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Phần 2: Cập nhật thông tin về nghiên cứu ấu trùng giun đũa chó mèo Toxocara spp. gây bệnh ở người

Trong thời gian 5 năm trở lại đây, bệnh do lây truyền từ động vật sang người ngày càng trở nên phổ biến với tần suất gặp trên lâm sàng ngày càng tăng, một trong những căn bệnh đó là bệnh do ấu trùng giun đũa chó/ mèo Toxocara canis Toxocara cati. Nhiều nghiên cứu trên thế giới và Việt Nam đã và đang tiếp tục triển khai trên cộng đồng và trong cơ ở bệnh viện. Nhân đây, chúng tôi xin chia sẻ một số công trình nghiên cứu về bệnh này trong thời gian qua.

An improved method to obtain antigen-excreting Toxocara canis larvae.

Alcântara-Neves NM, dos Santos AB, Mendonça LR, Figueiredo CA, Pontes-de-Carvalho L.

Exp Parasitol. 2008 Jul;119(3):349-51. doi: 10.1016/j.exppara.2008.03.006. Epub 2008 Mar 23.

PMID: 18439580 Similar articles Select item 244269326.

Species-specific and common epitopes o­n the secreted and surface antigens of Toxocara cati and Toxocara canis infective larvae.

Kennedy MW, Maizels RM, Meghji M, Young L, Qureshi F, Smith HV.

Parasite Immunol. 1987 Jul;9(4):407-20.

PMID: 2442693 Similar articles Select item 1269503927.

Infectivity and pathogenicity of 14-month-cultured embryonated eggs of Toxocara canis in mice.

Fan CK, Lin YH, Du WY, Su KE.

Vet Parasitol. 2003 Apr 18;113(2):145-55.

PMID: 12695039 Similar articles Select item 2859155528.


Hình 1

Seroepidemiological study and associated risk factors of Toxocara canis infection among preschool children in Osun State, Nigeria.

Sowemimo OA, Lee YL, Asaolu SO, Chuang TW, Akinwale OP, Badejoko BO, Gyang VP, Nwafor T, Henry E, Fan CK.

Acta Trop. 2017 Sep;173:85-89. doi: 10.1016/j.actatropica.2017.05.030. Epub 2017 Jun 4.

PMID: 28591555 Similar articles Select item 2329027929.

Factors affecting disease manifestation of toxocarosis in humans: genetics and environment.

Fan CK, Liao CW, Cheng YC.

Vet Parasitol. 2013 Apr 15;193(4):342-52. doi: 10.1016/j.vetpar.2012.12.030. Epub 2012 Dec 20.

PMID: 23290279 Free Article Similar articles Select item 965733230.


Hình 2

Characterisation of Tc-cpl-1, a cathepsin L-like cysteine protease from Toxocara canis infective larvae.

Loukas A, Selzer PM, Maizels RM.

Mol Biochem Parasitol. 1998 May 1;92(2):275-89.

PMID: 9657332 Similar articles Select item 1791518631.

Evaluation of follow-up of therapy with fenbendazole incorporated into stabilized liposomes and immunomodulator glucan in mice infected with Toxocara canis larvae.

Hrckova G, Velebný S, Obwaller A, Auer H, Kogan G.

Acta Trop. 2007 Nov-Dec;104(2-3):122-32. Epub 2007 Aug 26.

PMID: 17915186 Similar articles Select item 1141280432.

A cDNA encoding Tc-MUC-5, a mucin from Toxocara canis larvae identified by expression screening.

Doedens A, Loukas A, Maizels RM.

Acta Trop. 2001 Jun 22;79(3):211-7.

PMID: 11412804 Similar articles Select item 2263488633.

IgG antibody responses in mice coinfected with Toxocara canis and other helminths or protozoan parasites.

Lescano SA, Nakhle MC, Ribeiro MC, Chieffi PP.

Rev Inst Med Trop Sao Paulo. 2012 May-Jun;54(3):145-52.

PMID: 22634886 Free Article Similar articles Select item 754102534.

Idiotypic replica of a Toxocara canis excretory/secretory antigen epitope.

Bardon R, Guillen JL, Aguila C.

Int J Parasitol. 1995 Jan;25(1):105-11.

PMID: 7541025 Similar articles Select item 2903586335.


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Sero-detection of Toxocara canis infection in human with T.canis recombinant arginine kinase, cathepsin L-1 and TES-26 antigens.

