Update on malaria research publications in May 2016
1. A Novel Route to Malaria Treatments: Semisynthetic Artemisinin This infographic illustrates the key achievements of the project to establish and validate a manufacturing process to produce semisynthetic artemisinin (ssART) at industrial scale and commercialize ssART. Production of ssART aims to supplement a historically volatile botanical supply chain, strengthening the artemisinin market and ensuring that the global need for artemisinin-based combination therapies can be met, thus supporting current worldwide malaria control measures and strategies for malaria elimination. Publication date: April 2016; Region: Global; 2. PATH Center for Malaria Control and Elimination PATH?s Center for Malaria Control and Elimination is building on our unparalleled portfolio of malaria tools and projects, encompassing a broad collection of competencies and expertise, to advance efforts toward elimination, and ultimately eradication, of both P. falciparum and P. vivax malaria. Publication date: April 2016; Region: Global; 3. Saving Lives in Kenya: Advocating for a Better Future for Women, Newborns, and Children PATH is working with the government of Kenya to advance evidence-based policy solutions at the national level and in select counties to save lives and improve health in local communities. Publication date: April 2016; Region: Africa; 4. PATH in Ethiopia This four-page brochure highlights how PATH accelerates data-driven innovation to improve health and save lives in Ethiopia. Key focus areas include malaria, tuberculosis, immunization, and newborn and child health. Publication date: January 2016; Region: Africa, Part of series: 5. Country brochures PATH in Tanzania This four-page brochure highlights how PATH uses innovation, integration of services, and better data systems to improve health and save lives in Tanzania. Key focus areas include malaria, tuberculosis, immunization, disease surveillance, and child health. Publication date: January 2016; Region: Africa; Part of series: 6. Country brochures PATH in the Democratic Republic of the Congo This brochure provides an overview of PATH?s work in the Democratic Republic of the Congo. It describes our key strategies to combat HIV/AIDS, tuberculosis, malaria, and neglected tropical diseases and improve reproductive, maternal, and child health. Publication date: January 2016; Region: Africa; Part of series: 7. Country brochures; Drug Development Global Program Website This website about PATH?s drug development program provides an overview of the program and its featured projects. See other PATH program websites. Publication date: 2016; Region: Global; Part of series: Program websites; 8. Ethiopia Country Program Website This website about PATH?s Ethiopia country program provides an overview of the program and its featured projects. See other PATH program websites. Publication date: 2016; Region: Africa; Part of series: Program websites, 9. Making Malaria History Website This website features updates on the latest malaria research and news, resources for advocates and technical partners, evidence and progress from the global malaria community, and field tools currently being used by countries at the forefront of the fight against the disease. Publication date: 2016; Region: Africa; Part of series: Websites, 10. Malaria Control and Evaluation Partnership in Africa Global Program Website This website about PATH?s Malaria Control and Evaluation Partnership in Africa (MACEPA) global program provides an overview of the program and its featured projects. See other PATH program websites. Publication date: 2016; Region: Global; Part of series: Program websites 11. Malaria Vaccine Initiative Global Program Website This website about PATH?s Malaria Vaccine Initiative (MVI) global program provides an overview of the program and its featured projects. See other PATH program websites. Publication date: 2016, Region: Global, Part of series: Program websites, 12. Malaria Vaccine Initiative Website Launched in 2002, this website provides information on the Malaria Vaccine Initiative at PATH. Publication date: 2016, Region: Global, Part of series: Websites, 13. Tanzania Country Program Website This website about PATH?s Tanzania country program provides an overview of the program and its featured projects. See other PATH program websites. Publication date: 2016; Region: Africa; Part of series: Program websites 14. Zambia Country Program Website This website about PATH?s Zambia country program provides an overview of the program and its featured projects. See other PATH program websites. Publication date: 2016; Region: Africa; Part of series: Program websites, 15. Fighting Malaria Today and Tomorrow: PATH Works With Partners and Countries to Achieve a Malaria-Free World This fact sheet describes PATH's work to eliminate malaria, including expanding the use of lifesaving tools, identifying and developing better diagnostics and drugs, devising new strategies for malaria control, and accelerating the development of malaria vaccines. Publication date: April 2015; Region: Global; Part of series: Areas of focus fact sheets 16. Driving Development and Adoption of Malaria Diagnostic Tools PATH is a leader in the innovation, promotion, and adoption of diagnostic technologies to support malaria elimination and ultimately eradication. As a whole, malaria-related projects and programs at PATH form a core of organizational expertise and strong infrastructure to accelerate the development and adoption of new and improved malaria diagnostics. Publication date: March 2015; Region: Global, 17. Policies and Actions for Improved Malaria in Pregnancy Efforts in Communities Emerging evidence in Kenya and other sub-Saharan African countries reveals the importance of using community-based approaches to ensure that all pregnant women have access to preventive malaria care. In Nairobi, Kenya, PATH convened government officials, leading experts, and civil society representatives to share