P, Graves PM.

PLoS Med. 2005 Apr;2(4):e105. Epub 2005 Apr 26. No abstract available.

PMID: 15839750 Free PMC Article

Observing in real time the evolution of artemisinin resistance in Plasmodium falciparum.

Sibley CH.

BMC Med. 2015 Mar 31;13:67. doi: 10.1186/s12916-015-0316-5.

PMID: 25889405 Free PMC Article

Parasite clearance rates in Upper Myanmar indicate a distinctive artemisinin resistance phenotype: a therapeutic efficacy study.

Tun KM, Jeeyapant A, Imwong M, Thein M, Aung SS, Hlaing TM, Yuentrakul P, Promnarate C, Dhorda M, Woodrow CJ, Dondorp AM, Ashley EA, Smithuis FM, White NJ, Day NP.

Malar J. 2016 Mar 31;15:185. doi: 10.1186/s12936-016-1240-7.

PMID: 27036739 Free PMC Article

Evaluation of community-based systems for the surveillance of day three-positive Plasmodium falciparum cases in Western Cambodia.

Cox J, Dy Soley L, Bunkea T, Sovannaroth S, Soy Ty K, Ngak S, Bjorge S, Ringwald P, Mellor S, Sintasath D, Meek S.

Malar J. 2014 Jul 22;13:282. doi: 10.1186/1475-2875-13-282.

PMID: 25052222 Free PMC Article

Drug resistance genomics of the antimalarial drug artemisinin.

Winzeler EA, Manary MJ.

Genome Biol. 2014 Nov 25;15(11):544. doi: 10.1186/s13059-014-0544-6. Review.

PMID: 25470531 Free PMC Article

Travellers as sentinels: Assaying the worldwide distribution of polymorphisms associated with artemisinin combination therapy resistance in Plasmodium falciparum using malaria cases imported into Scotland.

Hunja CW, Unger H, Ferreira PE, Lumsden R, Morris S, Aman R, Alexander C, Mita T, Culleton R.

Int J Parasitol. 2013 Oct;43(11):885-9. doi: 10.1016/j.ijpara.2013.07.001. Epub 2013 Jul 27.

PMID: 23899818 Similar articles

In Vitro and Molecular Surveillance for Antimalarial Drug Resistance in Plasmodium falciparum Parasites in Western Kenya Reveals Sustained Artemisinin Sensitivity and Increased Chloroquine Sensitivity.

Lucchi NW, Komino F, Okoth SA, Goldman I, o­nyona P, Wiegand RE, Juma E, Shi YP, Barnwell JW, Udhayakumar V, Kariuki S.

Antimicrob Agents Chemother. 2015 Dec;59(12):7540-7. doi: 10.1128/AAC.01894-15. Epub 2015 Sep 21.

PMID: 26392510 Free PMC Article

A Single Mutation in K13 Predominates in Southern China and Is Associated With Delayed Clearance of Plasmodium falciparum Following Artemisinin Treatment.

Huang F, Takala-Harrison S, Jacob CG, Liu H, Sun X, Yang H, Nyunt MM, Adams M, Zhou S, Xia Z, Ringwald P, Bustos MD, Tang L, Plowe CV.

J Infect Dis. 2015 Nov 15;212(10):1629-35. doi: 10.1093/infdis/jiv249. Epub 2015 Apr 24.

PMID: 25910630 Free PMC Article

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria.

Mbengue A, Bhattacharjee S, Pandharkar T, Liu H, Estiu G, Stahelin RV, Rizk SS, Njimoh DL, Ryan Y, Chotivanich K, Nguon C, Ghorbal M, Lopez-Rubio JJ, Pfrender M, Emrich S, Mohandas N, Dondorp AM, Wiest O, Haldar K.

Nature. 2015 Apr 30;520(7549):683-7. doi: 10.1038/nature14412. Epub 2015 Apr 15.

PMID: 25874676 Free PMC Article

Artemisinin resistance in Plasmodium falciparum: what is it really?

Ferreira PE, Culleton R, Gil JP, Meshnick SR.

Trends Parasitol. 2013 Jul;29(7):318-20. doi: 10.1016/j.pt.2013.05.002. Epub 2013 Jun 11.

PMID: 23768531

Artemisinin-resistant malaria in Asia.

Noedl H, Socheat D, Satimai W.

N Engl J Med. 2009 Jul 30;361(5):540-1. doi: 10.1056/NEJMc0900231. No abstract available.

PMID: 19641219 Free Article

[More artemisinin-resistant malaria in Thailand].

Holen Ø.

Tidsskr Nor Laegeforen. 2012 May 29;132(10):1223. Norwegian. No abstract available.

PMID: 22855939 Similar articles

A crucial piece in the puzzle of the artemisinin resistance mechanism in Plasmodium falciparum.

Bozdech Z, Ferreira PE, Mok S.