Varghese A, Raina OK, Chandra D, Mirdha BR, Kelawala NH, Solanki JB, Kumar N, Ravindran R, Arun A, Rialch A, Lalrinkima H, Kelawala RN, Samanta S.

Acta Parasitol. 2017 Dec 20;62(4):775-778. doi: 10.1515/ap-2017-0093.

PMID: 29035863 Similar articles Select item 2584380636.

Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes.

Janecek E, Wilk E, Schughart K, Geffers R, Strube C.

Int J Parasitol. 2015 Jun;45(7):495-503. doi: 10.1016/j.ijpara.2015.02.009. Epub 2015 Apr 3.

PMID: 25843806 Similar articles Select item 2880729137.

Toxocara canis: Analysis of the kinetics of antigen release and antibody production in an in vivo model for the detection of past or present infection.

Rodríguez-Caballero A, Martínez-Gordillo MN, Caballero-Salazar S, Rufino-González Y, Ponce-Macotela M.

Vet Parasitol. 2017 Aug 30;243:183-187. doi: 10.1016/j.vetpar.2017.06.027. Epub 2017 Jul 1.

PMID: 28807291 Similar articles Select item 2675189138.

Toxocara canis glycans influence antigen recognition by mouse IgG1 and IgM antibodies.

Długosz E, Wiśniewski M.

Acta Parasitol. 2016 Jan;61(1):191-4. doi: 10.1515/ap-2016-0026.

PMID: 26751891 Similar articles Select item 1278517439.

Human toxocariasis and ascariasis: concomitant parasitism in Srinagar, Kashmir, India.

Ahmad B, Bhatti G, Thokar MA, Malla N.

Indian J Pathol Microbiol. 2002 Jul;45(3):315-8.

PMID: 12785174 Similar articles Select item 2153798840.


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Toxocara canis larvae reinfecting BALB/c mice exhibit accelerated speed of migration to the host CNS.

Kolbeková P, Větvička D, Svoboda J, Skírnisson K, Leissová M, Syrůček M, Marečková H, Kolářová L.

Parasitol Res. 2011 Nov;109(5):1267-78. doi: 10.1007/s00436-011-2371-y. Epub 2011 May 3.

PMID: 21537988 Similar articles

Cross-reactivity of Toxocariasis with Crude Antigen of Toxascaris leonina Larvae by ELISA.

Jin Y, Shen C, Huh S, Choi MH, Hong ST.

J Korean Med Sci. 2015 May;30(5):549-51. doi: 10.3346/jkms.2015.30.5.549. Epub 2015 Apr 15.

PMID: 25931784 Free PMC Article Similar articles Select item 1291670442.

Diagnosis of parasitic zoonoses by immunoenzymatic assays--analysis of cross-reactivity among the excretory/secretory antigens of Fasciola hepatica, Toxocara canis, and Ascaris suum.

Romasanta A, Romero JL, Arias M, Sánchez-Andrade R, López C, Suárez JL, Díaz P, Díez-Baños P, Morrondo P, Paz-Silva A.

Immunol Invest. 2003 Aug;32(3):131-42.

PMID: 12916704 Similar articles Select item 2402557243.

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Biophysical analysis of astrocytes apoptosis triggered by larval E/S antigen from cerebral toxocarosis-causing pathogen Toxocara canis.

Hsiao WW, Liao HS, Lin HH, Lee YL, Fan CK, Liao CW, Lin PY, Hwu ET, Chang CS.

Anal Sci. 2013;29(9):885-92.

PMID: 24025572 Free Article Similar articles Select item 1021930444.

Detection of circulating antigens and antibodies in Toxocara canis infection among children in Chengdu, China.

Luo ZJ, Wang GX, Yang CI, Luo CH, Cheng SW, Liao L.

J Parasitol. 1999 Apr;85(2):252-6.

PMID: 10219304 Similar articles Select item 353285045.

Tissue localization of excretory-secretory antigens of larval Toxocara canis in acute and chronic murine toxocariasis.

Parsons JC, Bowman DD, Grieve RB.

Am J Trop Med Hyg. 1986 Sep;35(5):974-81.

PMID: 3532850 Similar articles Select item 2475490046.

Neurotoxocarosis: marked preference of Toxocara canis for the cerebrum and T. cati for the cerebellum in the paratenic model host mouse.

Janecek E, Beineke A, Schnieder T, Strube C.