research and discuss recommendations for policy change. Publication date: March 2015; Region: Africa; 18. USAID and PATH: Working Together to Improve Global Health PATH and the US Agency for International Development (USAID) work together to promote and improve health in developing countries. This fact sheet provides examples of successes that PATH, USAID, and our private partners have had in advancing technologies, strengthening health systems, and encouraging healthy behaviors to improve health and allow communities around the world to prosper. Publication date: January 2015; Region: North America and Europe, 19. GlobalA Healthy Dose A Healthy Dose from PATH?s Drug Development program gives advocates, policymakers, government and agency leaders, and anyone interested in global health a quarterly update on our work. Each issue features reports from the field, news on the latest clinical trial milestones, and resources in nonprofit drug development. Publication date: 2015; Region: Global; Part of series: E-newsletters 20. Making Malaria History Newsletter The Making Malaria History newsletter is a periodic update on activities of the Malaria Control and Evaluation Partnership in Africa, which works to rapidly scale up proven malaria control interventions to achieve impact on health and economic indicators. Distributed three times per year, the newsletter includes updates on emerging malaria control insights, as well as perspectives from Zambia and our regional and global partners. Publication date: 2015; 21. Policies and Actions for More Effective Malaria in Pregnancy Efforts: Maternal and Newborn Health in Kenya In Kenya, malaria in pregnancy continues to contribute to high maternal and newborn morbidity and mortality. By translating emerging evidence on community-based distribution of antimalarial medicine into policy action, policymakers in Kenya have the opportunity to significantly decrease malaria-related mortality and morbidity during pregnancy, safeguarding the health and lives of countless women and newborns. This brief describes recommendations and policies at the global level and in Kenya and identifies ways in which to expand access to preventive treatment for mothers. Publication date: October 2014; Region: Africa; 22. Community-Based Approach to Intermittent Preventive Treatment for Malaria in Pregnancy in Kisumu, Kenya: Exploring the Value of Utilizing Community Health Workers in Malaria in Pregnancy Prevention In sub-Saharan Africa, malaria in pregnancy continues to contribute to high maternal and newborn morbidity and mortality. In Kisumu, Kenya, PATH developed a two-phased approach to increase coverage of malaria in pregnancy prevention activities and strengthen antenatal care. This report details the activities and outcomes of the pilot project and offers recommendations for next steps. See also Community-Based Approaches to Intermittent Preventive Treatment of Malaria in Pregnancy: A Review of Recent Studies. Publication date: September 2014; Region: Africa; 23. Community-Based Approaches to Intermittent Preventive Treatment of Malaria in Pregnancy: A Review of Recent Studies In sub-Saharan Africa, malaria in pregnancy continues to contribute to high maternal and newborn morbidity and mortality. one approach to the problem is intermittent preventive treatment of malaria in pregnancy with sulfadoxine pyrimethamine, an antimalarial safe for use in pregnancy. This report reviews recent studies and articles documenting implementation of community-based approaches that increase uptake of this therapy. See also Community-Based Approach to Intermittent Treatment for Malaria in Pregnancy in Kisumu, Kenya: Exploring the Value of Utilizing Community Health Workers in Malaria in Pregnancy Prevention. Publication date: September 2014; Region: Africa; 24. Stabilizing the Antimalarial Drug Supply: Semisynthetic Artemisinin Could Meet up to one-Third of Global Need Artemisinin-based combination therapy is considered the gold standard treatment for malaria, but global demand has often outpaced production, and pricing has been volatile. This fact sheet describes the cross-sector partnership PATH formed to develop a new way to produce high-quality, nonseasonal, and affordable artemisinin to supplement the plant-based supply. Publication date: July 2014; Region: Global; 25. Accelerating Malaria Elimination in Africa: PATH Partners With Malaria-Endemic Countries, the Private Sector, and the Global Community in the Quest for a Malaria-Free World This fact sheet provides an overview of the work of PATH's Malaria Control and Elimination Partnership in Africa (MACEPA) to develop and document approaches for reducing malaria illnesses and deaths, with the long-term goal of malaria elimination. Publication date: April 2014; Region: Africa; 26. Rapid, Point-of-Care Test for Glucose-6 Phosphate Dehydrogenase Deficiency Part of the Technology Updates series, this fact sheet describes PATH?s work with diagnostic developers and stakeholders from around the world to develop a rapid, point-of-care diagnostic test for glucose-6 phosphate dehydrogenase (G6PD) deficiency. A reliable test for G6PD at the point of care is essential to malaria elimination strategies. Publication date: April 2014; Region: Global; Part of series: Technology Updates 27. Semisynthetic Artemisinin: Cross-Sector Partnership to Stabilize the Antimalarial Drug Supply Artemisinin-based combination therapy is considered the gold standard treatment for malaria, but global demand has often outpaced production, and pricing has been volatile. With funding from the Bill & Melinda Gates Foundation, PATH and our partners set out to develop a new pharmaceutical manufacturing process to produce commercial volumes of high-quality, nonseasonal, and affordable artemisinin to supplement the plant-based supply. This poster, presented at the Bay Area World Malaria Day Symposium on April 25, 2014, presents key facts on malaria, the market for artemisinin, partner roles, and commercial