Trends Parasitol. 2015 Aug;31(8):345-6. doi: 10.1016/j.pt.2015.06.004. Epub 2015 Jul 11.

PMID: 26169358 Similar articles

Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study.

Spring MD, Lin JT, Manning JE, Vanachayangkul P, Somethy S, Bun R, Se Y, Chann S, Ittiverakul M, Sia-ngam P, Kuntawunginn W, Arsanok M, Buathong N, Chaorattanakawee S, Gosi P, Ta-aksorn W, Chanarat N, Sundrakes S, Kong N, Heng TK, Nou S, Teja-isavadharm P, Pichyangkul S, Phann ST, Balasubramanian S, Juliano JJ, Meshnick SR, Chour CM, Prom S, Lanteri CA, Lon C, Saunders DL.

Lancet Infect Dis. 2015 Jun;15(6):683-91. doi: 10.1016/S1473-3099(15)70049-6. Epub 2015 Apr 12.

PMID: 25877962 Similar articles

[Plasmodium falciparum resistance to artemisinin-based combination therapies (ACTs): Fears of widespread drug resistance].

Benoit-Vical F, Paloque L, Augereau JM.

Bull Acad Natl Med. 2016 Mar;200(3):477-89; discussion 490. Review. French.

PMID: 28644374 Similar articles

The development of artemisinin resistance in malaria: reasons and solutions.

Chrubasik C, Jacobson RL.

Phytother Res. 2010 Jul;24(7):1104-6. doi: 10.1002/ptr.3133.

PMID: 20578122 Similar articles

Mutation analysis in pfmdr1 and pfmrp1 as potential candidate genes for artemisinin resistance in Plasmodium falciparum clinical isolates 4years after implementation of artemisinin combination therapy in Iran.

Pirahmadi S, Zakeri S, Afsharpad M, Djadid ND.

Infect Genet Evol. 2013 Mar;14:327-34. doi: 10.1016/j.meegid.2012.12.014. Epub 2012 Dec 31.

PMID: 23287027 Similar articles

Updates o­n k13 mutant alleles for artemisinin resistance in Plasmodium falciparum.

Zaw MT, Emran NA, Lin Z.

J Microbiol Immunol Infect. 2018 Apr;51(2):159-165. doi: 10.1016/j.jmii.2017.06.009. Epub 2017 Jun 29. Review.

PMID: 28711439 Free Article

More insights into the pharmacological effects of artemisinin.

Zyad A, Tilaoui M, Jaafari A, Oukerrou MA, Mouse HA.

Phytother Res. 2018 Feb;32(2):216-229. doi: 10.1002/ptr.5958. Epub 2017 Nov 28. Review.

PMID: 29193409 Similar articles

Quantifying aggregated uncertainty in Plasmodium falciparum malaria prevalence and populations at risk via efficient space-time geostatistical joint simulation.

Gething PW, Patil AP, Hay SI.

PLoS Comput Biol. 2010 Apr 1;6(4):e1000724. doi: 10.1371/journal.pcbi.1000724.

PMID: 20369009 Free PMC Article

Multidrug-resistant Plasmodium falciparum malaria in the Greater Mekong subregion.

Ménard D, Clain J, Ariey F.

Lancet Infect Dis. 2018 Mar;18(3):238-239. doi: 10.1016/S1473-3099(18)30071-9. Epub 2018 Feb 2. No abstract available.

PMID: 29398389 Free Article

Ngày 01/05/2018
TS.BS. Huỳnh Hồng Quang  

THÔNG BÁO

   Dịch vụ khám chữa bệnh chuyên khoa của Viện Sốt rét-KST-CT Quy Nhơn khám bệnh tất cả các ngày trong tuần (kể cả thứ 7 và chủ nhật)

   THÔNG BÁO: Phòng khám chuyên khoa Viện Sốt rét-KST-CT Quy Nhơn xin trân trọng thông báo thời gian mở cửa hoạt động trở lại vào ngày 20/10/2021.


 LOẠI HÌNH DỊCH VỤ
 CHUYÊN ĐỀ
 PHẦN MỀM LIÊN KẾT
 CÁC VẤN ĐỀ QUAN TÂM
 QUẢNG CÁO

Trang tin điện tử Viện Sốt rét - Ký Sinh trùng - Côn trùng Quy Nhơn
Giấy phép thiết lập số 53/GP - BC do Bộ văn hóa thông tin cấp ngày 24/4/2005
Địa chỉ: Khu vực 8-Phường Nhơn Phú-Thành phố Quy Nhơn-Tỉnh Bình Định.
Tel: (84) 0256.3846.892 - Fax: (84) 0256.3647464
Email: impequynhon.org.vn@gmail.com
Trưởng Ban biên tập: TTND.PGS.TS. Hồ Văn Hoàng-Viện trưởng
Phó Trưởng ban biên tập: TS.BS.Huỳnh Hồng Quang-Phó Viện trưởng
• Thiết kế bởi công ty cổ phần phần mềm: Quảng Ích