Parasit Vectors. 2014 Apr 22;7:194. doi: 10.1186/1756-3305-7-194.

PMID: 24754900 Free PMC Article Similar articles Select item 1112734647.

Comparison of the sensitive screening kit with two ELISA sets for detection of anti-Toxocara antibodies.

Dubinsky P, Akao N, Reiterová K, Konáková G.

Southeast Asian J Trop Med Public Health. 2000 Jun;31(2):394-8.

PMID: 11127346 Similar articles Select item 1820182548.

Patent Toxocara canis infections in previously exposed and in helminth-free dogs after infection with low numbers of embryonated eggs.

Fahrion AS, Staebler S, Deplazes P.

Vet Parasitol. 2008 Mar 25;152(1-2):108-15. doi: 10.1016/j.vetpar.2007.11.022. Epub 2007 Dec 4.

PMID: 18201825 Similar articles Select item 2383263949.


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Toxocara spp. seroprevalence in sheep from southern Brazil.

Rassier GL, Borsuk S, Pappen F, Scaini CJ, Gallina T, Villela MM, da Rosa Farias NA, Benavides MV, Berne ME.

Parasitol Res. 2013 Sep;112(9):3181-6. doi: 10.1007/s00436-013-3499-8. Epub 2013 Jul 7.

PMID: 23832639 Similar articles Select item 1073157250.

Toxocara canis: genes expressed by the arrested infective larval stage of a parasitic nematode.

Maizels RM, Tetteh KK, Loukas A.

Int J Parasitol. 2000 Apr 10;30(4):495-508. Review.

PMID: 10731572 Similar articles Select item 2014929451.

Seroprevalence of Toxocara canis infection among children in Swaziland, southern Africa.

Liao CW, Sukati H, D'Lamini P, Chou CM, Liu YH, Huang YC, Chung MH, Mtsetfwa JS, Jonato J, Chiu WT, Chang PW, Du WY, Chan HC, Chu TB, Cheng HC, Su WW, Tu CC, Cheng CY, Fan CK.

Ann Trop Med Parasitol. 2010 Jan;104(1):73-80. doi: 10.1179/136485910X12607012373795.

PMID: 20149294 Similar articles Select item 1452157852.

Influence of maternal infection o­n offspring immune response in murine larval toxocariasis.

Reiterová K, Tomasovicová O, Dubinský P.

Parasite Immunol. 2003 Jul;25(7):361-8.

PMID: 14521578 Free Article Similar articles Select item 1470019653.

Population dynamics of Toxocara canis in pigs receiving a single or multiple infection.

Taira K, Saeed I, Lind P, Murrell KD, Kapel CM.

Parasitology. 2003 Dec;127(Pt 6):593-602.

PMID: 14700196 Similar articles Select item 1046956754.

A novel C-type lectin secreted by a tissue-dwelling parasitic nematode.

Loukas A, Mullin NP, Tetteh KK, Moens L, Maizels RM.

Curr Biol. 1999 Jul 29-Aug 12;9(15):825-8.

PMID: 10469567 Free Article Similar articles Select item 762918055.

An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins.

Gems D, Ferguson CJ, Robertson BD, Nieves R, Page AP, Blaxter ML, Maizels RM.

J Biol Chem. 1995 Aug 4;270(31):18517-22.

PMID: 7629180 Free Article Similar articles Select item 197853956.

Immunologic relevance of the cuticle and epicuticle of larval Dirofilaria immitis and Toxocara canis.

Grieve RB.

Acta Trop. 1990 Jul;47(5-6):399-402. Review.

PMID: 1978539 Similar articles Select item 2395443557.

The epidemiology and public health importance of toxocariasis: a zoonosis of global importance.

Macpherson CN.

Int J Parasitol. 2013 Nov;43(12-13):999-1008. doi: 10.1016/j.ijpara.2013.07.004. Epub 2013 Aug 14. Review.

PMID: 23954435Similar articles Select item 986980958.

Toxocara cati-induced ocular Toxocariasis.

Sakai R, Kawashima H, Shibui H, Kamata K, Kambara C, Matsuoka H.

Arch Ophthalmol. 1998 Dec;116(12):1686-7. No abstract available.

PMID: 9869809 Similar articles Select item 2604488359.

Toxocara canis mucins among other excretory-secretory antigens induce in vitro secretion of cytokines by mouse splenocytes.

Długosz E, Wasyl K, Klockiewicz M, Wiśniewski M.