production. Publication date: April 2014; Region: Global; 28. MalariaCare - Universal Diagnosis and Treatment to Improve Maternal and Child Health This fact sheet describes the MalariaCare partnership, a five-year effort led by PATH and funded by the US Agency for International Development and the President's Malaria Initiative. The project aims to scale up high-quality diagnosis and treatment services for malaria and other life-threatening illnesses. Publication date: January 2014; Region: Global; 29. From Pipeline to Product: Malaria R&D Funding Needs Into the Next Decade This report, a follow-on to the 2011 report Staying the Course? Malaria Research and Development in a Time of Economic Uncertainty, tracks malaria research and development funding from 2007 to 2011 and provides estimates on funding needs through 2022. Publication date: December 2013; Region: Global; 30. Improving Women's and Children's Health in Senegal This fact sheet provides an overview of PATH's work in Senegal. Since 2001, PATH has worked side by side with government and community partners in Senegal to reduce the burden of infectious disease, improve family planning and reproductive health, and strengthen health systems to save lives. Publication date: December 2013; Region: Africa, 31. Overview of Nucleic Acid?Based Diagnostic Techniques To support a World Health Organization (WHO) Evidence Review Group on Malaria Diagnostics in Low-Transmission Settings in December 2013, PATH was invited to provide an overview of polymerase chain reaction and isothermal molecular methods for malaria infection detection. The PowerPoint is provided here and the WHO policy recommendations from the evidence review can be found here. Author: LaBarre P, Tietje K; Publication date: December 2013; Region: Global; 32. Maximizing the Impact of Our Work: PATH's Impact Initiatives Drive Innovation and Improve Health Outcomes Through Targeted Investments This fact sheet highlights PATH's Impact Initiatives. Through these initiatives, cross-program teams identify high-priority health areas for improvement, set institutional goals, and then mobilize resources to achieve them. Each initiative focuses on carefully selected countries and innovations. Publication date: September 2013; Region: Global; Part of series: Areas of focus fact sheets 33. 2012 Annual Report: Innovation in Motion PATH?s health solutions touched the lives of more than 118 million people around the world in 2012. Our 2012 annual report highlights our milestones in three focus areas: diarrheal disease and pneumonia; family health; and malaria. It also features innovations in technology development and country-based health programs, a financial summary, and information about our donors, leadership, and global presence. Publication date: May 2013; Region: Global; Part of series: Annual reports; 34. Directions in Global Health (Volume 10, Issue 1) This issue of Directions in Global Health features work by oneWorld Health, PATH?s drug development program, to lead development of innovative methods to enhance the supply of artemisinin, a key ingredient in malaria treatments. It includes a commentary by Dr. Ponni Subbiah, who directs PATH?s drug development efforts. Other articles cover work to improve cervical cancer screening, protect infants from respiratory syncytial virus, increase access to family planning, and strengthen and expand use of human milk banking. Publication date: May 2013; Region: Global; Part of series: 35. Directions in Global Health PATH Today (Spring 2013) This issue of PATH Today describes PATH's multipronged approach to eliminating malaria in Africa and the development of semisynthetic artemisinin, a key ingredient in malaria treatment. It includes updates on PATH's work to prevent diarrhea in Cambodia and to diagnose cervical cancer. It also contains a profile of Dean Allen, CEO of McKinstry and PATH's board treasurer. Publication date: May 2013; Region: Global; Part of series: PATH Today; 36. Investing in Malaria Pays Off This infographic gives a visual representation of the cost-effectiveness of malaria interventions in Africa, showing that the malaria map is shrinking and that investing in malaria pays off. Publication date: 2013; Region: Africa; 37. Malaria Test for Life This infographic gives a visual representation of PATH's three-step approach to test and treat malaria infections: rapid reporting, mass test and treat, and active surveillance. Publication date: 2013; Region: Africa; 38. A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants This article, published in the New England Journal of Medicine (NEJM), reports results from a pivotal, large-scale Phase 3 trial of RTS,S/AS01 malaria vaccine. When compared to immunization with a control vaccine, infants (aged 6 to 12 weeks at first vaccination) vaccinated with RTS,S had one-third fewer episodes of both clinical and severe malaria and had similar reactions to the injection. In this trial, RTS,S demonstrated an acceptable safety and tolerability profile. The abstract of this article is available through the NEJM by clicking on "Visit web page" below, or for free access to the full lenth article please visit malariavaccine.org and click on "Read the NEJM article." Publication date: December 2012; Region: Africa; 39. The PATH Malaria Vaccine Initiative The PATH Malaria Vaccine Initiative (MVI) is a vaccine development program of PATH. This fact sheet provides an overview of MVI's history, mission, vision, and work. Publication date: November 2012; Region: Global ; 40. PATH Today (Winter 2012) This issue of PATH Today leads with the Mama SASHA project, which is improving nutrition, agriculture, and prenatal health care in Kenya. PATH's work to increase access to breast cancer screening in rural Peru is also featured, and donors Bryan and Martha Kim share why contributing to PATH is a smart investment. News briefs include an update about family planning and new work in Myanmar. Publication date: November 2012; Region: Global; Part of series: PATH Today
|