Parasitol Res. 2015 Sep;114(9):3365-71. doi: 10.1007/s00436-015-4561-5. Epub 2015 Jun 6.

PMID: 26044883 Free PMC Article Similar articles Select item 319333460.

Pulmonary granuloma formation in murine toxocariasis: transfer of granulomatous hypersensitivity using bronchoalveolar lavage cells.

Kayes SG, Jones RE, Omholt PE.

J Parasitol. 1988 Dec;74(6):950-6.

PMID: 3193334 Similar articles

The infectivity and antigenicity of Toxocara canis eggs can be retained after long-term preservation.

Chung LY, Fang BH, Chang JH, Chye SM, Yen CM.

Ann Trop Med Parasitol. 2004 Apr;98(3):251-60.

PMID: 15119970 Similar articles Select item 1688640662.

[Investigations of the development of immunity in the course of experimental murine toxocariasis].

Wnukowska N, Dzbeńiski TH.

Wiad Parazytol. 2001;47(4):655-9. Polish.

PMID: 16886406 Similar articles Select item 1712555263.

Eosinophil cationic protein, specific IgE and IgG4 in human toxocariasis.

Magnaval JF, Faufingue JH, Morassin B, Fabre R.

J Helminthol. 2006 Dec;80(4):417-23.

PMID: 17125552 Similar articles Select item 129319564.

The use of 35S-labelled Toxocara canis to determine larval numbers in tissues.

Carter KC.

J Helminthol. 1992 Dec;66(4):279-87.

PMID: 1293195 Similar articles Select item 2591062365.

Field evaluation of a rapid diagnostic test to detect antibodies in human toxocariasis.

Lim PK, Yamasaki H, Mak JW, Wong SF, Chong CW, Yap IK, Ambu S, Kumarasamy V.

Acta Trop. 2015 Aug;148:32-7. doi: 10.1016/j.actatropica.2015.04.011. Epub 2015 Apr 22.

PMID: 25910623 Free Article Similar articles Select item 2551881866.

The hamster (Mesocricetus auratus) as an experimental model of toxocariasis: histopathological, immunohistochemical, and immunoelectron microscopic findings.

da Silva AM, Chieffi PP, da Silva WL, Kanashiro EH, Rubinsky-Elefant G, Cunha-Neto E, Mairena EC, De Brito T.

Parasitol Res. 2015 Mar;114(3):809-21. doi: 10.1007/s00436-014-4246-5. Epub 2014 Dec 19.

PMID: 25518818 Similar articles Select item 864368767.

An abundantly expressed mucin-like protein from Toxocara canis infective larvae: the precursor of the larval surface coat glycoproteins.

Gems D, Maizels RM.

Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1665-70.

PMID: 8643687 Free PMC Article Similar articles Select item 2578082368.

Epidemiology of human toxocariasis in Poland - A review of cases 1978-2009.

Borecka A, Kłapeć T.

Ann Agric Environ Med. 2015;22(1):28-31. doi: 10.5604/12321966.1141364. Review.

PMID: 25780823 Free Article Similar articles Select item 1996307569.

Parasite-specific antibody profile in the aqueous humor of rabbits with ocular toxocariasis.

Akiyama T, Ohta N.

Parasitol Int. 2010 Jun;59(2):112-20. doi: 10.1016/j.parint.2009.11.002. Epub 2009 Dec 4.

PMID: 19963075 Similar articles Select item 1572887570.

Prevalence of toxocariasis in northeastern Brazil based o­n serology using recombinant Toxocara canis antigen.

De Andrade Lima Coêlho R, De Carvalho LB Jr, Perez EP, Araki K, Takeuchi T, Ito A, Aoki T, Yamasaki H.

Am J Trop Med Hyg. 2005 Jan;72(1):103-7.

PMID: 15728875 Similar articles Select item 2322587071.


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The significance of cerebral toxocariasis: a model system for exploring the link between brain involvement, behaviour and the immune response.

Holland CV, Hamilton CM.

J Exp Biol. 2013 Jan 1;216(Pt 1):78-83. doi: 10.1242/jeb.074120.

PMID: 23225870 Free Article Similar articles Select item 2701594872.

Harnessing the Toxocara Genome to Underpin Toxocariasis Research and New Interventions.

Gasser RB, Korhonen PK, Zhu XQ, Young ND.

Adv Parasitol. 2016;91:87-110. doi: 10.1016/bs.apar.2015.12.001. Epub 2016 Feb 28. Review.

PMID: 27015948 Similar articles Select item 1596967673.

Persistent airway hyper-responsiveness and inflammation in Toxocara canis-infected BALB/c mice.

Pinelli E, Withagen C, Fonville M, Verlaan A, Dormans J, van Loveren H, Nicoll G, Maizels RM, van der Giessen J.

Clin Exp Allergy. 2005 Jun;35(6):826-32.

PMID: 15969676 Similar articles Select item 1211845674.

Sandwich ELISA detection of excretory-secretory antigens of Toxocara canis larvae using a specific monoclonal antibody.

Yokoi K, Kobayashi F, Sakai J, Usui M, Tsuji M.

Southeast Asian J Trop Med Public Health. 2002 Mar;33(1):33-7.

PMID: 12118456 Similar articles Select item 1112849375.


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Ocular larva migrans caused by Toxocara cati in Mongolian gerbils and a comparison of ophthalmologic findings with those produced by T. canis.

Akao N, Takayanagi TH, Suzuki R, Tsukidate S, Fujita K.

J Parasitol. 2000 Oct;86(5):1133-5.

PMID: 11128493 Similar articles Select item 1721701676.

Evaluation of crude and purified Toxocara canis antigens in serodiagnosis of human toxocariasis.

Abdel Aal TM, Youssef FG, el-Hady HM, Sabry NM, Habib KS, Saber JM.

J Egypt Public Health Assoc. 1996;71(3-4):321-41.

PMID: 17217016 Similar articles Select item 2022802977.

[Toxocara canis and bronchial asthma].

López Mde L, Bojanich MV, Jacobacci JM, Sercic C, Michelini A, Alonso JM.

Medicina (B Aires). 2010;70(1):75-8. Spanish.

PMID: 20228029 Similar articles Select item 1221911378.


Hình 9

Identification of toxocara canis antigens by Western blot in experimentally infected rabbits.

Morales OL, Lopez MC, Nicholls RS, Agudelo C.

Rev Inst Med Trop Sao Paulo. 2002 Jul-Aug;44(4):213-6.

PMID: 12219113 Free Article Similar articles Select item 670100379.

Characterization of surface and excretory-secretory antigens of Toxocara canis infective larvae.

Maizels RM, de Savigny D, Ogilvie BM.

Parasite Immunol. 1984 Jan;6(1):23-37.

PMID: 6701003 Similar articles Select item 2702755080.

Kinetics and avidity of anti-Toxocara antibodies (IgG) in rabbits experimentally infected with Toxocara canis.

Bin LL, Santarém VA, Laposy CB, Rubinsky-Elefant G, Roldán WH, Giuffrida R.

Rev Bras Parasitol Vet. 2016 Jan-Mar;25(1):99-104. doi: 10.1590/S1984-29612015067. Epub 2015 Nov 10.

PMID: 27027550 Free Article Similar articles

Cross-reactions with Ascaris suum antigens of sera from mice infected with A. suum, Toxocara canis, and Angiostrongylus cantonensis.

Fan CK, Su KE.

Parasitol Int. 2004 Sep;53(3):263-71.

PMID: 15468534 Similar articles Select item 2331287282.

Toxocara spp. infections in paratenic hosts.

Strube C, Heuer L, Janecek E.

Vet Parasitol. 2013 Apr 15;193(4):375-89. doi: 10.1016/j.vetpar.2012.12.033. Epub 2012 Dec 27. Review.

PMID: 23312872 Free Article Similar articles Select item 1831893783.


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rTES-30USM: cloning via assembly PCR, expression, and evaluation of usefulness in the detection of toxocariasis.

Norhaida A, Suharni M, Liza Sharmini AT, Tuda J, Rahmah N.

Ann Trop Med Parasitol. 2008 Mar;102(2):151-60. doi: 10.1179/136485908X252250.

PMID: 18318937 Similar articles Select item 2176753584.

Construction of a cDNA library from female adult of Toxocara canis, and analysis of EST and immune-related genes expressions.

Zhou R, Xia Q, Huang H, Lai M, Wang Z.

Exp Parasitol. 2011 Oct;129(2):120-6. doi: 10.1016/j.exppara.2011.07.005. Epub 2011 Jul 13.

PMID: 21767535 Similar articles Select item 1511507885.

Recombinant expression of Toxocara canis excretory-secretory antigen TES-120 in Escherichia coli.

Fong MY, Lau YL, Init I, Jamaiah I, Anuar AK, Rahmah N.

Southeast Asian J Trop Med Public Health. 2003 Dec;34(4):723-6.

PMID: 15115078 Similar articles Select item 1141238386.

Suppression of macrophage interleukin-12 and tumour necrosis factor-alpha production in mice infected with Toxocara canis.

Kuroda E, Yoshida Y, En Shan B, Yamashita U.

Parasite Immunol. 2001 Jun;23(6):305-11.

PMID: 11412383 Free Article Similar articles Select item 2519764587.


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Proteinases in excretory-secretory products of Toxocara canis second-stage larvae: zymography and modeling insights.

González-Páez GE, Alba-Hurtado F, García-Tovar CG, Argüello-García R.

Biomed Res Int. 2014;2014:418708. doi: 10.1155/2014/418708. Epub 2014 Aug 14.

PMID: 25197645 Free PMC Article Similar articles Select item 2153768188.

Identification of candidate antigens from adult stages of Toxocara canis for the serodiagnosis of human toxocariasis.

Peixoto PL, Nascimento E, Cançado GG, Miranda RR, Rocha RL, Araújo RN, Fujiwara RT.

Mem Inst Oswaldo Cruz. 2011 Mar;106(2):200-6.

PMID: 21537681 Free Article Similar articles Select item 1857589089.

Development of a highly sensitive IgG-ELISA based o­n recombinant arginine kinase of Toxocara canis for serodiagnosis of visceral larva migrans in the murine model.

Wickramasinghe S, Yatawara L, Nagataki M, Takamoto M, Watanabe Y, Rajapakse RP, Uda K, Suzuki T, Agatsuma T.

Parasitol Res. 2008 Sep;103(4):853-8. doi: 10.1007/s00436-008-1067-4. Epub 2008 Jun 25.

PMID: 18575890 Similar articles Select item 1976922990.

Hình 12

Method for detecting circulating Toxocara canis antigen and its application in human serum samples.

Ishiyamna S, o­no K, Rai SK, Uga S.

Nepal Med Coll J. 2009 Mar;11(1):9-13.

PMID: 19769229 Similar articles Select item 178018291.

Comparison of isolates and species of Toxocara and Toxascaris by biosynthetic labelling of somatic and ES proteins from infective larvae.

Page AP, Richards DT, Lewis JW, Omar HM, Maizels RM.

Parasitology. 1991 Dec;103 Pt 3:451-64.

PMID: 1780182 Similar articles Select item 2854310192.

Immunoglobulin M antibodies are not specific for serodiagnosis of human toxocariasis.

Roldán WH, Elefant GR, Ferreira AW.

Parasite Immunol. 2017 Aug;39(8). doi: 10.1111/pim.12447. Epub 2017 Jun 22.

PMID: 28543101 Similar articles Select item 2613539793.

New insights into the immunopathology of early Toxocara canis infection in mice.

Resende NM, Gazzinelli-Guimarães PH, Barbosa FS, Oliveira LM, Nogueira DS, Gazzinelli-Guimarães AC, Gonçalves MT, Amorim CC, Oliveira FM, Caliari MV, Rachid MA, Volpato GT, Bueno LL, Geiger SM, Fujiwara RT.

Parasit Vectors. 2015 Jul 2;8:354. doi: 10.1186/s13071-015-0962-7.

PMID: 26135397 Free PMC Article Similar articles Select item 2356975094.

A case report of ocular toxocariasis.

Azira NM, Zeehaida M.

Asian Pac J Trop Biomed. 2011 Apr;1(2):164-5. doi: 10.1016/S2221-1691(11)60018-X.

PMID: 23569750 Free PMC Article Similar articles Select item 1816712395.

Infection with the roundworm Toxocara canis leads to exacerbation of experimental allergic airway inflammation.

Pinelli E, Brandes S, Dormans J, Gremmer E, van Loveren H.

Clin Exp Allergy. 2008 Apr;38(4):649-58. doi: 10.1111/j.1365-2222.2007.02908.x. Epub 2007 Dec 20.

PMID: 18167123 Similar articles Select item 1059992996.

Hình 13

Immunomodulative effect of muramyldipeptide in mice with larval toxocarosis.

Dvoroznáková E, Borosková Z, Dubinský P, Tomasovicová O, Hríbalová V, Machnicka B.

Parasitol Res. 1999 Dec;85(12):1034-40.

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Larval toxocarosis in sheep: the immunohistochemical characterization of lesions in some affected organs.

Aldawek AM, Levkut M, Revajová V, Kolodzieyski L, Seveiková Z, Dubinský P.

Vet Parasitol. 2002 May 2;105(3):207-14.

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Genetic blueprint of the zoonotic pathogen Toxocara canis.

Zhu XQ, Korhonen PK, Cai H, Young ND, Nejsum P, von Samson-Himmelstjerna G, Boag PR, Tan P, Li Q, Min J, Yang Y, Wang X, Fang X, Hall RS, Hofmann A, Sternberg PW, Jex AR, Gasser RB.

Nat Commun. 2015 Feb 4;6:6145. doi: 10.1038/ncomms7145.

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Inhibition of interleukin 5 production with no influence o­n interleukin 4 production by an anti-allergic drug, tranilast, in Toxocara canis-infected mice.

Hiratochi M, Takamoto M, Tatemichi S, Sugane K.

Int J Immunopharmacol. 2000 Jun;22(6):463-71.

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Prevalence of Toxocara antibodies among patients clinically suspected to have ocular toxocariasis: A retrospective descriptive study in Sri Lanka.

Iddawela D, Ehambaram K, Bandara P.

BMC Ophthalmol. 2017 Apr 24;17(1):50. doi: 10.1186/s12886-017-0444-0.

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The in vitro effect of prolactin o­n the growth, motility and expression of prolactin receptors in larvae of Toxocara canis.

Chávez-Güitrón LE, Morales-Montor J, Muñoz-Guzmán MA, Nava-Castro KE, Ramírez-Álvarez H, Moreno-Méndoza NA, Hernández-Cervantes R, Alba-Hurtado F.

Vet Parasitol. 2016 Jul 15;224:33-38. doi: 10.1016/j.vetpar.2016.05.004. Epub 2016 May 3.

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Persistence of specific antibody response in different experimental infections of mice with Toxocara canis larvae.

Chieffi PP, Peres BA, de Mello EO, Kanamura H, Brandão MM.

Rev Inst Med Trop Sao Paulo. 1995 May-Jun;37(3):187-90.

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Lactobacillus rhamnosus reduces parasite load o­n Toxocara canis experimental infection in mice, but has no effect o­n the parasite in vitro.

Walcher DL, Cruz LAX, de Lima Telmo P, Martins LHR, da Costa de Avila LF, Berne MEA, Scaini CJ.

Parasitol Res. 2018 Feb;117(2):597-602. doi: 10.1007/s00436-017-5712-7. Epub 2017 Dec 14.

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Prolactin as immune cell regulator in Toxocara canis somatic larvae chronic infection.

Del Rio-Araiza VH, Nava-Castro KE, Alba-Hurtado F, Quintanar-Stephano A, Aguilar-Díaz H, Muñoz-Guzmán MA, Ostoa-Saloma P, Ponce-Regalado MD, Morales-Montor J.

Biosci Rep. 2018 Jun 19. pii: BSR20180305. doi: 10.1042/BSR20180305. [Epub ahead of print]

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Variations in innate resistance to experimental Toxocara canis infection in two strains of mice.

Abo-Shehada MN, Herbert IV.

Vet Parasitol. 1989 Oct;33(3-4):297-307.

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Modulation of the host's immune response by schistosome larvae.

Jenkins SJ, Hewitson JP, Jenkins GR, Mountford AP.

Parasite Immunol. 2005 Oct-Nov;27(10-11):385-93. Review.

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Evaluation of the transcription of interleukin-12 in the intestinal mucosa of mice subjected to experimental toxocariasis and supplemented with Saccharomyces boulardii.

de Moura MQ, da Silva Terto WD, Jeske ST, de Castro LM, Pinto NB, da Costa Avila LF, Leite FPL, Berne MEA.

Vet Parasitol. 2017 Aug 15;242:59-62. doi: 10.1016/j.vetpar.2017.05.012. Epub 2017 May 30. No abstract available.

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Glycoimmunology: ignore at your peril!

Baum LG, Crocker PR.

Immunol Rev. 2009 Jul;230(1):5-8. doi: 10.1111/j.1600-065X.2009.00800.x. No abstract available.

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Ngày 06/07/2018
TS.BS. Huỳnh Hồng Quang  

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